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Female rats are less prone to clinical heart failure than male rats in a juvenile rat model of right ventricular pressure load.
Bossers GPL, Hagdorn QAJ, Koop AC, van der Feen DE, Bartelds B, van Leusden T, De Boer RA, Silljé HHW, Berger RMF. Bossers GPL, et al. Among authors: berger rmf. Am J Physiol Heart Circ Physiol. 2022 Jun 1;322(6):H994-H1002. doi: 10.1152/ajpheart.00071.2022. Epub 2022 Mar 25. Am J Physiol Heart Circ Physiol. 2022. PMID: 35333114
CeRebrUm and CardIac Protection with ALlopurinol in Neonates with Critical Congenital Heart Disease Requiring Cardiac Surgery with Cardiopulmonary Bypass (CRUCIAL): study protocol of a phase III, randomized, quadruple-blinded, placebo-controlled, Dutch multicenter trial.
Stegeman R, Nijman M, Breur JMPJ, Groenendaal F, Haas F, Derks JB, Nijman J, van Beynum IM, Taverne YJHJ, Bogers AJJC, Helbing WA, de Boode WP, Bos AF, Berger RMF, Accord RE, Roes KCB, de Wit GA, Jansen NJG, Benders MJNL; CRUCIAL trial consortium. Stegeman R, et al. Among authors: berger rmf. Trials. 2022 Feb 23;23(1):174. doi: 10.1186/s13063-022-06098-y. Trials. 2022. PMID: 35197082 Free PMC article.
Neuregulin-1 enhances cell-cycle activity, delays cardiac fibrosis, and improves cardiac performance in rat pups with right ventricular pressure load.
Bossers GPL, Günthel M, van der Feen DE, Hagdorn QAJ, Koop AC, van Duijvenboden K, Barnett P, Borgdorff MAJ, Christoffels VM, Silljé HHW, Berger RMF, Bartelds B. Bossers GPL, et al. Among authors: berger rmf. J Thorac Cardiovasc Surg. 2021 Nov 3:S0022-5223(21)01520-8. doi: 10.1016/j.jtcvs.2021.10.045. Online ahead of print. J Thorac Cardiovasc Surg. 2021. PMID: 34922752 Free article.
The adult heart requires baseline expression of the transcription factor Hand2 to withstand RV pressure overload.
Videira RF, Koop AMC, Ottaviani L, Poels EM, Kocken JMM, Dos Remedios C, Mendes-Ferreira P, Van De Kolk KW, Du Marchie Sarvaas GJ, Lourenço A, Llucià-Valldeperas A, Nascimento DS, de Windt LJ, De Man FS, Falcão-Pires I, Berger RMF, da Costa Martins P. Videira RF, et al. Among authors: berger rmf. Cardiovasc Res. 2021 Sep 22:cvab299. doi: 10.1093/cvr/cvab299. Online ahead of print. Cardiovasc Res. 2021. PMID: 34550326
242 results