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Anticancer DNA vaccine based on human telomerase reverse transcriptase generates a strong and specific T cell immune response.
Thalmensi J, Pliquet E, Liard C, Escande M, Bestetti T, Julithe M, Kostrzak A, Pailhes-Jimenez AS, Bourges E, Loustau M, Caumartin J, Lachgar A, Huet T, Wain-Hobson S, Langlade-Demoyen P. Thalmensi J, et al. Among authors: bestetti t. Oncoimmunology. 2015 Nov 5;5(3):e1083670. doi: 10.1080/2162402X.2015.1083670. eCollection 2016 Mar. Oncoimmunology. 2015. PMID: 27141336 Free PMC article.
A DNA telomerase vaccine for canine cancer immunotherapy.
Thalmensi J, Pliquet E, Liard C, Chamel G, Kreuz C, Bestetti T, Escande M, Kostrzak A, Pailhes-Jimenez AS, Bourges E, Julithe M, Bourre L, Keravel O, Clayette P, Huet T, Wain-Hobson S, Langlade-Demoyen P. Thalmensi J, et al. Among authors: bestetti t. Oncotarget. 2019 May 21;10(36):3361-3372. doi: 10.18632/oncotarget.26927. eCollection 2019 May 21. Oncotarget. 2019. PMID: 31164958 Free PMC article.
APOBEC3A intratumoral DNA electroporation in mice.
Kostrzak A, Caval V, Escande M, Pliquet E, Thalmensi J, Bestetti T, Julithe M, Fiette L, Huet T, Wain-Hobson S, Langlade-Demoyen P. Kostrzak A, et al. Among authors: bestetti t. Gene Ther. 2017 Feb;24(2):74-83. doi: 10.1038/gt.2016.77. Epub 2016 Nov 18. Gene Ther. 2017. PMID: 27858943
Strong antigen-specific T-cell immunity induced by a recombinant human TERT measles virus vaccine and amplified by a DNA/viral vector prime boost in IFNAR/CD46 mice.
Pliquet E, Ruffie C, Escande M, Thalmensi J, Najburg V, Combredet C, Bestetti T, Julithe M, Liard C, Huet T, Wain-Hobson S, Tangy F, Langlade-Demoyen P. Pliquet E, et al. Among authors: bestetti t. Cancer Immunol Immunother. 2019 Apr;68(4):533-544. doi: 10.1007/s00262-018-2272-3. Epub 2019 Jan 17. Cancer Immunol Immunother. 2019. PMID: 30656384
Evaluating the Impact of Variable Phosphorothioate Content in Tricyclo-DNA Antisense Oligonucleotides in a Duchenne Muscular Dystrophy Mouse Model.
Echevarría L, Aupy P, Relizani K, Bestetti T, Griffith G, Blandel F, Komisarski M, Haeberli A, Svinartchouk F, Garcia L, Goyenvalle A. Echevarría L, et al. Among authors: bestetti t. Nucleic Acid Ther. 2019 Jun;29(3):148-160. doi: 10.1089/nat.2018.0773. Epub 2019 Apr 22. Nucleic Acid Ther. 2019. PMID: 31009315