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Novel NAPRT specific antibody identifies small cell lung cancer and neuronal cancers as promising clinical indications for a NAMPT inhibitor/niacin co-administration strategy.

Cole J, Guiot MC, Gravel M, Bernier C, Shore GC, Roulston A. Cole J, et al. Among authors: bernier c. Oncotarget. 2017 Sep 12;8(44):77846-77859. doi: 10.18632/oncotarget.20840. eCollection 2017 Sep 29. Oncotarget. 2017. PMID: 29100430 Free PMC article.

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DZ-2384 has a superior preclinical profile to taxanes for the treatment of triple-negative breast cancer and is synergistic with anti-CTLA-4 immunotherapy.

Bernier C, Soliman A, Gravel M, Dankner M, Savage P, Petrecca K, Park M, Siegel PM, Shore GC, Roulston A. Bernier C, et al. Anticancer Drugs. 2018 Sep;29(8):774-785. doi: 10.1097/CAD.0000000000000653. Anticancer Drugs. 2018. PMID: 29878901 Free PMC article.

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The synthetic diazonamide DZ-2384 has distinct effects on microtubule curvature and dynamics without neurotoxicity.

Wieczorek M, Tcherkezian J, Bernier C, Prota AE, Chaaban S, Rolland Y, Godbout C, Hancock MA, Arezzo JC, Ocal O, Rocha C, Olieric N, Hall A, Ding H, Bramoullé A, Annis MG, Zogopoulos G, Harran PG, Wilkie TM, Brekken RA, Siegel PM, Steinmetz MO, Shore GC, Brouhard GJ, Roulston A. Wieczorek M, et al. Among authors: bernier c. Sci Transl Med. 2016 Nov 16;8(365):365ra159. doi: 10.1126/scitranslmed.aag1093. Sci Transl Med. 2016. PMID: 27856798 Free PMC article.

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Obatoclax is a direct and potent antagonist of membrane-restricted Mcl-1 and is synthetic lethal with treatment that induces Bim.

Nguyen M, Cencic R, Ertel F, Bernier C, Pelletier J, Roulston A, Silvius JR, Shore GC. Nguyen M, et al. Among authors: bernier c. BMC Cancer. 2015 Aug 1;15:568. doi: 10.1186/s12885-015-1582-5. BMC Cancer. 2015. PMID: 26231047 Free PMC article.

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Preclinical development of the nicotinamide phosphoribosyl transferase inhibitor prodrug GMX1777.

Beauparlant P, Bédard D, Bernier C, Chan H, Gilbert K, Goulet D, Gratton MO, Lavoie M, Roulston A, Turcotte E, Watson M. Beauparlant P, et al. Among authors: bernier c. Anticancer Drugs. 2009 Jun;20(5):346-54. doi: 10.1097/CAD.0b013e3283287c20. Anticancer Drugs. 2009. PMID: 19369827

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The small molecule GMX1778 is a potent inhibitor of NAD+ biosynthesis: strategy for enhanced therapy in nicotinic acid phosphoribosyltransferase 1-deficient tumors.

Watson M, Roulston A, Bélec L, Billot X, Marcellus R, Bédard D, Bernier C, Branchaud S, Chan H, Dairi K, Gilbert K, Goulet D, Gratton MO, Isakau H, Jang A, Khadir A, Koch E, Lavoie M, Lawless M, Nguyen M, Paquette D, Turcotte E, Berger A, Mitchell M, Shore GC, Beauparlant P. Watson M, et al. Among authors: bernier c. Mol Cell Biol. 2009 Nov;29(21):5872-88. doi: 10.1128/MCB.00112-09. Epub 2009 Aug 24. Mol Cell Biol. 2009. PMID: 19703994 Free PMC article.

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Delayed eczematous skin reaction as an adverse drug reaction to immunoglobulin infusions: A case series.

Barthel C, Musquer M, Veyrac G, Bernier C. Barthel C, et al. Among authors: bernier c. Ann Dermatol Venereol. 2022 Jun 23:S0151-9638(22)00056-4. doi: 10.1016/j.annder.2022.05.002. Online ahead of print. Ann Dermatol Venereol. 2022. PMID: 35753818

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How best can faculty development support teachers in clinical settings?

Gagnon N, Bernier C, Houde S. Gagnon N, et al. Among authors: bernier c. Br J Hosp Med (Lond). 2022 May 2;83(5):1-8. doi: 10.12968/hmed.2021.0671. Epub 2022 May 6. Br J Hosp Med (Lond). 2022. PMID: 35653319

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Doxycycline versus azithromycin for the treatment of anorectal Chlamydia trachomatis infection in women concurrent with vaginal infection (CHLAZIDOXY study): a multicentre, open-label, randomised, controlled, superiority trial.

Peuchant O, Lhomme E, Martinet P, Grob A, Baïta D, Bernier C, Gibaud SA, Le Hen I, Le Naour E, Trignol-Viguier N, Lanotte P, Lefebvre P, Vachée A, Girard T, Loubinoux J, Bébéar C, Ghezzoul B, Roussillon C, Kret M, de Barbeyrac B; CHLAZIDOXY Study Group. Peuchant O, et al. Among authors: bernier c. Lancet Infect Dis. 2022 May 9:S1473-3099(22)00148-7. doi: 10.1016/S1473-3099(22)00148-7. Online ahead of print. Lancet Infect Dis. 2022. PMID: 35550262

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Longer Dupilumab Dosing Intervals in Adult Patients with Atopic Dermatitis: Experience from a French Multicentre Retrospective Cohort Study.

Jendoubi F, Shourik J, Seneschal J, Giordano-Labadie F, Raison-Peyron N, Du-Thanh A, Tetart F, Valois A, Droitcourt C, Clément A, Nosbaum A, Crepy MN, Jachiet M, Bouaziz JD, Bernier C, Soria A, Paul C, Barbarot S, Tauber M; GREAT network (Groupe de Recherche sur l’Eczema ATopique of the French Society of Dermatology). Jendoubi F, et al. Among authors: bernier c. Br J Dermatol. 2022 Apr 28. doi: 10.1111/bjd.21628. Online ahead of print. Br J Dermatol. 2022. PMID: 35481677 No abstract available.

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