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CD28 engagement promotes actin polymerization through the activation of the small Rho GTPase Cdc42 in human T cells.
Salazar-Fontana LI, Barr V, Samelson LE, Bierer BE. Salazar-Fontana LI, et al. J Immunol. 2003 Sep 1;171(5):2225-32. doi: 10.4049/jimmunol.171.5.2225. J Immunol. 2003. PMID: 12928366
Such structures were specific for engagement of CD28 on mAb-coated surfaces because they could not be observed in surfaces coated with either poly(L-lysine) or anti-CD3 mAb. ...
Such structures were specific for engagement of CD28 on mAb-coated surfaces because they could not be observed in surfaces coated wit …
Ex vivo rapamycin generates donor Th2 cells that potently inhibit graft-versus-host disease and graft-versus-tumor effects via an IL-4-dependent mechanism.
Foley JE, Jung U, Miera A, Borenstein T, Mariotti J, Eckhaus M, Bierer BE, Fowler DH. Foley JE, et al. J Immunol. 2005 Nov 1;175(9):5732-43. doi: 10.4049/jimmunol.175.9.5732. J Immunol. 2005. PMID: 16237064
Intracellular mediators regulate CD2 lateral diffusion and cytoplasmic Ca2+ mobilization upon CD2-mediated T cell activation.
Liu SJ, Hahn WC, Bierer BE, Golan DE. Liu SJ, et al. Biophys J. 1995 Feb;68(2):459-70. doi: 10.1016/S0006-3495(95)80207-9. Biophys J. 1995. PMID: 7696499 Free PMC article.
In separate experiments, activation-associated cytoplasmic Ca2+ mobilization was found to require microfilament integrity and to be negatively regulated by cAMP. ...
In separate experiments, activation-associated cytoplasmic Ca2+ mobilization was found to require microfilament integrity and to be n …
Gene immunotherapy in murine acute myeloid leukemia: granulocyte-macrophage colony-stimulating factor tumor cell vaccines elicit more potent antitumor immunity compared with B7 family and other cytokine vaccines.
Dunussi-Joannopoulos K, Dranoff G, Weinstein HJ, Ferrara JL, Bierer BE, Croop JM. Dunussi-Joannopoulos K, et al. Blood. 1998 Jan 1;91(1):222-30. Blood. 1998. PMID: 9414288
We have previously shown that leukemic mice can be cured with CD80 transfected leukemic cells (B7. 1-AML vaccine) administered early in the course of the disease and that the failure B7.1-AML vaccines administered late cannot be attributed to immunosuppression induc …
We have previously shown that leukemic mice can be cured with CD80 transfected leukemic cells (B7. 1-AML vaccine) administered early …
Adhesion receptors in lymphocyte activation.
Collins TL, Kassner PD, Bierer BE, Burakoff SJ. Collins TL, et al. Curr Opin Immunol. 1994 Jun;6(3):385-93. doi: 10.1016/0952-7915(94)90117-1. Curr Opin Immunol. 1994. PMID: 7917106 Review.
Analysis of CD4 and CD2 receptor function.
Goldman SJ, Bierer BE, Burakoff SJ. Goldman SJ, et al. Princess Takamatsu Symp. 1988;19:149-60. Princess Takamatsu Symp. 1988. PMID: 2908352
Different monoclonal antibodies (mAbs) against CD4 and CD2 were used to define regions of these molecules that may be important for ligand binding and function. Using anti-CD4 mAbs in combination with anti-CD3 mAb, and measuring IL-2 production and mobilization of cellular …
Different monoclonal antibodies (mAbs) against CD4 and CD2 were used to define regions of these molecules that may be important for l …
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