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The on-off story of protein palmitoylation.
Bijlmakers MJ, Marsh M. Bijlmakers MJ, et al. Trends Cell Biol. 2003 Jan;13(1):32-42. doi: 10.1016/s0962-8924(02)00008-9. Trends Cell Biol. 2003. PMID: 12480338 Review.
Protein acylation and localization in T cell signaling (Review).
Bijlmakers MJ. Bijlmakers MJ. Mol Membr Biol. 2009 Jan;26(1):93-103. doi: 10.1080/09687680802650481. Epub 2008 Dec 29. Mol Membr Biol. 2009. PMID: 19115146 Review.
CD8 Raft localization is induced by its assembly into CD8alpha beta heterodimers, Not CD8alpha alpha homodimers.
Pang DJ, Hayday AC, Bijlmakers MJ. Pang DJ, et al. Among authors: bijlmakers mj. J Biol Chem. 2007 May 4;282(18):13884-94. doi: 10.1074/jbc.M701027200. Epub 2007 Mar 6. J Biol Chem. 2007. PMID: 17341584
Regulation of the Src family kinase Lck by Hsp90 and ubiquitination.
Giannini A, Bijlmakers MJ. Giannini A, et al. Among authors: bijlmakers mj. Mol Cell Biol. 2004 Jul;24(13):5667-76. doi: 10.1128/MCB.24.13.5667-5676.2004. Mol Cell Biol. 2004. PMID: 15199125 Free PMC article.
Bijlmakers and M. Marsh, Mol. Biol. Cell. 11:1585-1595, 2000). Here we establish that following TCR stimulation, endogenous activated Lck in T cells is also degraded in the presence of the Hsp90 inhibitor geldanamycin. ...
Bijlmakers and M. Marsh, Mol. Biol. Cell. 11:1585-1595, 2000). Here we establish that following TCR stimulation, endogenous activated
Hsp90 is essential for the synthesis and subsequent membrane association, but not the maintenance, of the Src-kinase p56(lck).
Bijlmakers MJ, Marsh M. Bijlmakers MJ, et al. Mol Biol Cell. 2000 May;11(5):1585-95. doi: 10.1091/mbc.11.5.1585. Mol Biol Cell. 2000. PMID: 10793137 Free PMC article.
Trafficking of an acylated cytosolic protein: newly synthesized p56(lck) travels to the plasma membrane via the exocytic pathway.
Bijlmakers MJ, Marsh M. Bijlmakers MJ, et al. J Cell Biol. 1999 May 3;145(3):457-68. doi: 10.1083/jcb.145.3.457. J Cell Biol. 1999. PMID: 10225948 Free PMC article.
Intrinsic signals in the unique domain target p56(lck) to the plasma membrane independently of CD4.
Bijlmakers MJ, Isobe-Nakamura M, Ruddock LJ, Marsh M. Bijlmakers MJ, et al. J Cell Biol. 1997 Jun 2;137(5):1029-40. doi: 10.1083/jcb.137.5.1029. J Cell Biol. 1997. PMID: 9166404 Free PMC article.
T-cell regulator RNF125/TRAC-1 belongs to a novel family of ubiquitin ligases with zinc fingers and a ubiquitin-binding domain.
Giannini AL, Gao Y, Bijlmakers MJ. Giannini AL, et al. Among authors: bijlmakers mj. Biochem J. 2008 Feb 15;410(1):101-11. doi: 10.1042/BJ20070995. Biochem J. 2008. PMID: 17990982 Free PMC article.
Functional analysis of the RNF114 psoriasis susceptibility gene implicates innate immune responses to double-stranded RNA in disease pathogenesis.
Bijlmakers MJ, Kanneganti SK, Barker JN, Trembath RC, Capon F. Bijlmakers MJ, et al. Hum Mol Genet. 2011 Aug 15;20(16):3129-37. doi: 10.1093/hmg/ddr215. Epub 2011 May 13. Hum Mol Genet. 2011. PMID: 21571784 Free PMC article.
Lack of p56lck expression correlates with CD4 endocytosis in primary lymphoid and myeloid cells.
Pelchen-Matthews A, da Silva RP, Bijlmakers MJ, Signoret N, Gordon S, Marsh M. Pelchen-Matthews A, et al. Among authors: bijlmakers mj. Eur J Immunol. 1998 Nov;28(11):3639-47. doi: 10.1002/(SICI)1521-4141(199811)28:11<3639::AID-IMMU3639>3.0.CO;2-Q. Eur J Immunol. 1998. PMID: 9842906
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