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Interaction between oxidative stress and chemokines: possible pathogenic role in systemic lupus erythematosus and rheumatoid arthritis.
Shah D, Wanchu A, Bhatnagar A. Shah D, et al. Among authors: bhatnagar a. Immunobiology. 2011 Sep;216(9):1010-7. doi: 10.1016/j.imbio.2011.04.001. Epub 2011 Apr 13. Immunobiology. 2011. PMID: 21601309
Imbalance oxidative stress and chemokines are considered as a universal factors involved in the development of various clinical features seen in the patients with SLE and arthritis. ...A significant increase in the level of lipid peroxidation was found in SLE and RA …
Imbalance oxidative stress and chemokines are considered as a universal factors involved in the development of various clinical featu …
Spontaneous and antigen-induced chemokine production in exposed but uninfected partners of HIV type 1-infected individuals in North India.
Suresh P, Wanchu A, Bhatnagar A, Sachdeva RK, Sharma M. Suresh P, et al. Among authors: bhatnagar a. AIDS Res Hum Retroviruses. 2007 Feb;23(2):261-8. doi: 10.1089/aid.2006.0146. AIDS Res Hum Retroviruses. 2007. PMID: 17331032
In this study, the role of beta-chemokines and alpha-chemokine in providing resistance to HIV-1 infection was evaluated in a group of 25 HIV-exposed but uninfected (EU) partners of HIV-1-infected individuals. ...Moreover, a spontaneous production of all the three be …
In this study, the role of beta-chemokines and alpha-chemokine in providing resistance to HIV-1 infection was evaluated in a group of …
Relationship between T lymphocyte subsets and cortisol in systemic lupus erythematosus.
Shah D, Kiran R, Wanchu A, Bhatnagar A. Shah D, et al. Among authors: bhatnagar a. Kathmandu Univ Med J (KUMJ). 2009 Jul-Sep;7(27):213-9. doi: 10.3126/kumj.v7i3.2726. Kathmandu Univ Med J (KUMJ). 2009. PMID: 20071865
BACKGROUND: Systemic Lupus Erythematosus (SLE) is a complex chronic immunological disease characterized by increased B cell activity and altered T cell function. ...A positive correlation was observed between CD8(+) T cells and SLEDAI score. Furthermore, CD8(+) T ce …
BACKGROUND: Systemic Lupus Erythematosus (SLE) is a complex chronic immunological disease characterized by increased B cell activity …
Oxidative stress in systemic lupus erythematosus: relationship to Th1 cytokine and disease activity.
Shah D, Kiran R, Wanchu A, Bhatnagar A. Shah D, et al. Among authors: bhatnagar a. Immunol Lett. 2010 Mar 10;129(1):7-12. doi: 10.1016/j.imlet.2010.01.005. Epub 2010 Jan 25. Immunol Lett. 2010. PMID: 20105444
The estimation of oxidant and anti-oxidant enzymes was done in erythrocyte hemolysate and the levels of IFN-gamma and IL-12 were determined in the culture supernatant of peripheral blood mononuclear cells (PBMC) by a sandwich enzyme-linked immunosorbent assay (ELISA). A
The estimation of oxidant and anti-oxidant enzymes was done in erythrocyte hemolysate and the levels of IFN-gamma and IL-12 were determined …
Association between T lymphocyte sub-sets apoptosis and peripheral blood mononuclear cells oxidative stress in systemic lupus erythematosus.
Shah D, Aggarwal A, Bhatnagar A, Kiran R, Wanchu A. Shah D, et al. Among authors: bhatnagar a. Free Radic Res. 2011 May;45(5):559-67. doi: 10.3109/10715762.2011.555765. Epub 2011 Feb 2. Free Radic Res. 2011. PMID: 21284579
Increased oxidative stress and lymphocyte apoptosis are a hallmark of the autoimmune disease systemic lupus erythematosus (SLE). ...
Increased oxidative stress and lymphocyte apoptosis are a hallmark of the autoimmune disease systemic lupus erythematosus (SLE). ...
Soluble granzyme B and cytotoxic T lymphocyte activity in the pathogenesis of systemic lupus erythematosus.
Shah D, Kiran R, Wanchu A, Bhatnagar A. Shah D, et al. Among authors: bhatnagar a. Cell Immunol. 2011;269(1):16-21. doi: 10.1016/j.cellimm.2011.03.004. Epub 2011 Mar 12. Cell Immunol. 2011. PMID: 21458778
The findings of this study suggest that excessive secretion of soluble granzyme B and enhanced activity of cytotoxic T lymphocyte may play a vital role in the pathogenesis of SLE and organ damage. ...
The findings of this study suggest that excessive secretion of soluble granzyme B and enhanced activity of cytotoxic T lymphocyte may play …
Therapeutic effect of Withania somnifera on pristane-induced model of SLE.
Minhas U, Minz R, Das P, Bhatnagar A. Minhas U, et al. Among authors: bhatnagar a. Inflammopharmacology. 2012 Aug;20(4):195-205. doi: 10.1007/s10787-011-0102-8. Epub 2011 Dec 13. Inflammopharmacology. 2012. PMID: 22160928
Altered redox state and apoptosis in the pathogenesis of systemic lupus erythematosus.
Shah D, Sah S, Wanchu A, Wu MX, Bhatnagar A. Shah D, et al. Among authors: bhatnagar a. Immunobiology. 2013 Apr;218(4):620-7. doi: 10.1016/j.imbio.2012.07.030. Epub 2012 Aug 4. Immunobiology. 2013. PMID: 22940256 Clinical Trial.
Bi(o)communications among peripheral blood fractions: a focus on NK and NKT cell biology in rheumatoid arthritis.
Aggarwal A, Sharma A, Bhatnagar A. Aggarwal A, et al. Among authors: bhatnagar a. Autoimmunity. 2013 Jun;46(4):238-50. doi: 10.3109/08916934.2012.755959. Autoimmunity. 2013. PMID: 23215763
Results indicated a state of profound oxidative stress in the peripheral blood of RA patients where percentage of NK and NKT cell subsets diminished while ROS levels increased. ...
Results indicated a state of profound oxidative stress in the peripheral blood of RA patients where percentage of NK and NKT cell sub …
A study on the association of autoantibodies, chemokine, and its receptor with disease activity in systemic lupus erythematosus in North Indian population.
Bidyalaxmi Devi L, Bhatnagar A, Wanchu A, Sharma A. Bidyalaxmi Devi L, et al. Among authors: bhatnagar a. Rheumatol Int. 2013 Nov;33(11):2819-26. doi: 10.1007/s00296-013-2812-2. Epub 2013 Jul 6. Rheumatol Int. 2013. PMID: 23832290
Systemic lupus erythematosus (SLE) is a chronic and complex autoimmune disease characterized by the production of autoantibodies against a spectrum of nuclear antigens. ...PCR-RFLP performed showed 28C/C and the 403G/G genotypes in both patients and controls, but no …
Systemic lupus erythematosus (SLE) is a chronic and complex autoimmune disease characterized by the production of autoantibodies agai …
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