Bex FJ - Search Results

1

In vitro and in vivo activities of C-terminally truncated PTH peptides reveal a disconnect between cAMP signaling and functional activity.

Murrills RJ, Matteo JJ, Samuel RL, Andrews JL, Bhat BM, Coleburn VE, Kharode YP, Bex FJ. Murrills RJ, et al. Among authors: bex fj. Bone. 2004 Dec;35(6):1263-72. doi: 10.1016/j.bone.2004.08.015. Bone. 2004. PMID: 15589208

2

Identification of a PTH regulated gene selectively induced in vivo during PTH-mediated bone formation.

Robinson JA, Susulic V, Liu YB, Taylor C, Hardenburg J, Gironda V, Zhao W, Kharode Y, McLarney S, Bai Y, Malone DP, Murrills R, Bex F. Robinson JA, et al. J Cell Biochem. 2006 Aug 1;98(5):1203-20. doi: 10.1002/jcb.20822. J Cell Biochem. 2006. PMID: 16514668

3

Parathyroid hormone synergizes with non-cyclic AMP pathways to activate the cyclic AMP response element.

Murrills RJ, Andrews JL, Samuel RL, Coleburn VE, Bhat BM, Bhat RA, Bex FJ, Bodine PV. Murrills RJ, et al. Among authors: bex fj. J Cell Biochem. 2009 Apr 1;106(5):887-95. doi: 10.1002/jcb.22057. J Cell Biochem. 2009. PMID: 19180574

4

High bone mass in mice expressing a mutant LRP5 gene.

Babij P, Zhao W, Small C, Kharode Y, Yaworsky PJ, Bouxsein ML, Reddy PS, Bodine PV, Robinson JA, Bhat B, Marzolf J, Moran RA, Bex F. Babij P, et al. J Bone Miner Res. 2003 Jun;18(6):960-74. doi: 10.1359/jbmr.2003.18.6.960. J Bone Miner Res. 2003. PMID: 12817748 Free article.

5

Bone anabolic effects of parathyroid hormone are blunted by deletion of the Wnt antagonist secreted frizzled-related protein-1.

Bodine PV, Seestaller-Wehr L, Kharode YP, Bex FJ, Komm BS. Bodine PV, et al. Among authors: bex fj. J Cell Physiol. 2007 Feb;210(2):352-7. doi: 10.1002/jcp.20834. J Cell Physiol. 2007. PMID: 17044082

6

Structure-based mutation analysis shows the importance of LRP5 beta-propeller 1 in modulating Dkk1-mediated inhibition of Wnt signaling.

Bhat BM, Allen KM, Liu W, Graham J, Morales A, Anisowicz A, Lam HS, McCauley C, Coleburn V, Cain M, Fortier E, Bhat RA, Bex FJ, Yaworsky PJ. Bhat BM, et al. Among authors: bex fj. Gene. 2007 Apr 15;391(1-2):103-12. doi: 10.1016/j.gene.2006.12.014. Epub 2006 Dec 29. Gene. 2007. PMID: 17276019

7

A cell-based Dkk1 binding assay reveals roles for extracellular domains of LRP5 in Dkk1 interaction and highlights differences between wild-type and the high bone mass mutant LRP5(G171V).

Murrills RJ, Matteo JJ, Bhat BM, Coleburn VE, Allen KM, Chen W, Damagnez V, Bhat RA, Bex FJ, Bodine PV. Murrills RJ, et al. Among authors: bex fj. J Cell Biochem. 2009 Dec 1;108(5):1066-75. doi: 10.1002/jcb.22335. J Cell Biochem. 2009. PMID: 19746449

8

The Wnt antagonist secreted frizzled-related protein-1 is a negative regulator of trabecular bone formation in adult mice.

Bodine PV, Zhao W, Kharode YP, Bex FJ, Lambert AJ, Goad MB, Gaur T, Stein GS, Lian JB, Komm BS. Bodine PV, et al. Among authors: bex fj. Mol Endocrinol. 2004 May;18(5):1222-37. doi: 10.1210/me.2003-0498. Epub 2004 Feb 19. Mol Endocrinol. 2004. PMID: 14976225

9

(1-(4-(Naphthalen-2-yl)pyrimidin-2-yl)piperidin-4-yl)methanamine: a wingless beta-catenin agonist that increases bone formation rate.

Pelletier JC, Lundquist JT 4th, Gilbert AM, Alon N, Bex FJ, Bhat BM, Bursavich MG, Coleburn VE, Felix LA, Green DM, Green P, Hauze DB, Kharode YP, Lam HS, Lockhead SR, Magolda RL, Matteo JJ, Mehlmann JF, Milligan C, Murrills RJ, Pirrello J, Selim S, Sharp MC, Unwalla RJ, Vera MD, Wrobel JE, Yaworsky P, Bodine PV. Pelletier JC, et al. Among authors: bex fj. J Med Chem. 2009 Nov 26;52(22):6962-5. doi: 10.1021/jm9014197. J Med Chem. 2009. PMID: 19856966

10

Hit to lead studies on (hetero)arylpyrimidines--agonists of the canonical Wnt-beta-catenin cellular messaging system.

Gilbert AM, Bursavich MG, Alon N, Bhat BM, Bex FJ, Cain M, Coleburn V, Gironda V, Green P, Hauze DB, Kharode Y, Krishnamurthy G, Kirisits M, Lam HS, Liu YB, Lombardi S, Matteo J, Murrills R, Robinson JA, Selim S, Sharp M, Unwalla R, Varadarajan U, Zhao W, Yaworsky PJ. Gilbert AM, et al. Among authors: bex fj. Bioorg Med Chem Lett. 2010 Jan 1;20(1):366-70. doi: 10.1016/j.bmcl.2009.10.093. Epub 2009 Oct 25. Bioorg Med Chem Lett. 2010. PMID: 19897365

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