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A proteolytic fragment of insulin-like growth factor (IGF) binding protein-3 that fails to bind IGFs inhibits the mitogenic effects of IGF-I and insulin.
Lalou C, Lassarre C, Binoux M. Lalou C, et al. Among authors: binoux m. Endocrinology. 1996 Aug;137(8):3206-12. doi: 10.1210/endo.137.8.8754741. Endocrinology. 1996. PMID: 8754741
Insulin-like growth factor binding protein (IGFBP-1) involvement in intrauterine growth retardation: study on IGFBP-1 overexpressing transgenic mice.
Ben Lagha N, Seurin D, Le Bouc Y, Binoux M, Berdal A, Menuelle P, Babajko S. Ben Lagha N, et al. Among authors: binoux m. Endocrinology. 2006 Oct;147(10):4730-7. doi: 10.1210/en.2006-0171. Epub 2006 Jun 29. Endocrinology. 2006. PMID: 16809446
Insulin-like growth factor binding protein-3 stimulates phosphatidylinositol 3-kinase in MCF-7 breast carcinoma cells.
Ricort JM, Binoux M. Ricort JM, et al. Among authors: binoux m. Biochem Biophys Res Commun. 2004 Feb 20;314(4):1044-9. doi: 10.1016/j.bbrc.2004.01.001. Biochem Biophys Res Commun. 2004. PMID: 14751238
Reproductive abnormalities in human insulin-like growth factor-binding protein-1 transgenic male mice.
Froment P, Staub C, Hembert S, Pisselet C, Magistrini M, Delaleu B, Seurin D, Levine JE, Johnson L, Binoux M, Monget P. Froment P, et al. Among authors: binoux m. Endocrinology. 2004 Apr;145(4):2080-91. doi: 10.1210/en.2003-0956. Epub 2004 Jan 15. Endocrinology. 2004. PMID: 14726451
Insulin-like growth factor binding protein-3 increases intracellular calcium concentrations in MCF-7 breast carcinoma cells.
Ricort JM, Lombet A, Lassarre C, Binoux M. Ricort JM, et al. Among authors: binoux m. FEBS Lett. 2002 Sep 11;527(1-3):293-7. doi: 10.1016/s0014-5793(02)03250-7. FEBS Lett. 2002. PMID: 12220677 Free article.
Functional alteration of the somatotrophic axis in transgenic mice with liver-specific expression of human insulin-like growth factor binding protein-1.
Seurin D, Froment P, Bluet-Pajot MT, Epelbaum J, Monget P, Binoux M. Seurin D, et al. Among authors: binoux m. Pediatr Res. 2002 Aug;52(2):168-74. doi: 10.1203/00006450-200208000-00007. Pediatr Res. 2002. PMID: 12149492 Free article.
The amino-terminal region of insulin-like growth factor binding protein-3, (1-95)IGFBP-3, induces apoptosis of MCF-7 breast carcinoma cells.
Bernard L, Babajko S, Binoux M, Ricort JM. Bernard L, et al. Among authors: binoux m. Biochem Biophys Res Commun. 2002 Apr 26;293(1):55-60. doi: 10.1016/S0006-291X(02)00181-X. Biochem Biophys Res Commun. 2002. PMID: 12054563
Insulin-like growth factor-binding protein-3 activates a phosphotyrosine phosphatase. Effects on the insulin-like growth factor signaling pathway.
Ricort JM, Binoux M. Ricort JM, et al. Among authors: binoux m. J Biol Chem. 2002 May 31;277(22):19448-54. doi: 10.1074/jbc.M200439200. Epub 2002 Apr 8. J Biol Chem. 2002. PMID: 11940579 Free article.
Reproductive abnormalities in human IGF binding protein-1 transgenic female mice.
Froment P, Seurin D, Hembert S, Levine JE, Pisselet C, Monniaux D, Binoux M, Monget P. Froment P, et al. Among authors: binoux m. Endocrinology. 2002 May;143(5):1801-8. doi: 10.1210/endo.143.5.8815. Endocrinology. 2002. PMID: 11956162
A targeted partial invalidation of the insulin-like growth factor I receptor gene in mice causes a postnatal growth deficit.
Holzenberger M, Leneuve P, Hamard G, Ducos B, Perin L, Binoux M, Le Bouc Y. Holzenberger M, et al. Among authors: binoux m. Endocrinology. 2000 Jul;141(7):2557-66. doi: 10.1210/endo.141.7.7550. Endocrinology. 2000. PMID: 10875258
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