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Crystal Structure of an LSD-Bound Human Serotonin Receptor.
Wacker D, Wang S, McCorvy JD, Betz RM, Venkatakrishnan AJ, Levit A, Lansu K, Schools ZL, Che T, Nichols DE, Shoichet BK, Dror RO, Roth BL. Wacker D, et al. Among authors: betz rm. Cell. 2017 Jan 26;168(3):377-389.e12. doi: 10.1016/j.cell.2016.12.033. Cell. 2017. PMID: 28129538 Free PMC article.
Structure-inspired design of β-arrestin-biased ligands for aminergic GPCRs.
McCorvy JD, Butler KV, Kelly B, Rechsteiner K, Karpiak J, Betz RM, Kormos BL, Shoichet BK, Dror RO, Jin J, Roth BL. McCorvy JD, et al. Among authors: betz rm. Nat Chem Biol. 2018 Feb;14(2):126-134. doi: 10.1038/nchembio.2527. Epub 2017 Dec 11. Nat Chem Biol. 2018. PMID: 29227473 Free PMC article.
Structural and Functional Analysis of a β2-Adrenergic Receptor Complex with GRK5.
Komolov KE, Du Y, Duc NM, Betz RM, Rodrigues JPGLM, Leib RD, Patra D, Skiniotis G, Adams CM, Dror RO, Chung KY, Kobilka BK, Benovic JL. Komolov KE, et al. Among authors: betz rm. Cell. 2017 Apr 20;169(3):407-421.e16. doi: 10.1016/j.cell.2017.03.047. Cell. 2017. PMID: 28431242 Free PMC article.
Structural basis for σ1 receptor ligand recognition.
Schmidt HR, Betz RM, Dror RO, Kruse AC. Schmidt HR, et al. Among authors: betz rm. Nat Struct Mol Biol. 2018 Oct;25(10):981-987. doi: 10.1038/s41594-018-0137-2. Epub 2018 Oct 5. Nat Struct Mol Biol. 2018. PMID: 30291362 Free PMC article.
Diverse GPCRs exhibit conserved water networks for stabilization and activation.
Venkatakrishnan AJ, Ma AK, Fonseca R, Latorraca NR, Kelly B, Betz RM, Asawa C, Kobilka BK, Dror RO. Venkatakrishnan AJ, et al. Among authors: betz rm. Proc Natl Acad Sci U S A. 2019 Feb 19;116(8):3288-3293. doi: 10.1073/pnas.1809251116. Epub 2019 Feb 6. Proc Natl Acad Sci U S A. 2019. PMID: 30728297 Free PMC article.
Lipid14: The Amber Lipid Force Field.
Dickson CJ, Madej BD, Skjevik AA, Betz RM, Teigen K, Gould IR, Walker RC. Dickson CJ, et al. Among authors: betz rm. J Chem Theory Comput. 2014 Feb 11;10(2):865-879. doi: 10.1021/ct4010307. Epub 2014 Jan 30. J Chem Theory Comput. 2014. PMID: 24803855 Free PMC article.
11 results