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Sphingolipids and hepatic steatosis.
Bikman BT, Summers SA. Bikman BT, et al. Adv Exp Med Biol. 2011;721:87-97. doi: 10.1007/978-1-4614-0650-1_6. Adv Exp Med Biol. 2011. PMID: 21910084 Review.
Lipid-induced insulin resistance mediated by the proinflammatory receptor TLR4 requires saturated fatty acid-induced ceramide biosynthesis in mice.
Holland WL, Bikman BT, Wang LP, Yuguang G, Sargent KM, Bulchand S, Knotts TA, Shui G, Clegg DJ, Wenk MR, Pagliassotti MJ, Scherer PE, Summers SA. Holland WL, et al. Among authors: bikman bt. J Clin Invest. 2011 May;121(5):1858-70. doi: 10.1172/JCI43378. Epub 2011 Apr 1. J Clin Invest. 2011. PMID: 21490391 Free PMC article.
Ceramides mediate cigarette smoke-induced metabolic disruption in mice.
Thatcher MO, Tippetts TS, Nelson MB, Swensen AC, Winden DR, Hansen ME, Anderson MC, Johnson IE, Porter JP, Reynolds PR, Bikman BT. Thatcher MO, et al. Among authors: bikman bt. Am J Physiol Endocrinol Metab. 2014 Nov 15;307(10):E919-27. doi: 10.1152/ajpendo.00258.2014. Epub 2014 Sep 30. Am J Physiol Endocrinol Metab. 2014. PMID: 25269485
Receptor-mediated activation of ceramidase activity initiates the pleiotropic actions of adiponectin.
Holland WL, Miller RA, Wang ZV, Sun K, Barth BM, Bui HH, Davis KE, Bikman BT, Halberg N, Rutkowski JM, Wade MR, Tenorio VM, Kuo MS, Brozinick JT, Zhang BB, Birnbaum MJ, Summers SA, Scherer PE. Holland WL, et al. Among authors: bikman bt. Nat Med. 2011 Jan;17(1):55-63. doi: 10.1038/nm.2277. Epub 2010 Dec 26. Nat Med. 2011. PMID: 21186369 Free PMC article.
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