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Year Number of Results
2001 1
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2010 9
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2012 17
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363 results

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Page 1
Bifidobacterium breve CCFM1025 attenuates major depression disorder via regulating gut microbiome and tryptophan metabolism: A randomized clinical trial.
Tian P, Chen Y, Zhu H, Wang L, Qian X, Zou R, Zhao J, Zhang H, Qian L, Wang Q, Wang G, Chen W. Tian P, et al. Brain Behav Immun. 2022 Feb;100:233-241. doi: 10.1016/j.bbi.2021.11.023. Epub 2021 Dec 4. Brain Behav Immun. 2022. PMID: 34875345 Clinical Trial.
OBJECTIVE: Psychobiotics, as a novel class of probiotics mainly acting on the gut-brain axis, have shown promising prospects in treating psychiatric disorders. Bifidobacterium breve CCFM1025 was validated to have an antidepressant-like effect in mice. ...CONCLUSION: …
OBJECTIVE: Psychobiotics, as a novel class of probiotics mainly acting on the gut-brain axis, have shown promising prospects in treating psy …
Effect of Probiotic Bifidobacterium breve in Improving Cognitive Function and Preventing Brain Atrophy in Older Patients with Suspected Mild Cognitive Impairment: Results of a 24-Week Randomized, Double-Blind, Placebo-Controlled Trial.
Asaoka D, Xiao J, Takeda T, Yanagisawa N, Yamazaki T, Matsubara Y, Sugiyama H, Endo N, Higa M, Kasanuki K, Ichimiya Y, Koido S, Ohno K, Bernier F, Katsumata N, Nagahara A, Arai H, Ohkusa T, Sato N. Asaoka D, et al. J Alzheimers Dis. 2022;88(1):75-95. doi: 10.3233/JAD-220148. J Alzheimers Dis. 2022. PMID: 35570493 Free PMC article. Clinical Trial.
OBJECTIVE: We investigated the effect of the probiotic strain Bifidobacterium breve MCC1274 (A1) in enhancing cognition and preventing brain atrophy of older patients with mild cognitive impairment (MCI). ...Probiotics consumption for 24 weeks suppressed brain atrop …
OBJECTIVE: We investigated the effect of the probiotic strain Bifidobacterium breve MCC1274 (A1) in enhancing cognition and pr …
Bifidobacterium breve-derived indole-3-lactic acid ameliorates colitis-associated tumorigenesis by directing the differentiation of immature colonic macrophages.
Li Y, Li Q, Yuan R, Wang Y, Guo C, Wang L. Li Y, et al. Theranostics. 2024 Apr 22;14(7):2719-2735. doi: 10.7150/thno.92350. eCollection 2024. Theranostics. 2024. PMID: 38773969 Free PMC article.
Aim: To elucidate dynamics and functions in colonic macrophage subsets, and their regulation by Bifidobacterium breve (B. breve) and its associated metabolites in the initiation of colitis-associated colorectal cancer (CAC). ...On the contrary, the ablation o …
Aim: To elucidate dynamics and functions in colonic macrophage subsets, and their regulation by Bifidobacterium breve (B. b …
Bifidobacteria with indole-3-lactic acid-producing capacity exhibit psychobiotic potential via reducing neuroinflammation.
Qian X, Li Q, Zhu H, Chen Y, Lin G, Zhang H, Chen W, Wang G, Tian P. Qian X, et al. Cell Rep Med. 2024 Nov 19;5(11):101798. doi: 10.1016/j.xcrm.2024.101798. Epub 2024 Oct 28. Cell Rep Med. 2024. PMID: 39471819 Free PMC article.
This study reveals a significant reduction in hippocampal indole-3-lactic acid (ILA) levels in depressed mice, which is ameliorated by the psychobiotic Bifidobacterium breve. In both human subjects and mice, the ILA increase in the circulatory system results from bi …
This study reveals a significant reduction in hippocampal indole-3-lactic acid (ILA) levels in depressed mice, which is ameliorated by the p …
Genome-scale resources in the infant gut symbiont Bifidobacterium breve reveal genetic determinants of colonization and host-microbe interactions.
Shiver AL, Sun J, Culver R, Violette A, Wynter C, Nieckarz M, Mattiello SP, Sekhon PK, Bottacini F, Friess L, Carlson HK, Wong DPGH, Higginbottom S, Weglarz M, Wang W, Knapp BD, Guiberson E, Sanchez J, Huang PH, Garcia PA, Buie CR, Good BH, DeFelice B, Cava F, Scaria J, Sonnenburg JL, Van Sinderen D, Deutschbauer AM, Huang KC. Shiver AL, et al. Cell. 2025 Apr 3;188(7):2003-2021.e19. doi: 10.1016/j.cell.2025.02.010. Epub 2025 Mar 10. Cell. 2025. PMID: 40068681 Free article.
