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180 results
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Structural insight into potent broad-spectrum inhibition with reversible recyclization mechanism: avibactam in complex with CTX-M-15 and Pseudomonas aeruginosa AmpC β-lactamases.
Lahiri SD, Mangani S, Durand-Reville T, Benvenuti M, De Luca F, Sanyal G, Docquier JD. Lahiri SD, et al. Among authors: benvenuti m. Antimicrob Agents Chemother. 2013 Jun;57(6):2496-505. doi: 10.1128/AAC.02247-12. Epub 2013 Feb 25. Antimicrob Agents Chemother. 2013. PMID: 23439634 Free PMC article.
Crystal structure of the narrow-spectrum OXA-46 class D beta-lactamase: relationship between active-site lysine carbamylation and inhibition by polycarboxylates.
Docquier JD, Benvenuti M, Calderone V, Giuliani F, Kapetis D, De Luca F, Rossolini GM, Mangani S. Docquier JD, et al. Among authors: benvenuti m. Antimicrob Agents Chemother. 2010 May;54(5):2167-74. doi: 10.1128/AAC.01517-09. Epub 2010 Feb 9. Antimicrob Agents Chemother. 2010. PMID: 20145076 Free PMC article.
High-resolution crystal structure of the subclass B3 metallo-beta-lactamase BJP-1: rational basis for substrate specificity and interaction with sulfonamides.
Docquier JD, Benvenuti M, Calderone V, Stoczko M, Menciassi N, Rossolini GM, Mangani S. Docquier JD, et al. Among authors: benvenuti m. Antimicrob Agents Chemother. 2010 Oct;54(10):4343-51. doi: 10.1128/AAC.00409-10. Epub 2010 Aug 9. Antimicrob Agents Chemother. 2010. PMID: 20696874 Free PMC article.
Structure of the extended-spectrum β-lactamase TEM-72 inhibited by citrate.
Docquier JD, Benvenuti M, Calderone V, Rossolini GM, Mangani S. Docquier JD, et al. Among authors: benvenuti m. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Mar 1;67(Pt 3):303-6. doi: 10.1107/S1744309110054680. Epub 2011 Feb 18. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011. PMID: 21393831 Free PMC article.
4-Amino-1,2,4-triazole-3-thione-derived Schiff bases as metallo-β-lactamase inhibitors.
Gavara L, Sevaille L, De Luca F, Mercuri P, Bebrone C, Feller G, Legru A, Cerboni G, Tanfoni S, Baud D, Cutolo G, Bestgen B, Chelini G, Verdirosa F, Sannio F, Pozzi C, Benvenuti M, Kwapien K, Fischer M, Becker K, Frère JM, Mangani S, Gresh N, Berthomieu D, Galleni M, Docquier JD, Hernandez JF. Gavara L, et al. Among authors: benvenuti m. Eur J Med Chem. 2020 Dec 15;208:112720. doi: 10.1016/j.ejmech.2020.112720. Epub 2020 Aug 20. Eur J Med Chem. 2020. PMID: 32937203
Discovery of ANT3310, a Novel Broad-Spectrum Serine β-Lactamase Inhibitor of the Diazabicyclooctane Class, Which Strongly Potentiates Meropenem Activity against Carbapenem-Resistant Enterobacterales and Acinetobacter baumannii.
Davies DT, Leiris S, Zalacain M, Sprynski N, Castandet J, Bousquet J, Lozano C, Llanos A, Alibaud L, Vasa S, Pattipati R, Valige R, Kummari B, Pothukanuri S, De Piano C, Morrissey I, Holden K, Warn P, Marcoccia F, Benvenuti M, Pozzi C, Tassone G, Mangani S, Docquier JD, Pallin D, Elliot R, Lemonnier M, Everett M. Davies DT, et al. Among authors: benvenuti m. J Med Chem. 2020 Dec 24;63(24):15802-15820. doi: 10.1021/acs.jmedchem.0c01535. Epub 2020 Dec 11. J Med Chem. 2020. PMID: 33306385
180 results