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Page 1
Pharmacokinetics and ADME Characterization of Intravenous and Oral [14C]-Linerixibat in Healthy Male Volunteers.
Zamek-Gliszczynski MJ, Kenworthy D, Bershas DA, Sanghvi M, Pereira AI, Mudunuru J, Crossman L, Pirhalla JL, Thorpe KM, Dennison JMTJ, McLaughlin MM, Allinder M, Swift B, O'Connor-Semmes RL, Young GC. Zamek-Gliszczynski MJ, et al. Among authors: bershas da. Drug Metab Dispos. 2021 Dec;49(12):1109-1117. doi: 10.1124/dmd.121.000595. Epub 2021 Oct 8. Drug Metab Dispos. 2021. PMID: 34625435 Clinical Trial.
Metabolism and disposition of oral dabrafenib in cancer patients: proposed participation of aryl nitrogen in carbon-carbon bond cleavage via decarboxylation following enzymatic oxidation.
Bershas DA, Ouellet D, Mamaril-Fishman DB, Nebot N, Carson SW, Blackman SC, Morrison RA, Adams JL, Jurusik KE, Knecht DM, Gorycki PD, Richards-Peterson LE. Bershas DA, et al. Drug Metab Dispos. 2013 Dec;41(12):2215-24. doi: 10.1124/dmd.113.053785. Epub 2013 Oct 4. Drug Metab Dispos. 2013. PMID: 24097902 Clinical Trial.
Investigations of hydrazine cleavage of eltrombopag in humans.
Deng Y, Rogers M, Sychterz C, Talley K, Qian Y, Bershas D, Ho M, Shi W, Chen EP, Serabjit-Singh C, Gorycki PD. Deng Y, et al. Among authors: bershas d. Drug Metab Dispos. 2011 Sep;39(9):1747-54. doi: 10.1124/dmd.111.040188. Epub 2011 Jun 6. Drug Metab Dispos. 2011. PMID: 21646438