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Immunology, phenotype first. Preface.
Beutler B. Beutler B. Curr Top Microbiol Immunol. 2008;321:v-viii. Curr Top Microbiol Immunol. 2008. PMID: 18727484 No abstract available.
The forward genetic dissection of afferent innate immunity.
Beutler B, Moresco EM. Beutler B, et al. Curr Top Microbiol Immunol. 2008;321:3-26. doi: 10.1007/978-3-540-75203-5_1. Curr Top Microbiol Immunol. 2008. PMID: 18727485 Review.
TLR4 as the mammalian endotoxin sensor.
Beutler B. Beutler B. Curr Top Microbiol Immunol. 2002;270:109-20. doi: 10.1007/978-3-642-59430-4_7. Curr Top Microbiol Immunol. 2002. PMID: 12467247 Review.
Toll-like receptors and their place in immunology. Where does the immune response to infection begin?
Beutler B. Beutler B. Nat Rev Immunol. 2004 Jul;4(7):498. doi: 10.1038/nri1401. Nat Rev Immunol. 2004. PMID: 18293536 No abstract available.
Evolution of the TIR, tolls and TLRs: functional inferences from computational biology.
Beutler B, Rehli M. Beutler B, et al. Curr Top Microbiol Immunol. 2002;270:1-21. doi: 10.1007/978-3-642-59430-4_1. Curr Top Microbiol Immunol. 2002. PMID: 12467241 Review.
Innate immunity and the new forward genetics.
Beutler B. Beutler B. Best Pract Res Clin Haematol. 2016 Dec;29(4):379-387. doi: 10.1016/j.beha.2016.10.018. Epub 2016 Oct 21. Best Pract Res Clin Haematol. 2016. PMID: 27890263 Free PMC article. Review.
Human Adaptive Immunity Rescues an Inborn Error of Innate Immunity.
Israel L, Wang Y, Bulek K, Della Mina E, Zhang Z, Pedergnana V, Chrabieh M, Lemmens NA, Sancho-Shimizu V, Descatoire M, Lasseau T, Israelsson E, Lorenzo L, Yun L, Belkadi A, Moran A, Weisman LE, Vandenesch F, Batteux F, Weller S, Levin M, Herberg J, Abhyankar A, Prando C, Itan Y, van Wamel WJB, Picard C, Abel L, Chaussabel D, Li X, Beutler B, Arkwright PD, Casanova JL, Puel A. Israel L, et al. Among authors: beutler b. Cell. 2017 Feb 23;168(5):789-800.e10. doi: 10.1016/j.cell.2017.01.039. Cell. 2017. PMID: 28235196 Free PMC article.
HCFC2 is needed for IRF1- and IRF2-dependent Tlr3 transcription and for survival during viral infections.
Sun L, Jiang Z, Acosta-Rodriguez VA, Berger M, Du X, Choi JH, Wang J, Wang KW, Kilaru GK, Mohawk JA, Quan J, Scott L, Hildebrand S, Li X, Tang M, Zhan X, Murray AR, La Vine D, Moresco EMY, Takahashi JS, Beutler B. Sun L, et al. Among authors: beutler b. J Exp Med. 2017 Nov 6;214(11):3263-3277. doi: 10.1084/jem.20161630. Epub 2017 Oct 2. J Exp Med. 2017. PMID: 28970238 Free PMC article.
Excessive endosomal TLR signaling causes inflammatory disease in mice with defective SMCR8-WDR41-C9ORF72 complex function.
McAlpine W, Sun L, Wang KW, Liu A, Jain R, San Miguel M, Wang J, Zhang Z, Hayse B, McAlpine SG, Choi JH, Zhong X, Ludwig S, Russell J, Zhan X, Choi M, Li X, Tang M, Moresco EMY, Beutler B, Turer E. McAlpine W, et al. Among authors: beutler b. Proc Natl Acad Sci U S A. 2018 Dec 4;115(49):E11523-E11531. doi: 10.1073/pnas.1814753115. Epub 2018 Nov 15. Proc Natl Acad Sci U S A. 2018. PMID: 30442666 Free PMC article.
Phylogenetic variation and polymorphism at the toll-like receptor 4 locus (TLR4).
Smirnova I, Poltorak A, Chan EK, McBride C, Beutler B. Smirnova I, et al. Among authors: beutler b. Genome Biol. 2000;1(1):RESEARCH002. doi: 10.1186/gb-2000-1-1-research002. Epub 2000 Apr 27. Genome Biol. 2000. PMID: 11104518 Free PMC article.
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