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ADME/PK as part of a rational approach to drug discovery.
Eddershaw PJ, Beresford AP, Bayliss MK. Eddershaw PJ, et al. Among authors: beresford ap. Drug Discov Today. 2000 Sep;5(9):409-414. doi: 10.1016/s1359-6446(00)01540-3. Drug Discov Today. 2000. PMID: 10931658
CYP1A1: friend or foe?
Beresford AP. Beresford AP. Drug Metab Rev. 1993;25(4):503-17. doi: 10.3109/03602539308993984. Drug Metab Rev. 1993. PMID: 8313840 Review. No abstract available.
Development of a series of aryl pyrimidine kynurenine monooxygenase inhibitors as potential therapeutic agents for the treatment of Huntington's disease.
Toledo-Sherman LM, Prime ME, Mrzljak L, Beconi MG, Beresford A, Brookfield FA, Brown CJ, Cardaun I, Courtney SM, Dijkman U, Hamelin-Flegg E, Johnson PD, Kempf V, Lyons K, Matthews K, Mitchell WL, O'Connell C, Pena P, Powell K, Rassoulpour A, Reed L, Reindl W, Selvaratnam S, Friley WW, Weddell DA, Went NE, Wheelan P, Winkler C, Winkler D, Wityak J, Yarnold CJ, Yates D, Munoz-Sanjuan I, Dominguez C. Toledo-Sherman LM, et al. J Med Chem. 2015 Feb 12;58(3):1159-83. doi: 10.1021/jm501350y. Epub 2015 Jan 23. J Med Chem. 2015. PMID: 25590515
Metabolism and kinetics of amlodipine in man.
Beresford AP, McGibney D, Humphrey MJ, Macrae PV, Stopher DA. Beresford AP, et al. Xenobiotica. 1988 Feb;18(2):245-54. doi: 10.3109/00498258809041660. Xenobiotica. 1988. PMID: 2967593
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