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A De Novo Mutation in the Sodium-Activated Potassium Channel KCNT2 Alters Ion Selectivity and Causes Epileptic Encephalopathy.
Gururaj S, Palmer EE, Sheehan GD, Kandula T, Macintosh R, Ying K, Morris P, Tao J, Dias KR, Zhu Y, Dinger ME, Cowley MJ, Kirk EP, Roscioli T, Sachdev R, Duffey ME, Bye A, Bhattacharjee A. Gururaj S, et al. Among authors: bhattacharjee a. Cell Rep. 2017 Oct 24;21(4):926-933. doi: 10.1016/j.celrep.2017.09.088. Cell Rep. 2017. PMID: 29069600 Free PMC article.
For K+ channels, Na+ is the new Ca2+.
Bhattacharjee A, Kaczmarek LK. Bhattacharjee A, et al. Trends Neurosci. 2005 Aug;28(8):422-8. doi: 10.1016/j.tins.2005.06.003. Trends Neurosci. 2005. PMID: 15979166 Review.
Pharmacological activation and inhibition of Slack (Slo2.2) channels.
Yang B, Gribkoff VK, Pan J, Damagnez V, Dworetzky SI, Boissard CG, Bhattacharjee A, Yan Y, Sigworth FJ, Kaczmarek LK. Yang B, et al. Among authors: bhattacharjee a. Neuropharmacology. 2006 Sep;51(4):896-906. doi: 10.1016/j.neuropharm.2006.06.003. Epub 2006 Jul 28. Neuropharmacology. 2006. PMID: 16876206
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