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Integrin signal transduction in myeloid leukocytes.
Lowell CA, Berton G. Lowell CA, et al. J Leukoc Biol. 1999 Mar;65(3):313-20. doi: 10.1002/jlb.65.3.313. J Leukoc Biol. 1999. PMID: 10080533 Review.
Integrin signalling in neutrophils and macrophages.
Berton G, Lowell CA. Berton G, et al. Cell Signal. 1999 Sep;11(9):621-35. doi: 10.1016/s0898-6568(99)00003-0. Cell Signal. 1999. PMID: 10530871 Review.
Role of Src kinases and Syk in Fcgamma receptor-mediated phagocytosis and phagosome-lysosome fusion.
Majeed M, Caveggion E, Lowell CA, Berton G. Majeed M, et al. J Leukoc Biol. 2001 Nov;70(5):801-11. J Leukoc Biol. 2001. PMID: 11698501
In this report we show that both wild-type and hck(-/-)fgr(-/-) macrophages expressed Fyn, Src, and Yes and that these kinases were activated on ingestion of immunoglobulin G (IgG)-coated particles and redistributed, together with Syk, to actin-rich phagocytic cups and the …
In this report we show that both wild-type and hck(-/-)fgr(-/-) macrophages expressed Fyn, Src, and Yes and that these kinases were activate …
Deficiency of Src family kinases p59/61hck and p58c-fgr results in defective adhesion-dependent neutrophil functions.
Lowell CA, Fumagalli L, Berton G. Lowell CA, et al. J Cell Biol. 1996 May;133(4):895-910. doi: 10.1083/jcb.133.4.895. J Cell Biol. 1996. PMID: 8666673 Free PMC article.
Fumagalli, and G Berton. 1995. J. Inflammation. 45:217-311.) To directly test whether these functional responses are dependent on the Src family kinases p59/61hck and p58c-fgr, we examined adhesion-dependent respiratory burst in PMNs isolated from hck -/-, fgr -/-, …
Fumagalli, and G Berton. 1995. J. Inflammation. 45:217-311.) To directly test whether these functional responses are dependent …
The Src family kinases Hck and Fgr are dispensable for inside-out, chemoattractant-induced signaling regulating beta 2 integrin affinity and valency in neutrophils, but are required for beta 2 integrin-mediated outside-in signaling involved in sustained adhesion.
Giagulli C, Ottoboni L, Caveggion E, Rossi B, Lowell C, Constantin G, Laudanna C, Berton G. Giagulli C, et al. J Immunol. 2006 Jul 1;177(1):604-11. doi: 10.4049/jimmunol.177.1.604. J Immunol. 2006. PMID: 16785558
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