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Tunneling Nanotubes Mediate Adaptation of Glioblastoma Cells to Temozolomide and Ionizing Radiation Treatment.
Valdebenito S, Audia A, Bhat KPL, Okafo G, Eugenin EA. Valdebenito S, et al. Among authors: bhat kpl. iScience. 2020 Aug 13;23(9):101450. doi: 10.1016/j.isci.2020.101450. Online ahead of print. iScience. 2020. PMID: 32882515 Free PMC article.
The dystroglycan receptor maintains glioma stem cells in the vascular niche.
Day BW, Lathia JD, Bruce ZC, D'Souza RCJ, Baumgartner U, Ensbey KS, Lim YC, Stringer BW, Akgül S, Offenhäuser C, Li Y, Jamieson PR, Smith FM, Jurd CLR, Robertson T, Inglis PL, Lwin Z, Jeffree RL, Johns TG, Bhat KPL, Rich JN, Campbell KP, Boyd AW. Day BW, et al. Among authors: bhat kpl. Acta Neuropathol. 2019 Dec;138(6):1033-1052. doi: 10.1007/s00401-019-02069-x. Epub 2019 Aug 28. Acta Neuropathol. 2019. PMID: 31463571 Free PMC article.
IL-8 associates with a pro-angiogenic and mesenchymal subtype in glioblastoma.
Conroy S, Kruyt FAE, Wagemakers M, Bhat KPL, den Dunnen WFA. Conroy S, et al. Among authors: bhat kpl. Oncotarget. 2018 Feb 28;9(21):15721-15731. doi: 10.18632/oncotarget.24595. eCollection 2018 Mar 20. Oncotarget. 2018. PMID: 29644004 Free PMC article.
CDK4/6 inhibition is more active against the glioblastoma proneural subtype.
Li M, Xiao A, Floyd D, Olmez I, Lee J, Godlewski J, Bronisz A, Bhat KPL, Sulman EP, Nakano I, Purow B. Li M, et al. Among authors: bhat kpl. Oncotarget. 2017 Jul 21;8(33):55319-55331. doi: 10.18632/oncotarget.19429. eCollection 2017 Aug 15. Oncotarget. 2017. PMID: 28903422 Free PMC article.
The Impact of the Tumor Microenvironment on the Properties of Glioma Stem-Like Cells.
Audia A, Conroy S, Glass R, Bhat KPL. Audia A, et al. Among authors: bhat kpl. Front Oncol. 2017 Jul 10;7:143. doi: 10.3389/fonc.2017.00143. eCollection 2017. Front Oncol. 2017. PMID: 28740831 Free PMC article. Review.
FOXD1-ALDH1A3 Signaling Is a Determinant for the Self-Renewal and Tumorigenicity of Mesenchymal Glioma Stem Cells.
Cheng P, Wang J, Waghmare I, Sartini S, Coviello V, Zhang Z, Kim SH, Mohyeldin A, Pavlyukov MS, Minata M, Valentim CL, Chhipa RR, Bhat KP, Dasgupta B, La Motta C, Kango-Singh M, Nakano I. Cheng P, et al. Cancer Res. 2016 Dec 15;76(24):7219-7230. doi: 10.1158/0008-5472.CAN-15-2860. Epub 2016 Aug 28. Cancer Res. 2016. PMID: 27569208 Free PMC article.
EZH2 protects glioma stem cells from radiation-induced cell death in a MELK/FOXM1-dependent manner.
Kim SH, Joshi K, Ezhilarasan R, Myers TR, Siu J, Gu C, Nakano-Okuno M, Taylor D, Minata M, Sulman EP, Lee J, Bhat KP, Salcini AE, Nakano I. Kim SH, et al. Stem Cell Reports. 2015 Feb 10;4(2):226-38. doi: 10.1016/j.stemcr.2014.12.006. Epub 2015 Jan 15. Stem Cell Reports. 2015. PMID: 25601206 Free PMC article.
EGFR and EGFRvIII in glioblastoma: partners in crime.
Zadeh G, Bhat KP, Aldape K. Zadeh G, et al. Cancer Cell. 2013 Oct 14;24(4):403-4. doi: 10.1016/j.ccr.2013.09.017. Cancer Cell. 2013. PMID: 24135276 Free article.
Mesenchymal differentiation mediated by NF-κB promotes radiation resistance in glioblastoma.
Bhat KPL, Balasubramaniyan V, Vaillant B, Ezhilarasan R, Hummelink K, Hollingsworth F, Wani K, Heathcock L, James JD, Goodman LD, Conroy S, Long L, Lelic N, Wang S, Gumin J, Raj D, Kodama Y, Raghunathan A, Olar A, Joshi K, Pelloski CE, Heimberger A, Kim SH, Cahill DP, Rao G, Den Dunnen WFA, Boddeke HWGM, Phillips HS, Nakano I, Lang FF, Colman H, Sulman EP, Aldape K. Bhat KPL, et al. Cancer Cell. 2013 Sep 9;24(3):331-46. doi: 10.1016/j.ccr.2013.08.001. Epub 2013 Aug 29. Cancer Cell. 2013. PMID: 23993863 Free PMC article.
Not expecting the unexpected: diacylglycerol kinase alpha as a cancer target.
Bhat KP, Aldape K. Bhat KP, et al. Cancer Discov. 2013 Jul;3(7):726-7. doi: 10.1158/2159-8290.CD-13-0244. Cancer Discov. 2013. PMID: 23847350 Free article.
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