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The endocannabinoid system and its therapeutic exploitation.
Di Marzo V, Bifulco M, De Petrocellis L. Di Marzo V, et al. Among authors: bifulco m. Nat Rev Drug Discov. 2004 Sep;3(9):771-84. doi: 10.1038/nrd1495. Nat Rev Drug Discov. 2004. PMID: 15340387 Review.
1,2-Dihydro-2-oxopyridine-3-carboxamides: the C-5 substituent is responsible for functionality switch at CB2 cannabinoid receptor.
Lucchesi V, Parkkari T, Savinainen JR, Malfitano AM, AllarĂ  M, Bertini S, Castelli F, Del Carlo S, Laezza C, Ligresti A, Saccomanni G, Bifulco M, Di Marzo V, Macchia M, Manera C. Lucchesi V, et al. Among authors: bifulco m. Eur J Med Chem. 2014 Mar 3;74:524-32. doi: 10.1016/j.ejmech.2013.10.070. Epub 2014 Jan 21. Eur J Med Chem. 2014. PMID: 24518874
A new strategy to block tumor growth by inhibiting endocannabinoid inactivation.
Bifulco M, Laezza C, Valenti M, Ligresti A, Portella G, DI Marzo V. Bifulco M, et al. FASEB J. 2004 Oct;18(13):1606-8. doi: 10.1096/fj.04-1754fje. Epub 2004 Aug 2. FASEB J. 2004. PMID: 15289448
Possible endocannabinoid control of colorectal cancer growth.
Ligresti A, Bisogno T, Matias I, De Petrocellis L, Cascio MG, Cosenza V, D'argenio G, Scaglione G, Bifulco M, Sorrentini I, Di Marzo V. Ligresti A, et al. Among authors: bifulco m. Gastroenterology. 2003 Sep;125(3):677-87. doi: 10.1016/s0016-5085(03)00881-3. Gastroenterology. 2003. PMID: 12949714
Effect on cancer cell proliferation of palmitoylethanolamide, a fatty acid amide interacting with both the cannabinoid and vanilloid signalling systems.
De Petrocellis L, Bisogno T, Ligresti A, Bifulco M, Melck D, Di Marzo V. De Petrocellis L, et al. Among authors: bifulco m. Fundam Clin Pharmacol. 2002 Aug;16(4):297-302. doi: 10.1046/j.1472-8206.2002.00094.x. Fundam Clin Pharmacol. 2002. PMID: 12570018
End of the line for cannabinoid receptor 1 as an anti-obesity target? An opinion.
Bifulco M, Pisanti S. Bifulco M, et al. Nat Rev Drug Discov. 2009 Jul;8(7):594. doi: 10.1038/nrd2775-c1. Nat Rev Drug Discov. 2009. PMID: 19568284 No abstract available.
Interaction of endocannabinoid system and steroid hormones in the control of colon cancer cell growth.
Proto MC, Gazzerro P, Di Croce L, Santoro A, Malfitano AM, Pisanti S, Laezza C, Bifulco M. Proto MC, et al. Among authors: bifulco m. J Cell Physiol. 2012 Jan;227(1):250-8. doi: 10.1002/jcp.22727. J Cell Physiol. 2012. PMID: 21412772
Update on the endocannabinoid system as an anticancer target.
Malfitano AM, Ciaglia E, Gangemi G, Gazzerro P, Laezza C, Bifulco M. Malfitano AM, et al. Among authors: bifulco m. Expert Opin Ther Targets. 2011 Mar;15(3):297-308. doi: 10.1517/14728222.2011.553606. Epub 2011 Jan 19. Expert Opin Ther Targets. 2011. PMID: 21244344 Review.
Anandamide inhibits adhesion and migration of breast cancer cells.
Grimaldi C, Pisanti S, Laezza C, Malfitano AM, Santoro A, Vitale M, Caruso MG, Notarnicola M, Iacuzzo I, Portella G, Di Marzo V, Bifulco M. Grimaldi C, et al. Among authors: bifulco m. Exp Cell Res. 2006 Feb 15;312(4):363-73. doi: 10.1016/j.yexcr.2005.10.024. Epub 2005 Dec 15. Exp Cell Res. 2006. PMID: 16343481
Palmitoylethanolamide inhibits the expression of fatty acid amide hydrolase and enhances the anti-proliferative effect of anandamide in human breast cancer cells.
Di Marzo V, Melck D, Orlando P, Bisogno T, Zagoory O, Bifulco M, Vogel Z, De Petrocellis L. Di Marzo V, et al. Among authors: bifulco m. Biochem J. 2001 Aug 15;358(Pt 1):249-55. doi: 10.1042/0264-6021:3580249. Biochem J. 2001. PMID: 11485574 Free PMC article.
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