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Rescue of Hippo coactivator YAP1 triggers DNA damage-induced apoptosis in hematological cancers.
Cottini F, Hideshima T, Xu C, Sattler M, Dori M, Agnelli L, ten Hacken E, Bertilaccio MT, Antonini E, Neri A, Ponzoni M, Marcatti M, Richardson PG, Carrasco R, Kimmelman AC, Wong KK, Caligaris-Cappio F, Blandino G, Kuehl WM, Anderson KC, Tonon G. Cottini F, et al. Among authors: Bertilaccio MT. Nat Med. 2014 Jun;20(6):599-606. doi: 10.1038/nm.3562. Epub 2014 May 11. Nat Med. 2014. PMID: 24813251 Free PMC article.
Invariant NKT cells contribute to chronic lymphocytic leukemia surveillance and prognosis.
Gorini F, Azzimonti L, Delfanti G, Scarfò L, Scielzo C, Bertilaccio MT, Ranghetti P, Gulino A, Doglioni C, Di Napoli A, Capri M, Franceschi C, Caligaris-Cappio F, Ghia P, Bellone M, Dellabona P, Casorati G, de Lalla C. Gorini F, et al. Among authors: Bertilaccio MT. Blood. 2017 Jun 29;129(26):3440-3451. doi: 10.1182/blood-2016-11-751065. Epub 2017 May 2. Blood. 2017. PMID: 28465341
AMG-176, an Mcl-1 antagonist, shows preclinical efficacy in chronic lymphocytic leukemia.
Yi X, Sarkar A, Kismali G, Aslan B, Ayres M, Iles LR, Keating MJ, Wierda W, Long JP, Bertilaccio MTS, Gandhi V. Yi X, et al. Among authors: Bertilaccio MTS. Clin Cancer Res. 2020 Jan 14:clincanres.1397.2019. doi: 10.1158/1078-0432.CCR-19-1397. Online ahead of print. Clin Cancer Res. 2020. PMID: 31937611
Trabectedin Reveals a Strategy of Immunomodulation in Chronic Lymphocytic Leukemia.
Banerjee P, Zhang R, Ivan C, Galletti G, Clise-Dwyer K, Barbaglio F, Scarfò L, Aracil M, Klein C, Wierda W, Plunkett W, Caligaris-Cappio F, Gandhi V, Keating MJ, Bertilaccio MTS. Banerjee P, et al. Among authors: Bertilaccio MTS. Cancer Immunol Res. 2019 Dec;7(12):2036-2051. doi: 10.1158/2326-6066.CIR-19-0152. Epub 2019 Sep 17. Cancer Immunol Res. 2019. PMID: 31530560
The Interaction Between Two Worlds: MicroRNAs and Toll-Like Receptors.
Bayraktar R, Bertilaccio MTS, Calin GA. Bayraktar R, et al. Among authors: Bertilaccio MTS. Front Immunol. 2019 May 14;10:1053. doi: 10.3389/fimmu.2019.01053. eCollection 2019. Front Immunol. 2019. PMID: 31139186 Free PMC article. Review.
IL1R8 Deficiency Drives Autoimmunity-Associated Lymphoma Development.
Riva F, Ponzoni M, Supino D, Bertilaccio MTS, Polentarutti N, Massara M, Pasqualini F, Carriero R, Innocenzi A, Anselmo A, Veliz-Rodriguez T, Simonetti G, Anders HJ, Caligaris-Cappio F, Mantovani A, Muzio M, Garlanda C. Riva F, et al. Among authors: Bertilaccio MTS. Cancer Immunol Res. 2019 Jun;7(6):874-885. doi: 10.1158/2326-6066.CIR-18-0698. Epub 2019 Apr 24. Cancer Immunol Res. 2019. PMID: 31018956
The involvement of microRNA in the pathogenesis of Richter syndrome.
Van Roosbroeck K, Bayraktar R, Calin S, Bloehdorn J, Dragomir MP, Okubo K, Bertilaccio MTS, Zupo S, You MJ, Gaidano G, Rossi D, Chen SS, Chiorazzi N, Thompson PA, Ferrajoli A, Bertoni F, Stilgenbauer S, Keating MJ, Calin GA. Van Roosbroeck K, et al. Among authors: Bertilaccio MTS. Haematologica. 2019 May;104(5):1004-1015. doi: 10.3324/haematol.2018.203828. Epub 2018 Nov 8. Haematologica. 2019. PMID: 30409799 Free PMC article.
In Vitro Assay to Study CLL and Monocyte Interactions.
Bertilaccio MTS, Zhang R, Banerjee P, Gandhi V. Bertilaccio MTS, et al. Methods Mol Biol. 2019;1881:113-119. doi: 10.1007/978-1-4939-8876-1_9. Methods Mol Biol. 2019. PMID: 30350201
A retinoic acid-dependent stroma-leukemia crosstalk promotes chronic lymphocytic leukemia progression.
Farinello D, Wozińska M, Lenti E, Genovese L, Bianchessi S, Migliori E, Sacchetti N, di Lillo A, Bertilaccio MTS, de Lalla C, Valsecchi R, Gleave SB, Lligé D, Scielzo C, Mauri L, Ciampa MG, Scarfò L, Bernardi R, Lazarevic D, Gonzalez-Farre B, Bongiovanni L, Campo E, Cerutti A, Ponzoni M, Pattini L, Caligaris-Cappio F, Ghia P, Brendolan A. Farinello D, et al. Among authors: Bertilaccio MTS. Nat Commun. 2018 May 3;9(1):1787. doi: 10.1038/s41467-018-04150-7. Nat Commun. 2018. PMID: 29725010 Free PMC article.
Induction of iron excess restricts malignant plasma cells expansion and potentiates bortezomib effect in models of multiple myeloma.
Bordini J, Galvan S, Ponzoni M, Bertilaccio MT, Chesi M, Bergsagel PL, Camaschella C, Campanella A. Bordini J, et al. Among authors: Bertilaccio MT. Leukemia. 2017 Apr;31(4):967-970. doi: 10.1038/leu.2016.346. Epub 2016 Nov 24. Leukemia. 2017. PMID: 27881873 No abstract available.
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