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Photochemically obtained N-demethyl derivatives of anthracyclines.
Johdo O, Tone H, Okamoto R, Yoshimoto A, Naganawa H, Sawa T, Takeuchi T. Johdo O, et al. J Antibiot (Tokyo). 1992 Oct;45(10):1653-61. doi: 10.7164/antibiotics.45.1653. J Antibiot (Tokyo). 1992. PMID: 1473993 Free article.
N-Demethyl derivatives obtained from betaclamycin T (7-O-rhodosaminyl-beta-rhodomycinone) were much more cytotoxic while those from the other six antibiotics were rather less active as compared with their parent compounds. ...
N-Demethyl derivatives obtained from betaclamycin T (7-O-rhodosaminyl-beta-rhodomycinone) were much more cytotoxic while those from t …
New anthracycline derivatives from betaclamycin A.
Yoshimoto A, Matsuzawa Y, Ishikura T, Sawa T, Takeuchi T, Umezawa H. Yoshimoto A, et al. J Antibiot (Tokyo). 1984 Aug;37(8):920-2. doi: 10.7164/antibiotics.37.920. J Antibiot (Tokyo). 1984. PMID: 6480506 Free article. No abstract available.
Strong binding of ditrisarubicin B to DNA.
Kunimoto S, Takahashi Y, Uchida T, Takeuchi T, Umezawa H. Kunimoto S, et al. J Antibiot (Tokyo). 1988 May;41(5):655-9. doi: 10.7164/antibiotics.41.655. J Antibiot (Tokyo). 1988. PMID: 3384751 Free article.
The apparent number of binding sites (napp) of ditrisarubicin B per nucleotide of DNA was 0.164, and this value is identical with that of doxorubicin. Betaclamycin A, which has a trisaccharide chain at C-7 but no carbohydrate at C-10 in the aglycone, interacted with DNA to …
The apparent number of binding sites (napp) of ditrisarubicin B per nucleotide of DNA was 0.164, and this value is identical with that of do …