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Diagnostic value and clinical laboratory associations of antibodies against recombinant ribosomal P0, P1 and P2 proteins and their native heterocomplex in a Caucasian cohort with systemic lupus erythematosus.
Barkhudarova F, Dähnrich C, Rosemann A, Schneider U, Stöcker W, Burmester GR, Egerer K, Schlumberger W, Hiepe F, Biesen R. Barkhudarova F, et al. Among authors: biesen r. Arthritis Res Ther. 2011 Feb 10;13(1):R20. doi: 10.1186/ar3244. Arthritis Res Ther. 2011. PMID: 21310064 Free PMC article.
Nuclear antigen-reactive CD4+ T cells expand in active systemic lupus erythematosus, produce effector cytokines, and invade the kidneys.
Abdirama D, Tesch S, Grießbach AS, von Spee-Mayer C, Humrich JY, Stervbo U, Babel N, Meisel C, Alexander T, Biesen R, Bacher P, Scheffold A, Eckardt KU, Hiepe F, Radbruch A, Burmester GR, Riemekasten G, Enghard P. Abdirama D, et al. Among authors: biesen r. Kidney Int. 2021 Jan;99(1):238-246. doi: 10.1016/j.kint.2020.05.051. Epub 2020 Jun 24. Kidney Int. 2021. PMID: 32592813
Targeting CD38 with Daratumumab in Refractory Systemic Lupus Erythematosus.
Ostendorf L, Burns M, Durek P, Heinz GA, Heinrich F, Garantziotis P, Enghard P, Richter U, Biesen R, Schneider U, Knebel F, Burmester G, Radbruch A, Mei HE, Mashreghi MF, Hiepe F, Alexander T. Ostendorf L, et al. Among authors: biesen r. N Engl J Med. 2020 Sep 17;383(12):1149-1155. doi: 10.1056/NEJMoa2023325. N Engl J Med. 2020. PMID: 32937047
IFNα and its response proteins, IP-10 and SIGLEC-1, are biomarkers of disease activity in systemic lupus erythematosus.
Rose T, Grützkau A, Hirseland H, Huscher D, Dähnrich C, Dzionek A, Ozimkowski T, Schlumberger W, Enghard P, Radbruch A, Riemekasten G, Burmester GR, Hiepe F, Biesen R. Rose T, et al. Among authors: biesen r. Ann Rheum Dis. 2013 Oct;72(10):1639-45. doi: 10.1136/annrheumdis-2012-201586. Epub 2012 Oct 31. Ann Rheum Dis. 2013. PMID: 23117242
Urinary CD4 T cells identify SLE patients with proliferative lupus nephritis and can be used to monitor treatment response.
Enghard P, Rieder C, Kopetschke K, Klocke JR, Undeutsch R, Biesen R, Dragun D, Gollasch M, Schneider U, Aupperle K, Humrich JY, Hiepe F, Backhaus M, Radbruch AH, Burmester GR, Riemekasten G. Enghard P, et al. Among authors: biesen r. Ann Rheum Dis. 2014 Jan;73(1):277-83. doi: 10.1136/annrheumdis-2012-202784. Epub 2013 Mar 8. Ann Rheum Dis. 2014. PMID: 23475982 Clinical Trial.
[DNA microarrays].
Biesen R, Häupl T. Biesen R, et al. Z Rheumatol. 2011 Nov;70(9):803-6, 808. doi: 10.1007/s00393-011-0869-4. Z Rheumatol. 2011. PMID: 21956826 German.
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