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Conferring substrate specificity to DNA helicases: role of the RecQ HRDC domain.
Bernstein DA, Keck JL. Bernstein DA, et al. Structure. 2005 Aug;13(8):1173-82. doi: 10.1016/j.str.2005.04.018. Structure. 2005. PMID: 16084389
The HRDC domain of BLM is required for the dissolution of double Holliday junctions.
Wu L, Chan KL, Ralf C, Bernstein DA, Garcia PL, Bohr VA, Vindigni A, Janscak P, Keck JL, Hickson ID. Wu L, et al. Among authors: bernstein da. EMBO J. 2005 Jul 20;24(14):2679-87. doi: 10.1038/sj.emboj.7600740. Epub 2005 Jun 30. EMBO J. 2005. PMID: 15990871 Free PMC article.
Small-molecule tools for dissecting the roles of SSB/protein interactions in genome maintenance.
Lu D, Bernstein DA, Satyshur KA, Keck JL. Lu D, et al. Among authors: bernstein da. Proc Natl Acad Sci U S A. 2010 Jan 12;107(2):633-8. doi: 10.1073/pnas.0909191107. Epub 2009 Dec 16. Proc Natl Acad Sci U S A. 2010. PMID: 20018747 Free PMC article.
A central role for SSB in Escherichia coli RecQ DNA helicase function.
Shereda RD, Bernstein DA, Keck JL. Shereda RD, et al. Among authors: bernstein da. J Biol Chem. 2007 Jun 29;282(26):19247-58. doi: 10.1074/jbc.M608011200. Epub 2007 May 3. J Biol Chem. 2007. PMID: 17483090
Structure of the calcium-rich signature domain of human thrombospondin-2.
Carlson CB, Bernstein DA, Annis DS, Misenheimer TM, Hannah BL, Mosher DF, Keck JL. Carlson CB, et al. Among authors: bernstein da. Nat Struct Mol Biol. 2005 Oct;12(10):910-4. doi: 10.1038/nsmb997. Epub 2005 Sep 25. Nat Struct Mol Biol. 2005. PMID: 16186819 Free PMC article.
Structural basis of the Sir1-origin recognition complex interaction in transcriptional silencing.
Hou Z, Bernstein DA, Fox CA, Keck JL. Hou Z, et al. Among authors: bernstein da. Proc Natl Acad Sci U S A. 2005 Jun 14;102(24):8489-94. doi: 10.1073/pnas.0503525102. Epub 2005 Jun 2. Proc Natl Acad Sci U S A. 2005. PMID: 15932939 Free PMC article.
Crystal structure of the Deinococcus radiodurans single-stranded DNA-binding protein suggests a mechanism for coping with DNA damage.
Bernstein DA, Eggington JM, Killoran MP, Misic AM, Cox MM, Keck JL. Bernstein DA, et al. Proc Natl Acad Sci U S A. 2004 Jun 8;101(23):8575-80. doi: 10.1073/pnas.0401331101. Epub 2004 May 24. Proc Natl Acad Sci U S A. 2004. PMID: 15159541 Free PMC article.
Domain mapping of Escherichia coli RecQ defines the roles of conserved N- and C-terminal regions in the RecQ family.
Bernstein DA, Keck JL. Bernstein DA, et al. Nucleic Acids Res. 2003 Jun 1;31(11):2778-85. doi: 10.1093/nar/gkg376. Nucleic Acids Res. 2003. PMID: 12771204 Free PMC article.
High-resolution structure of the E.coli RecQ helicase catalytic core.
Bernstein DA, Zittel MC, Keck JL. Bernstein DA, et al. EMBO J. 2003 Oct 1;22(19):4910-21. doi: 10.1093/emboj/cdg500. EMBO J. 2003. PMID: 14517231 Free PMC article.
Protein interactions in genome maintenance as novel antibacterial targets.
Marceau AH, Bernstein DA, Walsh BW, Shapiro W, Simmons LA, Keck JL. Marceau AH, et al. Among authors: bernstein da. PLoS One. 2013;8(3):e58765. doi: 10.1371/journal.pone.0058765. Epub 2013 Mar 11. PLoS One. 2013. PMID: 23536821 Free PMC article.
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