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Gene replacement in parasitic protozoa.
Cruz A, Beverley SM. Cruz A, et al. Nature. 1990 Nov 8;348(6297):171-3. doi: 10.1038/348171a0. Nature. 1990. PMID: 2234081
A molecular docking strategy identifies Eosin B as a non-active site inhibitor of protozoal bifunctional thymidylate synthase-dihydrofolate reductase.
Atreya CE, Johnson EF, Irwin JJ, Dow A, Massimine KM, Coppens I, Stempliuk V, Beverley S, Joiner KA, Shoichet BK, Anderson KS. Atreya CE, et al. J Biol Chem. 2003 Apr 18;278(16):14092-100. doi: 10.1074/jbc.M212690200. Epub 2003 Jan 29. J Biol Chem. 2003. PMID: 12556445
A bifunctional thymidylate synthetase-dihydrofolate reductase in protozoa.
Garrett CE, Coderre JA, Meek TD, Garvey EP, Claman DM, Beverley SM, Santi DV. Garrett CE, et al. Mol Biochem Parasitol. 1984 Apr;11:257-65. doi: 10.1016/0166-6851(84)90070-7. Mol Biochem Parasitol. 1984. PMID: 6749182
Primary structure of the gene encoding the bifunctional dihydrofolate reductase-thymidylate synthase of Leishmania major.
Beverley SM, Ellenberger TE, Cordingley JS. Beverley SM, et al. Proc Natl Acad Sci U S A. 1986 Apr;83(8):2584-8. doi: 10.1073/pnas.83.8.2584. Proc Natl Acad Sci U S A. 1986. PMID: 3458220 Free PMC article.
Parasitology: CRISPR for Cryptosporidium.
Beverley SM. Beverley SM. Nature. 2015 Jul 23;523(7561):413-4. doi: 10.1038/nature14636. Epub 2015 Jul 15. Nature. 2015. PMID: 26176915 Free PMC article.
PTR1-dependent synthesis of tetrahydrobiopterin contributes to oxidant susceptibility in the trypanosomatid protozoan parasite Leishmania major.
Nare B, Garraway LA, Vickers TJ, Beverley SM. Nare B, et al. Curr Genet. 2009 Jun;55(3):287-99. doi: 10.1007/s00294-009-0244-z. Epub 2009 Apr 25. Curr Genet. 2009. PMID: 19396443 Free PMC article.
Folate metabolic pathways in Leishmania.
Vickers TJ, Beverley SM. Vickers TJ, et al. Essays Biochem. 2011;51:63-80. doi: 10.1042/bse0510063. Essays Biochem. 2011. PMID: 22023442 Free PMC article. Review.
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