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78 results
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Islet beta cell expression of constitutively active Akt1/PKB alpha induces striking hypertrophy, hyperplasia, and hyperinsulinemia.
Bernal-Mizrachi E, Wen W, Stahlhut S, Welling CM, Permutt MA. Bernal-Mizrachi E, et al. J Clin Invest. 2001 Dec;108(11):1631-8. doi: 10.1172/JCI13785. J Clin Invest. 2001. PMID: 11733558 Free PMC article.
Activation of serum response factor in the depolarization induction of Egr-1 transcription in pancreatic islet beta-cells.
Bernal-Mizrachi E, Wice B, Inoue H, Permutt MA. Bernal-Mizrachi E, et al. J Biol Chem. 2000 Aug 18;275(33):25681-9. doi: 10.1074/jbc.M003424200. J Biol Chem. 2000. PMID: 10829028
Calpain 10: the first positional cloning of a gene for type 2 diabetes?
Permutt MA, Bernal-Mizrachi E, Inoue H. Permutt MA, et al. J Clin Invest. 2000 Oct;106(7):819-21. doi: 10.1172/JCI11228. J Clin Invest. 2000. PMID: 11018067 Free PMC article. No abstract available.
Glucose and other insulin secretagogues induce, rather than inhibit, expression of Id-1 and Id-3 in pancreatic islet beta cells.
Wice BM, Bernal-Mizrachi E, Permutt MA. Wice BM, et al. Diabetologia. 2001 Apr;44(4):453-63. doi: 10.1007/s001250051643. Diabetologia. 2001. PMID: 11357476
Activation of Elk-1, an Ets transcription factor, by glucose and EGF treatment of insulinoma cells.
Bernal-Mizrachi E, Wen W, Srinivasan S, Klenk A, Cohen D, Permutt MA. Bernal-Mizrachi E, et al. Am J Physiol Endocrinol Metab. 2001 Dec;281(6):E1286-99. doi: 10.1152/ajpendo.2001.281.6.E1286. Am J Physiol Endocrinol Metab. 2001. PMID: 11701445
Glucose promotes pancreatic islet beta-cell survival through a PI 3-kinase/Akt-signaling pathway.
Srinivasan S, Bernal-Mizrachi E, Ohsugi M, Permutt MA. Srinivasan S, et al. Am J Physiol Endocrinol Metab. 2002 Oct;283(4):E784-93. doi: 10.1152/ajpendo.00177.2002. Am J Physiol Endocrinol Metab. 2002. PMID: 12217896
Activation of nuclear factor-kappaB by depolarization and Ca(2+) influx in MIN6 insulinoma cells.
Bernal-Mizrachi E, Wen W, Shornick M, Permutt MA. Bernal-Mizrachi E, et al. Diabetes. 2002 Dec;51 Suppl 3:S484-8. doi: 10.2337/diabetes.51.2007.s484. Diabetes. 2002. PMID: 12475794
Gene expression profiling in islet biology and diabetes research.
Bernal-Mizrachi E, Cras-Méneur C, Ohsugi M, Permutt MA. Bernal-Mizrachi E, et al. Diabetes Metab Res Rev. 2003 Jan-Feb;19(1):32-42. doi: 10.1002/dmrr.331. Diabetes Metab Res Rev. 2003. PMID: 12592642 Review.
An expression profile of human pancreatic islet mRNAs by Serial Analysis of Gene Expression (SAGE).
Cras-Méneur C, Inoue H, Zhou Y, Ohsugi M, Bernal-Mizrachi E, Pape D, Clifton SW, Permutt MA. Cras-Méneur C, et al. Diabetologia. 2004 Feb;47(2):284-99. doi: 10.1007/s00125-003-1300-8. Epub 2004 Jan 13. Diabetologia. 2004. PMID: 14722648
Glucose and insulin treatment of insulinoma cells results in transcriptional regulation of a common set of genes.
Ohsugi M, Cras-Méneur C, Zhou Y, Warren W, Bernal-Mizrachi E, Permutt MA. Ohsugi M, et al. Diabetes. 2004 Jun;53(6):1496-508. doi: 10.2337/diabetes.53.6.1496. Diabetes. 2004. PMID: 15161754
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