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In prostate cancer needle biopsies, detections of PTEN loss by fluorescence in situ hybridization (FISH) and by immunohistochemistry (IHC) are concordant and show consistent association with upgrading.
Picanço-Albuquerque CG, Morais CL, Carvalho FL, Peskoe SB, Hicks JL, Ludkovski O, Vidotto T, Fedor H, Humphreys E, Han M, Platz EA, De Marzo AM, Berman DM, Lotan TL, Squire JA. Picanço-Albuquerque CG, et al. Among authors: berman dm. Virchows Arch. 2016 May;468(5):607-17. doi: 10.1007/s00428-016-1904-2. Epub 2016 Feb 9. Virchows Arch. 2016. PMID: 26861919
Clinical implications of PTEN loss in prostate cancer.
Jamaspishvili T, Berman DM, Ross AE, Scher HI, De Marzo AM, Squire JA, Lotan TL. Jamaspishvili T, et al. Among authors: berman dm. Nat Rev Urol. 2018 Apr;15(4):222-234. doi: 10.1038/nrurol.2018.9. Epub 2018 Feb 20. Nat Rev Urol. 2018. PMID: 29460925 Free PMC article. Review.
High throughput assessment of biomarkers in tissue microarrays using artificial intelligence: PTEN loss as a proof-of-principle in multi-center prostate cancer cohorts.
Harmon SA, Patel PG, Sanford TH, Caven I, Iseman R, Vidotto T, Picanço C, Squire JA, Masoudi S, Mehralivand S, Choyke PL, Berman DM, Turkbey B, Jamaspishvili T. Harmon SA, et al. Among authors: berman dm. Mod Pathol. 2021 Feb;34(2):478-489. doi: 10.1038/s41379-020-00674-w. Epub 2020 Sep 3. Mod Pathol. 2021. PMID: 32884130 Free PMC article.
Risk Stratification of Prostate Cancer Through Quantitative Assessment of PTEN Loss (qPTEN).
Jamaspishvili T, Patel PG, Niu Y, Vidotto T, Caven I, Livergant R, Fu W, Kawashima A, How N, Okello JB, Guedes LB, Ouellet V, Picanço C, Koti M, Reis RB, Saad F, Mes-Masson AM, Lotan TL, Squire JA, Peng YP, Siemens DR, Berman DM. Jamaspishvili T, et al. Among authors: berman dm. J Natl Cancer Inst. 2020 Nov 1;112(11):1098-1104. doi: 10.1093/jnci/djaa032. J Natl Cancer Inst. 2020. PMID: 32129857 Free PMC article.
Notch signaling in prostate cancer: a moving target.
Carvalho FL, Simons BW, Eberhart CG, Berman DM. Carvalho FL, et al. Among authors: berman dm. Prostate. 2014 Jun;74(9):933-45. doi: 10.1002/pros.22811. Epub 2014 Apr 16. Prostate. 2014. PMID: 24737393 Free PMC article. Review.
PTEN-deficient prostate cancer is associated with an immunosuppressive tumor microenvironment mediated by increased expression of IDO1 and infiltrating FoxP3+ T regulatory cells.
Vidotto T, Saggioro FP, Jamaspishvili T, Chesca DL, Picanço de Albuquerque CG, Reis RB, Graham CH, Berman DM, Siemens DR, Squire JA, Koti M. Vidotto T, et al. Among authors: berman dm. Prostate. 2019 Jun;79(9):969-979. doi: 10.1002/pros.23808. Epub 2019 Apr 18. Prostate. 2019. PMID: 30999388
PI3K/mTOR signaling regulates prostatic branching morphogenesis.
Ghosh S, Lau H, Simons BW, Powell JD, Meyers DJ, De Marzo AM, Berman DM, Lotan TL. Ghosh S, et al. Among authors: berman dm. Dev Biol. 2011 Dec 15;360(2):329-42. doi: 10.1016/j.ydbio.2011.09.027. Epub 2011 Oct 8. Dev Biol. 2011. PMID: 22015718 Free PMC article.
Secreted protein, acidic and rich in cysteine-like 1 (SPARCL1) is down regulated in aggressive prostate cancers and is prognostic for poor clinical outcome.
Hurley PJ, Marchionni L, Simons BW, Ross AE, Peskoe SB, Miller RM, Erho N, Vergara IA, Ghadessi M, Huang Z, Gurel B, Park BH, Davicioni E, Jenkins RB, Platz EA, Berman DM, Schaeffer EM. Hurley PJ, et al. Among authors: berman dm. Proc Natl Acad Sci U S A. 2012 Sep 11;109(37):14977-82. doi: 10.1073/pnas.1203525109. Epub 2012 Aug 27. Proc Natl Acad Sci U S A. 2012. PMID: 22927397 Free PMC article.
Tumorigenic potential of circulating prostate tumor cells.
Carvalho FL, Simons BW, Antonarakis ES, Rasheed Z, Douglas N, Villegas D, Matsui W, Berman DM. Carvalho FL, et al. Among authors: berman dm. Oncotarget. 2013 Mar;4(3):413-21. doi: 10.18632/oncotarget.895. Oncotarget. 2013. PMID: 23530114 Free PMC article.
209 results