Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

My NCBI Filters
Text availability
Article attribute
Article type
Publication date

Search Results

373 results
Filters applied: . Clear all Results are displayed in a computed author sort order. Results by year timeline is unavailable
Page 1
Developmental rescue of an embryonic-lethal mutation in the retinoblastoma gene in chimeric mice.
Maandag EC, van der Valk M, Vlaar M, Feltkamp C, O'Brien J, van Roon M, van der Lugt N, Berns A, te Riele H. Maandag EC, et al. EMBO J. 1994 Sep 15;13(18):4260-8. EMBO J. 1994. PMID: 7925271 Free PMC article.
The requirement for a functional retinoblastoma gene, Rb-1, in murine development around days 12-15 of gestation precludes monitoring the effect of loss of Rb-1 function on later stages of development and on tumorigenesis in adult mice. ...
The requirement for a functional retinoblastoma gene, Rb-1, in murine development around days 12-15 of gestation precludes monitoring …
T cell receptor-alpha beta lacking the beta-chain V domain can be expressed at the cell surface but prohibits T cell maturation.
Ossendorp F, Jacobs H, van der Horst G, de Vries E, Berns A, Borst J. Ossendorp F, et al. J Immunol. 1992 Jun 15;148(12):3714-22. J Immunol. 1992. PMID: 1351085
A TCR-beta gene lacking V domain sequences (delta V-TCR-beta) was inserted into the germline of mice. Expression of the transgene inhibited endogenous TCR-beta, but not TCR-alpha gene rearrangement and expression. ...To help understand these effects on TCR-beta gene rearra
A TCR-beta gene lacking V domain sequences (delta V-TCR-beta) was inserted into the germline of mice. Expression of the transgene inh
Highly efficient gene targeting in embryonic stem cells through homologous recombination with isogenic DNA constructs.
te Riele H, Maandag ER, Berns A. te Riele H, et al. Proc Natl Acad Sci U S A. 1992 Jun 1;89(11):5128-32. doi: 10.1073/pnas.89.11.5128. Proc Natl Acad Sci U S A. 1992. PMID: 1594621 Free PMC article.
Homologous recombination at the retinoblastoma susceptibility gene (Rb) in embryonic stem cells derived from mouse strain 129 was 20-fold more efficient with a 129-derived targeting construct than with a BALB/c-derived construct. The two constructs were identical, e …
Homologous recombination at the retinoblastoma susceptibility gene (Rb) in embryonic stem cells derived from mouse strain 129 was 20-fold mo …
Tumorigenesis in transgenic mice: identification and characterization of synergizing oncogenes.
Berns A. Berns A. J Cell Biochem. 1991 Oct;47(2):130-5. doi: 10.1002/jcb.240470206. J Cell Biochem. 1991. PMID: 1661736 Review.
Transgenic mice carrying oncogenes present a useful model with which to assess the tissue-specific action of oncogenes. These mice are usually predisposed to a specific type of neoplastic growth. ...A strong acceleration of tumor induction ensued upon infecti …
Transgenic mice carrying oncogenes present a useful model with which to assess the tissue-specific action of oncogenes. These mice ar …
The pim-1 oncogene encodes two related protein-serine/threonine kinases by alternative initiation at AUG and CUG.
Saris CJ, Domen J, Berns A. Saris CJ, et al. EMBO J. 1991 Mar;10(3):655-64. EMBO J. 1991. PMID: 1825810 Free PMC article.
The pim-1 cDNA sequence predicts that both murine and human pim-1 encode a 34 kd protein with homology to protein kinases. In this study, we show that the murine pim-1 gene encodes a 44 kd protein in addition to the predicted 34 kd protein. ...
The pim-1 cDNA sequence predicts that both murine and human pim-1 encode a 34 kd protein with homology to protein kinases. In this st …
A pgk::hprt fusion as a selectable marker for targeting of genes in mouse embryonic stem cells: disruption of the T-cell receptor delta-chain-encoding gene.
van der Lugt N, Maandag ER, te Riele H, Laird PW, Berns A. van der Lugt N, et al. Gene. 1991 Sep 15;105(2):263-7. doi: 10.1016/0378-1119(91)90161-4. Gene. 1991. PMID: 1834524
We have constructed a hypoxanthine phosphoribosyl transferase-selectable marker (hprt) under the control of the phosphoglycerate kinase (pgk) promoter. ...
We have constructed a hypoxanthine phosphoribosyl transferase-selectable marker (hprt) under the control of the phosphoglycerate kina …
Identification of cooperating oncogenes in E mu-myc transgenic mice by provirus tagging.
van Lohuizen M, Verbeek S, Scheijen B, Wientjens E, van der Gulden H, Berns A. van Lohuizen M, et al. Cell. 1991 May 31;65(5):737-52. doi: 10.1016/0092-8674(91)90382-9. Cell. 1991. PMID: 1904008
Mo-MLV infection of E mu-myc transgenic mice results in a dramatic acceleration of pre-B cell lymphomagenesis. We have used provirus tagging to identify genes that cooperate with the E mu-myc transgene in B cell transformation. ...The bmi-1 gene encodes a 324 amino …
Mo-MLV infection of E mu-myc transgenic mice results in a dramatic acceleration of pre-B cell lymphomagenesis. We have used provirus …
Sequence similarity between the mammalian bmi-1 proto-oncogene and the Drosophila regulatory genes Psc and Su(z)2.
van Lohuizen M, Frasch M, Wientjens E, Berns A. van Lohuizen M, et al. Nature. 1991 Sep 26;353(6342):353-5. doi: 10.1038/353353a0. Nature. 1991. PMID: 1922340
It encodes a highly conserved nuclear protein of 324 amino acids which belongs to a family of proteins containing a putative new zinc-finger. ...Here we report on the cloning and characterization of a homologous gene (D-bmi) from Drosophila melanogaste …
It encodes a highly conserved nuclear protein of 324 amino acids which belongs to a family of proteins containing a put …
Carcinogen-induced lymphomagenesis in pim-1 transgenic mice: dose dependence and involvement of myc and ras.
Breuer M, Wientjens E, Verbeek S, Slebos R, Berns A. Breuer M, et al. Cancer Res. 1991 Feb 1;51(3):958-63. Cancer Res. 1991. PMID: 1988138
Here we describe the incidence of tumors as a function of the dose of ENU. Either 200, 15, 4, 1, or 0.1 mg/kg ENU was injected into transgenic and control mice and the tumor incidence was monitored. ...In most tumors the expression of c-myc was strongly elevated, probably …
Here we describe the incidence of tumors as a function of the dose of ENU. Either 200, 15, 4, 1, or 0.1 mg/kg ENU was injected into t …
Mice bearing the E mu-myc and E mu-pim-1 transgenes develop pre-B-cell leukemia prenatally.
Verbeek S, van Lohuizen M, van der Valk M, Domen J, Kraal G, Berns A. Verbeek S, et al. Mol Cell Biol. 1991 Feb;11(2):1176-9. doi: 10.1128/mcb.11.2.1176. Mol Cell Biol. 1991. PMID: 1990273 Free PMC article.
373 results
Jump to page
Feedback