Bifidobacteria represent a dominant constituent of human gut microbiomes during infancy, influencing nutrition, immune development, and resistance to infection. ...To address these major knowledge gaps, we used a large-scale genetic approach to create a mutant fitness comp …
Bifidobacteria represent a dominant constituent of human gut microbiomes during infancy, influencing nutrition, immune development, a …
Gut Microbiome and Metabolome Alterations in Overweight or Obese Adult Population after Weight-Loss Bifidobacterium breve BBr60 Intervention: A Randomized Controlled Trial.
Bai Z, Wu Y, Gao D, Dong Y, Pan Y, Gu S. Bai Z, et al. Int J Mol Sci. 2024 Oct 10;25(20):10871. doi: 10.3390/ijms252010871. Int J Mol Sci. 2024. PMID: 39456659 Free PMC article. Clinical Trial.
Probiotics, known for regulating gut microbiota, may aid those with overweight or obesity, but their mechanisms require more research. This study involved 75 overweight or obese young adults, randomly assigned to either a Bifidobacterium breve BBr60 (BBr60) g …
Probiotics, known for regulating gut microbiota, may aid those with overweight or obesity, but their mechanisms require more research …
Cholecystectomy-related gut microbiota dysbiosis exacerbates colorectal tumorigenesis.
Tang B, Li S, Li X, He J, Zhou A, Wu L, Xiao X, Wang S, Jiang H, Jian J, Hou Z, Ge Y, Lei Y, Zhou J, Tu D, Lu C, Yang M, Yang S. Tang B, et al. Nat Commun. 2025 Aug 16;16(1):7638. doi: 10.1038/s41467-025-62956-8. Nat Commun. 2025. PMID: 40819131 Free PMC article.
Metagenomic sequencing and targeted metabolomics show that cholecystectomy leads to a decrease of Bifidobacterium breve (B. breve) and an increase of Ruminococcus gnavus (R. gnavus), along with increased levels of glycoursodeoxycholic acid (GUDCA) in human an …
Metagenomic sequencing and targeted metabolomics show that cholecystectomy leads to a decrease of Bifidobacterium breve (B. …
Effects of Bifidobacterium breve 207-1 on regulating lifestyle behaviors and mental wellness in healthy adults based on the microbiome-gut-brain axis: a randomized, double-blind, placebo-controlled trial.
Li J, Li Y, Zhao J, Li L, Wang Y, Chen F, Li Y, Cheng R, He F, Ze X, Shen X. Li J, et al. Eur J Nutr. 2024 Oct;63(7):2567-2585. doi: 10.1007/s00394-024-03447-2. Epub 2024 Jun 13. Eur J Nutr. 2024. PMID: 38869657 Clinical Trial.
PURPOSE: Our study aimed to explore the efficacy of Bifidobacterium breve 207-1 on specific neurotransmitters and hormones and the ability to regulate lifestyle behaviors in healthy adults. ...There was a slight decrease in alpha-diversity in the HD group. CONCLUSIO …
PURPOSE: Our study aimed to explore the efficacy of Bifidobacterium breve 207-1 on specific neurotransmitters and hormones and …
Temporal development of the gut microbiome in early childhood from the TEDDY study.
Stewart CJ, Ajami NJ, O'Brien JL, Hutchinson DS, Smith DP, Wong MC, Ross MC, Lloyd RE, Doddapaneni H, Metcalf GA, Muzny D, Gibbs RA, Vatanen T, Huttenhower C, Xavier RJ, Rewers M, Hagopian W, Toppari J, Ziegler AG, She JX, Akolkar B, Lernmark A, Hyoty H, Vehik K, Krischer JP, Petrosino JF. Stewart CJ, et al. Nature. 2018 Oct;562(7728):583-588. doi: 10.1038/s41586-018-0617-x. Epub 2018 Oct 24. Nature. 2018. PMID: 30356187 Free PMC article.
We show that the developing gut microbiome undergoes three distinct phases of microbiome progression: a developmental phase (months 3-14), a transitional phase (months 15-30), and a stable phase (months 31-46). Receipt of breast milk, either exclusive or partial, wa …
We show that the developing gut microbiome undergoes three distinct phases of microbiome progression: a developmental phase (m …
Genomic Characterization and Safety Assessment of Bifidobacterium breve BS2-PB3 as Functional Food.
Marbun KT, Sugata M, Purnomo JS, Dikson, Mudana SO, Jan TT, Jo J. Marbun KT, et al. J Microbiol Biotechnol. 2024 Apr 28;34(4):871-879. doi: 10.4014/jmb.2311.11031. Epub 2024 Jan 25. J Microbiol Biotechnol. 2024. PMID: 38494884 Free PMC article.
Our group had isolated Bifidobacterium breve strain BS2-PB3 from human breast milk. In this study, we sequenced the whole genome of B. breve BS2-PB3, and with a focus on its safety profile, various probiotic characteristics (presence of antibiotic resistance …
Our group had isolated Bifidobacterium breve strain BS2-PB3 from human breast milk. In this study, we sequenced the whole geno …
363 results