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Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer.
Cunningham D, Humblet Y, Siena S, Khayat D, Bleiberg H, Santoro A, Bets D, Mueser M, Harstrick A, Verslype C, Chau I, Van Cutsem E. Cunningham D, et al. Among authors: bets d. N Engl J Med. 2004 Jul 22;351(4):337-45. doi: 10.1056/NEJMoa033025. N Engl J Med. 2004. PMID: 15269313 Free article. Clinical Trial.
Combined metformin and insulin therapy for patients with type 2 diabetes mellitus.
Ponssen HH, Elte JW, Lehert P, Schouten JP, Bets D. Ponssen HH, et al. Clin Ther. 2000 Jun;22(6):709-18. doi: 10.1016/S0149-2918(00)90005-5. Clin Ther. 2000. PMID: 10929918 Clinical Trial.
Patients received insulin plus either metformin 1,700 mg/d or placebo for 5 months, followed by a 2-month washout period, and were then crossed over to the other treatment arm for 5 months of additional treatment (total treatment period: 12 months). ...
Patients received insulin plus either metformin 1,700 mg/d or placebo for 5 months, followed by a 2-month washout period, and were th …
Long term treatment with metformin in patients with type 2 diabetes and risk of vitamin B-12 deficiency: randomised placebo controlled trial.
de Jager J, Kooy A, Lehert P, Wulffelé MG, van der Kolk J, Bets D, Verburg J, Donker AJ, Stehouwer CD. de Jager J, et al. Among authors: bets d. BMJ. 2010 May 20;340:c2181. doi: 10.1136/bmj.c2181. BMJ. 2010. PMID: 20488910 Free PMC article. Clinical Trial.
Combination of insulin and metformin in the treatment of type 2 diabetes.
Wulffelé MG, Kooy A, Lehert P, Bets D, Ogterop JC, Borger van der Burg B, Donker AJ, Stehouwer CD. Wulffelé MG, et al. Among authors: bets d. Diabetes Care. 2002 Dec;25(12):2133-40. doi: 10.2337/diacare.25.12.2133. Diabetes Care. 2002. PMID: 12453950 Clinical Trial.
Long-term effects of metformin on metabolism and microvascular and macrovascular disease in patients with type 2 diabetes mellitus.
Kooy A, de Jager J, Lehert P, Bets D, Wulffelé MG, Donker AJ, Stehouwer CD. Kooy A, et al. Among authors: bets d. Arch Intern Med. 2009 Mar 23;169(6):616-25. doi: 10.1001/archinternmed.2009.20. Arch Intern Med. 2009. PMID: 19307526 Clinical Trial.
Discontinuation of metformin in type 2 diabetes patients treated with insulin.
Wulffelé MG, Kooy A, Lehert P, Bets D, Oom JA, Borger van der Burg B, Donker AJ, Stehouwer CD. Wulffelé MG, et al. Among authors: bets d. Neth J Med. 2002 Jul;60(6):249-52. Neth J Med. 2002. PMID: 12365468 Free article. Clinical Trial.
Long-term effects of metformin on endothelial function in type 2 diabetes: a randomized controlled trial.
de Jager J, Kooy A, Schalkwijk C, van der Kolk J, Lehert P, Bets D, Wulffelé MG, Donker AJ, Stehouwer CD. de Jager J, et al. Among authors: bets d. J Intern Med. 2014 Jan;275(1):59-70. doi: 10.1111/joim.12128. Epub 2013 Sep 16. J Intern Med. 2014. PMID: 23981104 Free article. Clinical Trial.
Does metformin decrease blood pressure in patients with Type 2 diabetes intensively treated with insulin?
Wulffelé MG, Kooy A, Lehert P, Bets D, Donker AJ, Stehouwer CD. Wulffelé MG, et al. Among authors: bets d. Diabet Med. 2005 Jul;22(7):907-13. doi: 10.1111/j.1464-5491.2005.01554.x. Diabet Med. 2005. PMID: 15975107 Clinical Trial.
Effects of short-term treatment with metformin on serum concentrations of homocysteine, folate and vitamin B12 in type 2 diabetes mellitus: a randomized, placebo-controlled trial.
Wulffelé MG, Kooy A, Lehert P, Bets D, Ogterop JC, Borger van der Burg B, Donker AJ, Stehouwer CD. Wulffelé MG, et al. Among authors: bets d. J Intern Med. 2003 Nov;254(5):455-63. doi: 10.1046/j.1365-2796.2003.01213.x. J Intern Med. 2003. PMID: 14535967 Free article. Clinical Trial.
Effects of short-term treatment with metformin on markers of endothelial function and inflammatory activity in type 2 diabetes mellitus: a randomized, placebo-controlled trial.
De Jager J, Kooy A, Lehert P, Bets D, Wulffelé MG, Teerlink T, Scheffer PG, Schalkwijk CG, Donker AJ, Stehouwer CD. De Jager J, et al. Among authors: bets d. J Intern Med. 2005 Jan;257(1):100-9. doi: 10.1111/j.1365-2796.2004.01420.x. J Intern Med. 2005. PMID: 15606381 Free article. Clinical Trial.
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