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Stochastic variation in the concentration of a repressor activates GAL genetic switch: implications in evolution of regulatory network.
Bhat PJ, Venkatesh KV. Bhat PJ, et al. FEBS Lett. 2005 Jan 31;579(3):597-603. doi: 10.1016/j.febslet.2004.12.038. FEBS Lett. 2005. PMID: 15670814
Quantitative model for Gal4p-mediated expression of the galactose/melibiose regulon in Saccharomyces cerevisiae.
Venkatesh KV, Bhat PJ, Kumar RA, Doshi P. Venkatesh KV, et al. Among authors: bhat pj. Biotechnol Prog. 1999 Jan-Feb;15(1):51-7. doi: 10.1021/bp9801042. Biotechnol Prog. 1999. PMID: 9933513
Expression of human inositol monophosphatase suppresses galactose toxicity in Saccharomyces cerevisiae: possible implications in galactosemia.
Mehta DV, Kabir A, Bhat PJ. Mehta DV, et al. Among authors: bhat pj. Biochim Biophys Acta. 1999 Aug 30;1454(3):217-26. doi: 10.1016/s0925-4439(99)00037-x. Biochim Biophys Acta. 1999. PMID: 10452956
Multiple copies of MRG19 suppress transcription of the GAL1 promoter in a GAL80-dependent manner in Saccharomyces cerevisiae.
Kabir MA, Khanday FA, Mehta DV, Bhat PJ. Kabir MA, et al. Among authors: bhat pj. Mol Gen Genet. 2000 Jan;262(6):1113-22. doi: 10.1007/pl00008654. Mol Gen Genet. 2000. PMID: 10660072
Transcriptional control of the GAL/MEL regulon of yeast Saccharomyces cerevisiae: mechanism of galactose-mediated signal transduction.
Bhat PJ, Murthy TV. Bhat PJ, et al. Mol Microbiol. 2001 Jun;40(5):1059-66. doi: 10.1046/j.1365-2958.2001.02421.x. Mol Microbiol. 2001. PMID: 11401712 Review.
Molecular characterization of MRG19 of Saccharomyces cerevisiae. Implication in the regulation of galactose and nonfermentable carbon source utilization.
Khanday FA, Saha M, Bhat PJ. Khanday FA, et al. Among authors: bhat pj. Eur J Biochem. 2002 Dec;269(23):5840-50. doi: 10.1046/j.1432-1033.2002.03303.x. Eur J Biochem. 2002. PMID: 12444972
Expression of GAL genes in a mutant strain of Saccharomyces cerevisiae lacking GAL80: quantitative model and experimental verification.
Verma M, Bhat PJ, Venkatesh KV. Verma M, et al. Among authors: bhat pj. Biotechnol Appl Biochem. 2004 Feb;39(Pt 1):89-97. doi: 10.1042/BA20030119. Biotechnol Appl Biochem. 2004. PMID: 12927024
Quantitative analysis of GAL genetic switch of Saccharomyces cerevisiae reveals that nucleocytoplasmic shuttling of Gal80p results in a highly sensitive response to galactose.
Verma M, Bhat PJ, Venkatesh KV. Verma M, et al. Among authors: bhat pj. J Biol Chem. 2003 Dec 5;278(49):48764-9. doi: 10.1074/jbc.M303526200. Epub 2003 Sep 25. J Biol Chem. 2003. PMID: 14512430
Autoregulation of regulatory proteins is key for dynamic operation of GAL switch in Saccharomyces cerevisiae.
Ruhela A, Verma M, Edwards JS, Bhat PJ, Bhartiya S, Venkatesh KV. Ruhela A, et al. Among authors: bhat pj. FEBS Lett. 2004 Oct 8;576(1-2):119-26. doi: 10.1016/j.febslet.2004.09.001. FEBS Lett. 2004. PMID: 15474022
A steady-state modeling approach to validate an in vivo mechanism of the GAL regulatory network in Saccharomyces cerevisiae.
Verma M, Bhat PJ, Bhartiya S, Venkatesh KV. Verma M, et al. Among authors: bhat pj. Eur J Biochem. 2004 Oct;271(20):4064-74. doi: 10.1111/j.1432-1033.2004.04344.x. Eur J Biochem. 2004. PMID: 15479235
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