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Novel aspects of renal organic anion transporters.
Eraly SA, Blantz RC, Bhatnagar V, Nigam SK. Eraly SA, et al. Among authors: bhatnagar v. Curr Opin Nephrol Hypertens. 2003 Sep;12(5):551-8. doi: 10.1097/00041552-200309000-00011. Curr Opin Nephrol Hypertens. 2003. PMID: 12920404 Review.
An Organic Anion Transporter 1 (OAT1)-centered Metabolic Network.
Liu HC, Jamshidi N, Chen Y, Eraly SA, Cho SY, Bhatnagar V, Wu W, Bush KT, Abagyan R, Palsson BO, Nigam SK. Liu HC, et al. Among authors: bhatnagar v. J Biol Chem. 2016 Sep 9;291(37):19474-86. doi: 10.1074/jbc.M116.745216. Epub 2016 Jul 20. J Biol Chem. 2016. PMID: 27440044 Free PMC article.
Conformational changes of the multispecific transporter organic anion transporter 1 (OAT1/SLC22A6) suggests a molecular mechanism for initial stages of drug and metabolite transport.
Tsigelny IF, Kovalskyy D, Kouznetsova VL, Balinskyi O, Sharikov Y, Bhatnagar V, Nigam SK. Tsigelny IF, et al. Among authors: bhatnagar v. Cell Biochem Biophys. 2011 Nov;61(2):251-9. doi: 10.1007/s12013-011-9191-7. Cell Biochem Biophys. 2011. PMID: 21499753
The organic anion transporter (OAT) family: a systems biology perspective.
Nigam SK, Bush KT, Martovetsky G, Ahn SY, Liu HC, Richard E, Bhatnagar V, Wu W. Nigam SK, et al. Among authors: bhatnagar v. Physiol Rev. 2015 Jan;95(1):83-123. doi: 10.1152/physrev.00025.2013. Physiol Rev. 2015. PMID: 25540139 Free PMC article. Review.
The systems biology of uric acid transporters: the role of remote sensing and signaling.
Nigam SK, Bhatnagar V. Nigam SK, et al. Among authors: bhatnagar v. Curr Opin Nephrol Hypertens. 2018 Jul;27(4):305-313. doi: 10.1097/MNH.0000000000000427. Curr Opin Nephrol Hypertens. 2018. PMID: 29847376 Free PMC article. Review.
Handling of Drugs, Metabolites, and Uremic Toxins by Kidney Proximal Tubule Drug Transporters.
Nigam SK, Wu W, Bush KT, Hoenig MP, Blantz RC, Bhatnagar V. Nigam SK, et al. Among authors: bhatnagar v. Clin J Am Soc Nephrol. 2015 Nov 6;10(11):2039-49. doi: 10.2215/CJN.02440314. Epub 2015 Oct 21. Clin J Am Soc Nephrol. 2015. PMID: 26490509 Free PMC article.
Drug and toxicant handling by the OAT organic anion transporters in the kidney and other tissues.
Nigam SK, Bush KT, Bhatnagar V. Nigam SK, et al. Among authors: bhatnagar v. Nat Clin Pract Nephrol. 2007 Aug;3(8):443-8. doi: 10.1038/ncpneph0558. Nat Clin Pract Nephrol. 2007. PMID: 17653123 Review.
Analyses of 5' regulatory region polymorphisms in human SLC22A6 (OAT1) and SLC22A8 (OAT3).
Bhatnagar V, Xu G, Hamilton BA, Truong DM, Eraly SA, Wu W, Nigam SK. Bhatnagar V, et al. J Hum Genet. 2006;51(6):575-580. doi: 10.1007/s10038-006-0398-1. Epub 2006 Apr 29. J Hum Genet. 2006. PMID: 16648942
Analyses of coding region polymorphisms in apical and basolateral human organic anion transporter (OAT) genes [OAT1 (NKT), OAT2, OAT3, OAT4, URAT (RST)].
Xu G, Bhatnagar V, Wen G, Hamilton BA, Eraly SA, Nigam SK. Xu G, et al. Among authors: bhatnagar v. Kidney Int. 2005 Oct;68(4):1491-9. doi: 10.1111/j.1523-1755.2005.00612.x. Kidney Int. 2005. PMID: 16164626
The molecular pharmacology of organic anion transporters: from DNA to FDA?
Eraly SA, Bush KT, Sampogna RV, Bhatnagar V, Nigam SK. Eraly SA, et al. Among authors: bhatnagar v. Mol Pharmacol. 2004 Mar;65(3):479-87. doi: 10.1124/mol.65.3.479. Mol Pharmacol. 2004. PMID: 14978224 Review.
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