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Therapeutic potential of culinary-medicinal mushrooms for the management of neurodegenerative diseases: diversity, metabolite, and mechanism.
Phan CW, David P, Naidu M, Wong KH, Sabaratnam V. Phan CW, et al. Crit Rev Biotechnol. 2015;35(3):355-68. doi: 10.3109/07388551.2014.887649. Crit Rev Biotechnol. 2015. PMID: 24654802 Review.
Therefore, efforts have been devoted to a search for more mushroom species that may improve memory and cognition functions. Such mushrooms include Hericium erinaceus, Ganoderma lucidum, Sarcodon spp., Antrodia camphorata, Pleurotus giganteus, Lignosus rhinocerotis, Grifola …
Therefore, efforts have been devoted to a search for more mushroom species that may improve memory and cognition functions. Such mushrooms i …
Effects of Hericium erinaceus on amyloid beta(25-35) peptide-induced learning and memory deficits in mice.
Mori K, Obara Y, Moriya T, Inatomi S, Nakahata N. Mori K, et al. Biomed Res. 2011 Feb;32(1):67-72. doi: 10.2220/biomedres.32.67. Biomed Res. 2011. PMID: 21383512 Free article.
In the present study, we examined the effects of H. erinaceus on amyloid beta(25-35) peptide-induced learning and memory deficits in mice. Mice were administered 10 g of amyloid beta(25-35) peptide intracerebroventricularly on days 7 and 14, and fed a …
In the present study, we examined the effects of H. erinaceus on amyloid beta(25-35) peptide-induced learning and memory defic …
High molecular weight of polysaccharides from Hericium erinaceus against amyloid beta-induced neurotoxicity.
Cheng JH, Tsai CL, Lien YY, Lee MS, Sheu SC. Cheng JH, et al. BMC Complement Altern Med. 2016 Jun 7;16:170. doi: 10.1186/s12906-016-1154-5. BMC Complement Altern Med. 2016. PMID: 27266872 Free PMC article.
BACKGROUND: Hericium erinaceus (HE) is a well-known mushroom in traditional Chinese food and medicine. ...Here, we purified HE polysaccharides (HEPS), composed of two high molecular weight polysaccharides (1.7 10(5) Da and 1.1 10(5) Da), and evaluated their protective effe …
BACKGROUND: Hericium erinaceus (HE) is a well-known mushroom in traditional Chinese food and medicine. ...Here, we purified HE polysa …
The Cyanthin Diterpenoid and Sesterterpene Constituents of Hericium erinaceus Mycelium Ameliorate Alzheimer's Disease-Related Pathologies in APP/PS1 Transgenic Mice.
Tzeng TT, Chen CC, Chen CC, Tsay HJ, Lee LY, Chen WP, Shen CC, Shiao YJ. Tzeng TT, et al. Int J Mol Sci. 2018 Feb 17;19(2):598. doi: 10.3390/ijms19020598. Int J Mol Sci. 2018. PMID: 29463001 Free PMC article.
A 30 day short-term administration of erinacine A and S were performed to explore the effect of each erinacine on AD-related pathology including amyloid beta production and degradation, plaque formation, plaque growth, glial activation and neurogenesis deterioration …
A 30 day short-term administration of erinacine A and S were performed to explore the effect of each erinacine on AD-related pathology inclu …
Prevention of Early Alzheimer's Disease by Erinacine A-Enriched Hericium erinaceus Mycelia Pilot Double-Blind Placebo-Controlled Study.
Li IC, Chang HH, Lin CH, Chen WP, Lu TH, Lee LY, Chen YW, Chen YP, Chen CC, Lin DP. Li IC, et al. Front Aging Neurosci. 2020 Jun 3;12:155. doi: 10.3389/fnagi.2020.00155. eCollection 2020. Front Aging Neurosci. 2020. PMID: 32581767 Free PMC article.
Moreover, only the placebo group observed significantly lowered biomarkers such as calcium, albumin, apolipoprotein E4, hemoglobin, and brain-derived neurotrophic factor and significantly elevated alpha1-antichymotrypsin and amyloid-beta peptide 1-40 over the study …
Moreover, only the placebo group observed significantly lowered biomarkers such as calcium, albumin, apolipoprotein E4, hemoglobin, and brai …
Erinacine A-enriched Hericium erinaceus mycelium ameliorates Alzheimer's disease-related pathologies in APPswe/PS1dE9 transgenic mice.
Tsai-Teng T, Chin-Chu C, Li-Ya L, Wan-Ping C, Chung-Kuang L, Chien-Chang S, Chi-Ying HF, Chien-Chih C, Shiao YJ. Tsai-Teng T, et al. J Biomed Sci. 2016 Jun 27;23(1):49. doi: 10.1186/s12929-016-0266-z. J Biomed Sci. 2016. PMID: 27350344 Free PMC article.
BACKGROUND: The fruiting body of Hericium erinaceus has been demonstrated to possess anti-dementia activity in mouse model of Alzheimer's disease and people with mild cognitive impairment. However, the therapeutic potential of Hericium erinaceus mycelia on Alzheimer …
BACKGROUND: The fruiting body of Hericium erinaceus has been demonstrated to possess anti-dementia activity in mouse model of Alzheim …
Systemic Screening of Strains of the Lion's Mane Medicinal Mushroom Hericium erinaceus (Higher Basidiomycetes) and Its Protective Effects on Abeta-Triggered Neurotoxicity in PC12 Cells.
Liu Z, Wang Q, Cui J, Wang L, Xiong L, Wang W, Li D, Liu N, Wu Y, Mao C. Liu Z, et al. Int J Med Mushrooms. 2015;17(3):219-29. doi: 10.1615/intjmedmushrooms.v17.i3.20. Int J Med Mushrooms. 2015. PMID: 25954906
Hericium erinaceus possesses multiple medicinal values. To date, however, there have been few studies of the systemic screening of H. erinaceus strains, and the neuroprotective effects of H. erinaceus prepared from homogenized, fresh fruiting bodies are not fully understoo
Hericium erinaceus possesses multiple medicinal values. To date, however, there have been few studies of the systemic screening of H.