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Activity of nimesulide on constitutive and inducible cyclooxygenases.
Tavares IA, Bishai PM, Bennett A. Tavares IA, et al. Among authors: bennett a. Arzneimittelforschung. 1995 Oct;45(10):1093-5. Arzneimittelforschung. 1995. PMID: 8595066
With the in vitro assay, nimesulide (0.01 to 100 mumol/l) did not inhibit PGE formation by COX-1 but caused a concentration-related inhibition of PGE formation by COX-2 (4-60%). ...
With the in vitro assay, nimesulide (0.01 to 100 mumol/l) did not inhibit PGE formation by COX-1 but caused a concentration-related i …
Non-steroidal anti-inflammatory drugs that cause relatively little gastric damage.
Tavares IA, Bennett A. Tavares IA, et al. Among authors: bennett a. J Gastroenterol Hepatol. 1998 Nov;13(S3):S190-S192. doi: 10.1111/j.1440-1746.1998.tb01875.x. J Gastroenterol Hepatol. 1998. PMID: 28976651
All results with nimesulide are consistent with a preferential block of COX-2 that contributes to relatively little gastric damage in patients. ...
All results with nimesulide are consistent with a preferential block of COX-2 that contributes to relatively little gastric damage in …
High molecular weight phospholipase A2 and fatty acids in human colon tumours and associated normal tissue.
Soydan AS, Tavares IA, Weech PK, Temblay NM, Bennett A. Soydan AS, et al. Among authors: bennett a. Eur J Cancer. 1996 Sep;32A(10):1781-7. doi: 10.1016/0959-8049(96)00166-9. Eur J Cancer. 1996. PMID: 8983290
Total lipids extracted from homogenised surgical specimens were transesterified and fatty acids were analysed by gas chromatography. cPLA2 was separated by SDS-PAGE, Western-blotted, immunoblotted using a specific antibody to cPLA2 and semiquantified following enhanced che …
Total lipids extracted from homogenised surgical specimens were transesterified and fatty acids were analysed by gas chromatography. cPLA2 w …
Effect of pirazolac on prostanoid synthesis by human gastric mucosa in vitro.
Tavares IA, Bennett A. Tavares IA, et al. Among authors: bennett a. Drugs Exp Clin Res. 1990;16(1):1-6. Drugs Exp Clin Res. 1990. PMID: 2115830
The effect of folate on the methotrexate/indomethacin interaction in a murine cancer cell line.
Hollingsworth SJ, Anderson EM, Bennett A. Hollingsworth SJ, et al. Among authors: bennett a. Br J Pharmacol. 1995 Sep;116(2):1809-14. doi: 10.1111/j.1476-5381.1995.tb16667.x. Br J Pharmacol. 1995. PMID: 8528564 Free PMC article.
The effect of folate on the interaction between methotrexate (a folate analogue) and indomethacin has been examined in murine NC carcinoma cells. 2. Conditioning of NC cells to a physiological (20 nM) folate concentration after culture in a high folate concen …
The effect of folate on the interaction between methotrexate (a folate analogue) and indomethacin has been examined in murine NC carc …
Interaction between methotrexate and indomethacin on a human normal haemopoietic cell line.
Hollingsworth SJ, Shankley NP, Anderson EM, Bennett A. Hollingsworth SJ, et al. Among authors: bennett a. Br J Pharmacol. 1995 Feb;114(3):715-9. doi: 10.1111/j.1476-5381.1995.tb17197.x. Br J Pharmacol. 1995. PMID: 7735697 Free PMC article.
The interaction between methotrexate and indomethacin has been examined, at a physiological folate concentration (20 nM), on a human normal lymphoblast-like cell line (RPMI 1788) in vitro. 2. ...If indomethacin increases the killing of human cancer cells by methotre …
The interaction between methotrexate and indomethacin has been examined, at a physiological folate concentration (20 nM), on a
Effect of lignocaine on eicosanoid synthesis by pieces of human gastric mucosa.
Goel RK, Tavares IA, Nellgard P, Jonsson A, Cassuto J, Bennett A. Goel RK, et al. Among authors: bennett a. J Pharm Pharmacol. 1994 Apr;46(4):319-20. doi: 10.1111/j.2042-7158.1994.tb03803.x. J Pharm Pharmacol. 1994. PMID: 8051618
Acemetacin and indomethacin: differential inhibition of constitutive and inducible cyclo-oxygenases in human gastric mucosa and leucocytes.
Tavares IA, Bennett A. Tavares IA, et al. Among authors: bennett a. Int J Tissue React. 1993;15(2):49-53. Int J Tissue React. 1993. PMID: 8144313
Cyclo-oxygenase, a key enzyme in prostaglandin production, is mainly in the constitutive form (COX-1) in gastric mucosa, whereas leucocytes have an inducible enzyme (COX-2). ...In gastric mucosal incubates, acemetacin was less potent than indomethacin in causing a c …
Cyclo-oxygenase, a key enzyme in prostaglandin production, is mainly in the constitutive form (COX-1) in gastric mucosa, whereas leuc …
The production of prostanoids in human cancers, and their implications for tumor progression.
Bennett A. Bennett A. Prog Lipid Res. 1986;25(1-4):539-42. doi: 10.1016/0163-7827(86)90109-8. Prog Lipid Res. 1986. PMID: 3321094 Review. No abstract available.
Inhibition of prostanoid synthesis by human gastric mucosa.
Tavares IA, Collins PO, Bennett A. Tavares IA, et al. Among authors: bennett a. Aliment Pharmacol Ther. 1987 Dec;1(6):617-25. doi: 10.1111/j.1365-2036.1987.tb00647.x. Aliment Pharmacol Ther. 1987. PMID: 2979689
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