Bertilsson L - Search Results

1

Cytochrome P450 induction by rifampicin in healthy subjects: determination using the Karolinska cocktail and the endogenous CYP3A4 marker 4beta-hydroxycholesterol.

Kanebratt KP, Diczfalusy U, Bäckström T, Sparve E, Bredberg E, Böttiger Y, Andersson TB, Bertilsson L. Kanebratt KP, et al. Among authors: bertilsson l. Clin Pharmacol Ther. 2008 Nov;84(5):589-94. doi: 10.1038/clpt.2008.132. Epub 2008 Jul 23. Clin Pharmacol Ther. 2008. PMID: 18650803 Clinical Trial.

2

Time course of the increase in 4beta-hydroxycholesterol concentration during carbamazepine treatment of paediatric patients with epilepsy.

Wide K, Larsson H, Bertilsson L, Diczfalusy U. Wide K, et al. Among authors: bertilsson l. Br J Clin Pharmacol. 2008 May;65(5):708-15. doi: 10.1111/j.1365-2125.2007.03078.x. Epub 2008 Feb 12. Br J Clin Pharmacol. 2008. PMID: 18279471 Free PMC article.

3

4beta-hydroxycholesterol as an endogenous marker for CYP3A4/5 activity. Stability and half-life of elimination after induction with rifampicin.

Diczfalusy U, Kanebratt KP, Bredberg E, Andersson TB, Böttiger Y, Bertilsson L. Diczfalusy U, et al. Among authors: bertilsson l. Br J Clin Pharmacol. 2009 Jan;67(1):38-43. doi: 10.1111/j.1365-2125.2008.03309.x. Epub 2008 Nov 6. Br J Clin Pharmacol. 2009. PMID: 19006545 Free PMC article.

4

4β-Hydroxycholesterol, an endogenous marker of CYP3A4/5 activity in humans.

Diczfalusy U, Nylén H, Elander P, Bertilsson L. Diczfalusy U, et al. Among authors: bertilsson l. Br J Clin Pharmacol. 2011 Feb;71(2):183-9. doi: 10.1111/j.1365-2125.2010.03773.x. Br J Clin Pharmacol. 2011. PMID: 21219398 Free PMC article. Review.

5

Comparison of endogenous 4β-hydroxycholesterol with midazolam as markers for CYP3A4 induction by rifampicin.

Björkhem-Bergman L, Bäckström T, Nylén H, Rönquist-Nii Y, Bredberg E, Andersson TB, Bertilsson L, Diczfalusy U. Björkhem-Bergman L, et al. Among authors: bertilsson l. Drug Metab Dispos. 2013 Aug;41(8):1488-93. doi: 10.1124/dmd.113.052316. Epub 2013 May 14. Drug Metab Dispos. 2013. PMID: 23674608 Clinical Trial.

6

Quinine compared to 4β-hydroxycholesterol and midazolam as markers for CYP3A induction by rifampicin.

Björkhem-Bergman L, Bäckström T, Nylén H, Rönquist-Nii Y, Bredberg E, Andersson TB, Bertilsson L, Diczfalusy U. Björkhem-Bergman L, et al. Among authors: bertilsson l. Drug Metab Pharmacokinet. 2014;29(4):352-5. doi: 10.2133/dmpk.dmpk-13-sh-138. Epub 2014 Feb 11. Drug Metab Pharmacokinet. 2014. PMID: 24522201 Free article. Clinical Trial.

7

Enantioselective hydroxylation of omeprazole catalyzed by CYP2C19 in Swedish white subjects.

Tybring G, Böttiger Y, Widén J, Bertilsson L. Tybring G, et al. Among authors: bertilsson l. Clin Pharmacol Ther. 1997 Aug;62(2):129-37. doi: 10.1016/S0009-9236(97)90060-6. Clin Pharmacol Ther. 1997. PMID: 9284848

8

Inhibition of the sulfoxidation of omeprazole by ketoconazole in poor and extensive metabolizers of S-mephenytoin.

Böttiger Y, Tybring G, Götharson E, Bertilsson L. Böttiger Y, et al. Among authors: bertilsson l. Clin Pharmacol Ther. 1997 Oct;62(4):384-91. doi: 10.1016/S0009-9236(97)90116-8. Clin Pharmacol Ther. 1997. PMID: 9357389

9

Tolterodine does not affect the human in vivo metabolism of the probe drugs caffeine, debrisoquine and omeprazole.

Brynne N, Böttiger Y, Hallén B, Bertilsson L. Brynne N, et al. Among authors: bertilsson l. Br J Clin Pharmacol. 1999 Feb;47(2):145-50. doi: 10.1046/j.1365-2125.1999.00865.x. Br J Clin Pharmacol. 1999. PMID: 10190648 Free PMC article. Clinical Trial.

10

CYP3A induction and inhibition by different antiretroviral regimens reflected by changes in plasma 4beta-hydroxycholesterol levels.

Josephson F, Bertilsson L, Böttiger Y, Flamholc L, Gisslén M, Ormaasen V, Sönnerborg A, Diczfalusy U. Josephson F, et al. Among authors: bertilsson l. Eur J Clin Pharmacol. 2008 Aug;64(8):775-81. doi: 10.1007/s00228-008-0492-8. Epub 2008 May 6. Eur J Clin Pharmacol. 2008. PMID: 18458892 Clinical Trial.

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