Bi YA - Search Results

1

Permeability comparison between hepatocyte and low efflux MDCKII cell monolayer.

Li R, Bi YA, Lai Y, Sugano K, Steyn SJ, Trapa PE, Di L. Li R, et al. Among authors: bi ya. AAPS J. 2014 Jul;16(4):802-9. doi: 10.1208/s12248-014-9616-5. Epub 2014 May 23. AAPS J. 2014. PMID: 24854896 Free PMC article.

2

Quantitative expression profile of hepatobiliary transporters in sandwich cultured rat and human hepatocytes.

Li N, Bi YA, Duignan DB, Lai Y. Li N, et al. Among authors: bi ya. Mol Pharm. 2009 Jul-Aug;6(4):1180-9. doi: 10.1021/mp900044x. Mol Pharm. 2009. PMID: 19545175

3

Differential modulation of cytochrome P450 activity and the effect of 1-aminobenzotriazole on hepatic transport in sandwich-cultured human hepatocytes.

Kimoto E, Walsky R, Zhang H, Bi YA, Whalen KM, Yang YS, Linder C, Xiao Y, Iseki K, Fenner KS, El-Kattan AF, Lai Y. Kimoto E, et al. Among authors: bi ya. Drug Metab Dispos. 2012 Feb;40(2):407-11. doi: 10.1124/dmd.111.039297. Epub 2011 Oct 26. Drug Metab Dispos. 2012. PMID: 22031626

4

Mechanistic pharmacokinetic modeling for the prediction of transporter-mediated disposition in humans from sandwich culture human hepatocyte data.

Jones HM, Barton HA, Lai Y, Bi YA, Kimoto E, Kempshall S, Tate SC, El-Kattan A, Houston JB, Galetin A, Fenner KS. Jones HM, et al. Among authors: bi ya. Drug Metab Dispos. 2012 May;40(5):1007-17. doi: 10.1124/dmd.111.042994. Epub 2012 Feb 16. Drug Metab Dispos. 2012. PMID: 22344703

5

In vitro evaluation of hepatic transporter-mediated clinical drug-drug interactions: hepatocyte model optimization and retrospective investigation.

Bi YA, Kimoto E, Sevidal S, Jones HM, Barton HA, Kempshall S, Whalen KM, Zhang H, Ji C, Fenner KS, El-Kattan AF, Lai Y. Bi YA, et al. Drug Metab Dispos. 2012 Jun;40(6):1085-92. doi: 10.1124/dmd.111.043489. Epub 2012 Mar 1. Drug Metab Dispos. 2012. PMID: 22381335 Review.

6

A novel relay method for determining low-clearance values.

Di L, Trapa P, Obach RS, Atkinson K, Bi YA, Wolford AC, Tan B, McDonald TS, Lai Y, Tremaine LM. Di L, et al. Among authors: bi ya. Drug Metab Dispos. 2012 Sep;40(9):1860-5. doi: 10.1124/dmd.112.046425. Epub 2012 May 29. Drug Metab Dispos. 2012. PMID: 22645091

7

Mechanistic insights from comparing intrinsic clearance values between human liver microsomes and hepatocytes to guide drug design.

Di L, Keefer C, Scott DO, Strelevitz TJ, Chang G, Bi YA, Lai Y, Duckworth J, Fenner K, Troutman MD, Obach RS. Di L, et al. Among authors: bi ya. Eur J Med Chem. 2012 Nov;57:441-8. doi: 10.1016/j.ejmech.2012.06.043. Epub 2012 Jul 16. Eur J Med Chem. 2012. PMID: 22840492

8

Characterization of organic anion transporting polypeptide (OATP) expression and its functional contribution to the uptake of substrates in human hepatocytes.

Kimoto E, Yoshida K, Balogh LM, Bi YA, Maeda K, El-Kattan A, Sugiyama Y, Lai Y. Kimoto E, et al. Among authors: bi ya. Mol Pharm. 2012 Dec 3;9(12):3535-42. doi: 10.1021/mp300379q. Epub 2012 Nov 2. Mol Pharm. 2012. PMID: 23082789

9

Quantitative prediction of repaglinide-rifampicin complex drug interactions using dynamic and static mechanistic models: delineating differential CYP3A4 induction and OATP1B1 inhibition potential of rifampicin.

Varma MV, Lin J, Bi YA, Rotter CJ, Fahmi OA, Lam JL, El-Kattan AF, Goosen TC, Lai Y. Varma MV, et al. Among authors: bi ya. Drug Metab Dispos. 2013 May;41(5):966-74. doi: 10.1124/dmd.112.050583. Epub 2013 Feb 7. Drug Metab Dispos. 2013. PMID: 23393219

10

Absolute measurement of species differences in sodium taurocholate cotransporting polypeptide (NTCP/Ntcp) and its modulation in cultured hepatocytes.

Qiu X, Bi YA, Balogh LM, Lai Y. Qiu X, et al. Among authors: bi ya. J Pharm Sci. 2013 Sep;102(9):3252-63. doi: 10.1002/jps.23582. Epub 2013 May 8. J Pharm Sci. 2013. PMID: 23657999

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