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A new synthesis of sulfonamides by aminolysis of p-nitrophenylsulfonates yielding potent and selective adenosine A2B receptor antagonists.
Yan L, Bertarelli DC, Hayallah AM, Meyer H, Klotz KN, Müller CE. Yan L, et al. Among authors: bertarelli dc. J Med Chem. 2006 Jul 13;49(14):4384-91. doi: 10.1021/jm060277v. J Med Chem. 2006. PMID: 16821798
Ligand-specific binding and activation of the human adenosine A(2B) receptor.
Thimm D, Schiedel AC, Sherbiny FF, Hinz S, Hochheiser K, Bertarelli DC, Maass A, Müller CE. Thimm D, et al. Among authors: bertarelli dc. Biochemistry. 2013 Jan 29;52(4):726-40. doi: 10.1021/bi3012065. Epub 2013 Jan 14. Biochemistry. 2013. PMID: 23286920
1-alkyl-8-(piperazine-1-sulfonyl)phenylxanthines: development and characterization of adenosine A2B receptor antagonists and a new radioligand with subnanomolar affinity and subtype specificity.
Borrmann T, Hinz S, Bertarelli DC, Li W, Florin NC, Scheiff AB, Müller CE. Borrmann T, et al. Among authors: bertarelli dc. J Med Chem. 2009 Jul 9;52(13):3994-4006. doi: 10.1021/jm900413e. J Med Chem. 2009. PMID: 19569717
Characterization of human and rodent native and recombinant adenosine A(2B) receptors by radioligand binding studies.
Bertarelli DC, Diekmann M, Hayallah AM, Rüsing D, Iqbal J, Preiss B, Verspohl EJ, Müller CE. Bertarelli DC, et al. Purinergic Signal. 2006 Sep;2(3):559-71. doi: 10.1007/s11302-006-9012-4. Epub 2006 Jul 8. Purinergic Signal. 2006. PMID: 18404493 Free PMC article.
Synthesis and pharmacology of pyrido[2,3-d]pyrimidinediones bearing polar substituents as adenosine receptor antagonists.
Bulicz J, Bertarelli DC, Baumert D, Fülle F, Müller CE, Heber D. Bulicz J, et al. Among authors: bertarelli dc. Bioorg Med Chem. 2006 Apr 15;14(8):2837-49. doi: 10.1016/j.bmc.2005.12.008. Epub 2006 Jan 11. Bioorg Med Chem. 2006. PMID: 16377196
Synthesis and preliminary evaluation of new 1- and 3-[1-(2-hydroxy-3-phenoxypropyl)]xanthines from 2-amino-2-oxazolines as potential A1 and A2A adenosine receptor antagonists.
Massip S, Guillon J, Bertarelli D, Bosc JJ, Léger JM, Lacher S, Bontemps C, Dupont T, Müller CE, Jarry C. Massip S, et al. Among authors: bertarelli d. Bioorg Med Chem. 2006 Apr 15;14(8):2697-719. doi: 10.1016/j.bmc.2005.11.050. Epub 2005 Dec 28. Bioorg Med Chem. 2006. PMID: 16386423
Response to Weingarten, "Methemoglobinemia in the setting of chronic transdermal lidocaine patch use," Pain Medicine 2012.
Wieman MS, Bertarelli DC, Brockbals C. Wieman MS, et al. Among authors: bertarelli dc. Pain Med. 2013 May;14(5):771. doi: 10.1111/pme.12119. Epub 2013 Apr 11. Pain Med. 2013. PMID: 23578070 No abstract available.
Metabotropic glutamate type 5, dopamine D2 and adenosine A2a receptors form higher-order oligomers in living cells.
Cabello N, Gandía J, Bertarelli DC, Watanabe M, Lluís C, Franco R, Ferré S, Luján R, Ciruela F. Cabello N, et al. Among authors: bertarelli dc. J Neurochem. 2009 Jun;109(5):1497-507. doi: 10.1111/j.1471-4159.2009.06078.x. Epub 2009 Mar 30. J Neurochem. 2009. PMID: 19344374 Free PMC article.