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Pharmacokinetics and ADME Characterization of Intravenous and Oral [14C]-Linerixibat in Healthy Male Volunteers.
Drug Metab Dispos. 2021 Dec;49(12):1109-1117. doi: 10.1124/dmd.121.000595. Epub 2021 Oct 8.
Drug Metab Dispos. 2021.
PMID: 34625435
Clinical Trial.
Metabolism and disposition of oral dabrafenib in cancer patients: proposed participation of aryl nitrogen in carbon-carbon bond cleavage via decarboxylation following enzymatic oxidation.
Bershas DA, Ouellet D, Mamaril-Fishman DB, Nebot N, Carson SW, Blackman SC, Morrison RA, Adams JL, Jurusik KE, Knecht DM, Gorycki PD, Richards-Peterson LE.
Bershas DA, et al.
Drug Metab Dispos. 2013 Dec;41(12):2215-24. doi: 10.1124/dmd.113.053785. Epub 2013 Oct 4.
Drug Metab Dispos. 2013.
PMID: 24097902
Clinical Trial.
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Bioavailability, metabolism and disposition of oral pazopanib in patients with advanced cancer.
Deng Y, Sychterz C, Suttle AB, Dar MM, Bershas D, Negash K, Qian Y, Chen EP, Gorycki PD, Ho MY.
Deng Y, et al. Among authors: bershas d.
Xenobiotica. 2013 May;43(5):443-53. doi: 10.3109/00498254.2012.734642. Epub 2012 Nov 16.
Xenobiotica. 2013.
PMID: 23548165
Clinical Trial.
Item in Clipboard
Investigations of hydrazine cleavage of eltrombopag in humans.
Deng Y, Rogers M, Sychterz C, Talley K, Qian Y, Bershas D, Ho M, Shi W, Chen EP, Serabjit-Singh C, Gorycki PD.
Deng Y, et al. Among authors: bershas d.
Drug Metab Dispos. 2011 Sep;39(9):1747-54. doi: 10.1124/dmd.111.040188. Epub 2011 Jun 6.
Drug Metab Dispos. 2011.
PMID: 21646438
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Cyanide trapping of iminium ion reactive intermediates followed by detection and structure identification using liquid chromatography-tandem mass spectrometry (LC-MS/MS).
Argoti D, Liang L, Conteh A, Chen L, Bershas D, Yu CP, Vouros P, Yang E.
Argoti D, et al. Among authors: bershas d.
Chem Res Toxicol. 2005 Oct;18(10):1537-44. doi: 10.1021/tx0501637.
Chem Res Toxicol. 2005.
PMID: 16533017
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