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Loss of Indian Hedgehog activates multiple aspects of a wound healing response in the mouse intestine.
van Dop WA, Heijmans J, Büller NV, Snoek SA, Rosekrans SL, Wassenberg EA, van den Bergh Weerman MA, Lanske B, Clarke AR, Winton DJ, Wijgerde M, Offerhaus GJ, Hommes DW, Hardwick JC, de Jonge WJ, Biemond I, van den Brink GR. van Dop WA, et al. Among authors: biemond i. Gastroenterology. 2010 Nov;139(5):1665-76, 1676.e1-10. doi: 10.1053/j.gastro.2010.07.045. Epub 2010 Aug 1. Gastroenterology. 2010. PMID: 20682322
Intestinal tumorigenesis is not affected by progesterone signaling in rodent models.
Heijmans J, Muncan V, Jacobs RJ, de Jonge-Muller ES, Graven L, Biemond I, Ederveen AG, Groothuis PG, Mosselman S, Hardwick JC, Hommes DW, van den Brink GR. Heijmans J, et al. Among authors: biemond i. PLoS One. 2011;6(7):e22620. doi: 10.1371/journal.pone.0022620. Epub 2011 Jul 27. PLoS One. 2011. PMID: 21818351 Free PMC article.
Blimp1 regulates the transition of neonatal to adult intestinal epithelium.
Muncan V, Heijmans J, Krasinski SD, Büller NV, Wildenberg ME, Meisner S, Radonjic M, Stapleton KA, Lamers WH, Biemond I, van den Bergh Weerman MA, O'Carroll D, Hardwick JC, Hommes DW, van den Brink GR. Muncan V, et al. Among authors: biemond i. Nat Commun. 2011 Aug 30;2:452. doi: 10.1038/ncomms1463. Nat Commun. 2011. PMID: 21878906 Free PMC article.
Oestrogens promote tumorigenesis in a mouse model for colitis-associated cancer.
Heijmans J, Wielenga MC, Rosekrans SL, van Lidth de Jeude JF, Roelofs J, Groothuis P, Ederveen A, de Jonge-Muller ES, Biemond I, Hardwick JC, D'Haens G, Hommes DW, Muncan V, van den Brink GR. Heijmans J, et al. Among authors: biemond i. Gut. 2014 Feb;63(2):310-6. doi: 10.1136/gutjnl-2012-304216. Epub 2013 Feb 13. Gut. 2014. PMID: 23408349
Loss of SMAD4 alters BMP signaling to promote colorectal cancer cell metastasis via activation of Rho and ROCK.
Voorneveld PW, Kodach LL, Jacobs RJ, Liv N, Zonnevylle AC, Hoogenboom JP, Biemond I, Verspaget HW, Hommes DW, de Rooij K, van Noesel CJ, Morreau H, van Wezel T, Offerhaus GJ, van den Brink GR, Peppelenbosch MP, Ten Dijke P, Hardwick JC. Voorneveld PW, et al. Among authors: biemond i. Gastroenterology. 2014 Jul;147(1):196-208.e13. doi: 10.1053/j.gastro.2014.03.052. Epub 2014 Apr 3. Gastroenterology. 2014. PMID: 24704720
Rage signalling promotes intestinal tumourigenesis.
Heijmans J, Büller NV, Hoff E, Dihal AA, van der Poll T, van Zoelen MA, Bierhaus A, Biemond I, Hardwick JC, Hommes DW, Muncan V, van den Brink GR. Heijmans J, et al. Among authors: biemond i. Oncogene. 2013 Feb 28;32(9):1202-6. doi: 10.1038/onc.2012.119. Epub 2012 Apr 2. Oncogene. 2013. PMID: 22469986
133 results