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On the maintenance of hepatocyte intracellular pH 7.0 in the in-vitro metabolic stability assay.
Berezhkovskiy LM, Wong S, Halladay JS. Berezhkovskiy LM, et al. J Pharmacokinet Pharmacodyn. 2013 Dec;40(6):683-9. doi: 10.1007/s10928-013-9339-8. Epub 2013 Nov 1. J Pharmacokinet Pharmacodyn. 2013. PMID: 24178037
On the accuracy of a one-compartment approach for determination of drug terminal half-life.
Berezhkovskiy LM. Berezhkovskiy LM. J Pharm Sci. 2013 Jul;102(7):2082-4. doi: 10.1002/jps.23565. Epub 2013 Apr 25. J Pharm Sci. 2013. PMID: 23620272
Prediction of drug terminal half-life and terminal volume of distribution after intravenous dosing based on drug clearance, steady-state volume of distribution, and physiological parameters of the body.
Berezhkovskiy LM. Berezhkovskiy LM. J Pharm Sci. 2013 Feb;102(2):761-71. doi: 10.1002/jps.23396. Epub 2012 Dec 11. J Pharm Sci. 2013. PMID: 23233148
Determination of hepatic clearance with the account of drug-protein binding kinetics.
Berezhkovskiy LM. Berezhkovskiy LM. J Pharm Sci. 2012 Oct;101(10):3936-45. doi: 10.1002/jps.23235. Epub 2012 Jul 5. J Pharm Sci. 2012. PMID: 22767378
On the accuracy of determination of unbound drug fraction in tissue using diluted tissue homogenate.
Berezhkovskiy LM. Berezhkovskiy LM. J Pharm Sci. 2012 May;101(5):1909-16. doi: 10.1002/jps.23073. Epub 2012 Feb 13. J Pharm Sci. 2012. PMID: 22331662
A convenient method to measure blood-plasma concentration ratio using routine plasma collection in in vivo pharmacokinetic studies.
Berezhkovskiy LM, Zhang X, Cheong J. Berezhkovskiy LM, et al. J Pharm Sci. 2011 Dec;100(12):5293-8. doi: 10.1002/jps.22709. Epub 2011 Jul 20. J Pharm Sci. 2011. PMID: 21780122
On the possibility of self-induction of drug protein binding.
Berezhkovskiy LM. Berezhkovskiy LM. J Pharm Sci. 2010 Oct;99(10):4400-5. doi: 10.1002/jps.22126. J Pharm Sci. 2010. PMID: 20737641
On the influence of protein binding on pharmacological activity of drugs.
Berezhkovskiy LM. Berezhkovskiy LM. J Pharm Sci. 2010 Apr;99(4):2153-65. doi: 10.1002/jps.21958. J Pharm Sci. 2010. PMID: 19827100
Prediction of the possibility of the secondary peaks of iv bolus drug plasma concentration time curve by the model that directly takes into account the transit time through the organ.
Berezhkovskiy LM. Berezhkovskiy LM. J Pharm Sci. 2009 Nov;98(11):4376-90. doi: 10.1002/jps.21715. J Pharm Sci. 2009. PMID: 19340884
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