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ROS-dependent phosphorylation of Bax by wortmannin sensitizes melanoma cells for TRAIL-induced apoptosis.
Quast SA, Berger A, Eberle J. Quast SA, et al. Cell Death Dis. 2013 Oct 10;4(10):e839. doi: 10.1038/cddis.2013.344. Cell Death Dis. 2013. PMID: 24113173 Free PMC article.
The data unraveled a mechanism by which NOX4-dependent ROS production controls apoptosis via Bax phosphorylation. The pathway may be considered for proapoptotic, anticancer strategies....
The data unraveled a mechanism by which NOX4-dependent ROS production controls apoptosis via Bax phosphorylation. The pathway may be …
Sensitization of melanoma cells for TRAIL-induced apoptosis by BMS-345541 correlates with altered phosphorylation and activation of Bax.
Berger A, Quast SA, Plötz M, Kammermeier A, Eberle J. Berger A, et al. Cell Death Dis. 2013 Jan 24;4(1):e477. doi: 10.1038/cddis.2012.198. Cell Death Dis. 2013. PMID: 23348591 Free PMC article.
Applying a melanoma model of TRAIL-sensitive and -resistant cell lines, efficient sensitization for TRAIL-induced apoptosis is demonstrated by the kinase inhibitor BMS-345541 (N-(1,8-dimethylimidazo(1,2-a)quinoxalin-4-yl)-1,2-ethanediamine hydrochloride), which targ …
Applying a melanoma model of TRAIL-sensitive and -resistant cell lines, efficient sensitization for TRAIL-induced apoptosis is demons …
PAK-dependent STAT5 serine phosphorylation is required for BCR-ABL-induced leukemogenesis.
Berger A, Hoelbl-Kovacic A, Bourgeais J, Hoefling L, Warsch W, Grundschober E, Uras IZ, Menzl I, Putz EM, Hoermann G, Schuster C, Fajmann S, Leitner E, Kubicek S, Moriggl R, Gouilleux F, Sexl V. Berger A, et al. Leukemia. 2014 Mar;28(3):629-41. doi: 10.1038/leu.2013.351. Epub 2013 Nov 22. Leukemia. 2014. PMID: 24263804 Free PMC article.
In cultured bone marrow cells, expression of a STAT5 mutant lacking the S725 and S779 phosphorylation sites (STAT5(SASA)) prohibits transformation and induces apoptosis. ...Interfering with STAT5 phosphorylation could thus be a novel therapeutic approach to target B …
In cultured bone marrow cells, expression of a STAT5 mutant lacking the S725 and S779 phosphorylation sites (STAT5(SASA)) prohibits t …
CD74 regulates complexity of tumor cell HLA class II peptidome in brain metastasis and is a positive prognostic marker for patient survival.
Zeiner PS, Zinke J, Kowalewski DJ, Bernatz S, Tichy J, Ronellenfitsch MW, Thorsen F, Berger A, Forster MT, Muller A, Steinbach JP, Beschorner R, Wischhusen J, Kvasnicka HM, Plate KH, Stefanović S, Weide B, Mittelbronn M, Harter PN. Zeiner PS, et al. Acta Neuropathol Commun. 2018 Mar 1;6(1):18. doi: 10.1186/s40478-018-0521-5. Acta Neuropathol Commun. 2018. PMID: 29490700 Free PMC article.
We analyzed the effects of a siRNA mediated CD74 knockdown on HLA-expression and HLA peptidome composition in a brain metastatic melanoma cell line.We observed that CD74 expression on tumor cells is a strong positive prognostic marker in brain metastasis pati …
We analyzed the effects of a siRNA mediated CD74 knockdown on HLA-expression and HLA peptidome composition in a brain metastat …
In vivo BiFC analysis of Y14 and NXF1 mRNA export complexes: preferential localization within and around SC35 domains.
Schmidt U, Richter K, Berger AB, Lichter P. Schmidt U, et al. J Cell Biol. 2006 Jan 30;172(3):373-81. doi: 10.1083/jcb.200503061. Epub 2006 Jan 23. J Cell Biol. 2006. PMID: 16431928 Free PMC article.
These results suggest that a fraction of RNA, which remains in the nucleus for several hours despite its association with splicing and export proteins, accumulates in speckles because of an ATP-dependent mechanism....
These results suggest that a fraction of RNA, which remains in the nucleus for several hours despite its association with splicing an …
Inability to obtain sperm for fresh IVF cycles: analysis and incidence of outcomes using a database from the United States.
Berger AJ, Raup V, Abou Ghayda R, Lanes A, Kathrins M. Berger AJ, et al. Fertil Res Pract. 2020 Aug 11;6:14. doi: 10.1186/s40738-020-00082-3. eCollection 2020. Fertil Res Pract. 2020. PMID: 32793376 Free PMC article.
A Review of Patisiran (ONPATTRO®) for the Treatment of Polyneuropathy in People with Hereditary Transthyretin Amyloidosis.
Urits I, Swanson D, Swett MC, Patel A, Berardino K, Amgalan A, Berger AA, Kassem H, Kaye A, Viswanath O. Urits I, et al. Among authors: berger aa. Neurol Ther. 2020 Aug 12. doi: 10.1007/s40120-020-00208-1. Online ahead of print. Neurol Ther. 2020. PMID: 32785879 Review.
Margin-Positive Pancreatic Ductal Adenocarcinoma during Pancreaticoduodenectomy: Additional Resection Does Not Improve Survival.
Zheng R, Nauheim D, Bassig J, Chadwick M, Schultz CW, Krampitz G, Lavu H, Winter JR, Yeo CJ, Berger AC. Zheng R, et al. Among authors: berger ac. Ann Surg Oncol. 2020 Aug 10. doi: 10.1245/s10434-020-09000-9. Online ahead of print. Ann Surg Oncol. 2020. PMID: 32779052
Effectiveness of a dedicated small bowel neoplasia screening program by capsule endoscopy in Lynch syndrome: 5 years results from a tertiary care center.
Perrod G, Samaha E, Perez-Cuadrado-Robles E, Berger A, Benosman H, Khater S, Vienne A, Cuenod CA, Zaanan A, Laurent-Puig P, Rahmi G, Cellier C. Perrod G, et al. Among authors: berger a. Therap Adv Gastroenterol. 2020 Jul 29;13:1756284820934314. doi: 10.1177/1756284820934314. eCollection 2020. Therap Adv Gastroenterol. 2020. PMID: 32774463 Free PMC article.
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