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Nuclear IKK activity leads to dysregulated notch-dependent gene expression in colorectal cancer.
Fernández-Majada V, Aguilera C, Villanueva A, Vilardell F, Robert-Moreno A, Aytés A, Real FX, Capella G, Mayo MW, Espinosa L, Bigas A. Fernández-Majada V, et al. Among authors: bigas a. Proc Natl Acad Sci U S A. 2007 Jan 2;104(1):276-81. doi: 10.1073/pnas.0606476104. Epub 2006 Dec 26. Proc Natl Acad Sci U S A. 2007. PMID: 17190815 Free PMC article.
Jagged1 is the pathological link between Wnt and Notch pathways in colorectal cancer.
Rodilla V, Villanueva A, Obrador-Hevia A, Robert-Moreno A, Fernández-Majada V, Grilli A, López-Bigas N, Bellora N, Albà MM, Torres F, Duñach M, Sanjuan X, Gonzalez S, Gridley T, Capella G, Bigas A, Espinosa L. Rodilla V, et al. Among authors: bigas a. Proc Natl Acad Sci U S A. 2009 Apr 14;106(15):6315-20. doi: 10.1073/pnas.0813221106. Epub 2009 Mar 26. Proc Natl Acad Sci U S A. 2009. PMID: 19325125 Free PMC article.
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