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The de novo synthesis of numerous proteins is decreased during vitamin D3 deficiency and is gradually restored by 1, 25-dihydroxyvitamin D3 repletion in the islets of langerhans of rats.
Bourlon PM, Faure-Dussert A, Billaudel B. Bourlon PM, et al. Among authors: billaudel b. J Endocrinol. 1999 Jul;162(1):101-9. doi: 10.1677/joe.0.1620101. J Endocrinol. 1999. PMID: 10396026
Influence of vitamin D3 deficiency and 1,25 dihydroxyvitamin D3 on de novo insulin biosynthesis in the islets of the rat endocrine pancreas.
Bourlon PM, Billaudel B, Faure-Dussert A. Bourlon PM, et al. Among authors: billaudel b. J Endocrinol. 1999 Jan;160(1):87-95. doi: 10.1677/joe.0.1600087. J Endocrinol. 1999. PMID: 9854180
Modulatory role of 1,25 dihydroxyvitamin D3 on pancreatic islet insulin release via the cyclic AMP pathway in the rat.
Bourlon PM, Faure-Dussert A, Billaudel B. Bourlon PM, et al. Among authors: billaudel b. Br J Pharmacol. 1997 Jun;121(4):751-8. doi: 10.1038/sj.bjp.0701204. Br J Pharmacol. 1997. PMID: 9208144 Free PMC article.
Low extracellular calcium enhances beta cell sensitivity to the stimulatory influence of 1,25-dihydroxyvitamin D3 on insulin release by islets from vitamin D3-deficient rats.
Faure-Dussert AG, Delbancut AP, Billaudel BJ. Faure-Dussert AG, et al. Among authors: billaudel bj. Steroids. 1997 Jul;62(7):554-62. doi: 10.1016/s0039-128x(97)00041-x. Steroids. 1997. PMID: 9253796
Regulatory effect of 1,25-dihydroxyvitamin D3 on insulin release and calcium handling via the phospholipid pathway in islets from vitamin D-deficient rats.
Billaudel BJ, Bourlon PM, Sutter BC, Faure-Dussert AG. Billaudel BJ, et al. J Endocrinol Invest. 1995 Oct;18(9):673-82. doi: 10.1007/BF03349788. J Endocrinol Invest. 1995. PMID: 8719297
Thus, 1,25(OH)2D3 may provide supplementary calcium to the B cell by regulating the intracellular signalling processes involving phospholipid metabolism, PKC induction, Ca2+ mobilization and Ca2+ entry by Ca2+ channels....
Thus, 1,25(OH)2D3 may provide supplementary calcium to the B cell by regulating the intracellular signalling processes involving phos …
Effect of 1,25 dihydroxyvitamin D3 on isolated islets from vitamin D3-deprived rats.
Billaudel BJ, Faure AG, Sutter BC. Billaudel BJ, et al. Am J Physiol. 1990 Apr;258(4 Pt 1):E643-8. doi: 10.1152/ajpendo.1990.258.4.E643. Am J Physiol. 1990. PMID: 2185647
A direct influence of 1,25(OH)2D3 on the B-cell was studied in vitro with islets from 5-wk vitamin D3-deprived rats. This hormone (10(-12) to 10(-6) mol/l) added to the incubation medium had a stimulatory dose-dependent effect on insulin response to 8.3 mmol/l glucose 6 h …
A direct influence of 1,25(OH)2D3 on the B-cell was studied in vitro with islets from 5-wk vitamin D3-deprived rats. This hormone (10 …
Stimulatory effect of 1,25-dihydroxyvitamin D3 on calcium handling and insulin secretion by islets from vitamin D3-deficient rats.
Billaudel BJ, Delbancut AP, Sutter BC, Faure AG. Billaudel BJ, et al. Steroids. 1993 Jul;58(7):335-41. doi: 10.1016/0039-128x(93)90094-4. Steroids. 1993. PMID: 8212082
Both of these 1,25-(OH)2D3 influences tended to provide more calcium to the B cell of vitamin D3-deficient rats. But this prerequisite was not sufficient in itself to potentiate the insulin response; indeed, experiments with barium-theophylline suggested that 1,25-(OH)2D3 …
Both of these 1,25-(OH)2D3 influences tended to provide more calcium to the B cell of vitamin D3-deficient rats. But this prerequisit …
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