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Biochemical effects induced by the hexachlorocyclohexanes.
Olivero-Verbel J, Guerrero-Castilla A, Ramos NR. Olivero-Verbel J, et al. Rev Environ Contam Toxicol. 2011;212:1-28. doi: 10.1007/978-1-4419-8453-1_1. Rev Environ Contam Toxicol. 2011. PMID: 21432053 Review.
The hexachlorocyclohexanes (HCHs) are synthetic compounds that have been widely used for the control of pests. ...Humans are exposed to individual HCH isomers through various routes, including ingestion of contaminated water or food, absorbed through the skin or by inhalat …
The hexachlorocyclohexanes (HCHs) are synthetic compounds that have been widely used for the control of pests. ...Humans are exposed …
Long-lasting effects of lindane on mouse spermatogenesis induced by in utero exposure.
Traina ME, Rescia M, Urbani E, Mantovani A, Macrì C, Ricciardi C, Stazi AV, Fazzi P, Cordelli E, Eleuteri P, Leter G, Spanò M. Traina ME, et al. Reprod Toxicol. 2003 Jan-Feb;17(1):25-35. doi: 10.1016/s0890-6238(02)00101-6. Reprod Toxicol. 2003. PMID: 12507655
Long-lasting effects on mouse spermatogenesis induced by prenatal exposure to the insecticide lindane have been investigated by conventional reproductive endpoints complemented by the flow cytometric (FCM) DNA content analysis of testis cells and by the Sperm Chroma …
Long-lasting effects on mouse spermatogenesis induced by prenatal exposure to the insecticide lindane have been investigated b …
CNS biochemical and pharmacological effects of the isomers of hexachlorocyclohexane (lindane) in the mouse.
Fishman BE, Gianutsos G. Fishman BE, et al. Toxicol Appl Pharmacol. 1988 Mar 30;93(1):146-53. doi: 10.1016/0041-008x(88)90034-8. Toxicol Appl Pharmacol. 1988. PMID: 2451320
gamma-Hexachlorocyclohexane (gamma-HCH), the active ingredient of the insecticide lindane, has been shown to be a seizure-inducing agent in mammals. gamma-HCH and two non-convulsant isomers of HCH (alpha and delta) were compared as to their CNS-related pharmacologic …
gamma-Hexachlorocyclohexane (gamma-HCH), the active ingredient of the insecticide lindane, has been shown to be a seizure-inducing
Lindane-induced biochemical perturbations in rat serum and attenuation by omega-3 and Nigella sativa seed oil.
Attia AM, El-Banna SG, Nomeir FR, Abd El-Basser MI. Attia AM, et al. Indian J Biochem Biophys. 2011 Jun;48(3):184-90. Indian J Biochem Biophys. 2011. PMID: 21793310
Lindane (gamma-hexachlorocyclohexane, gamma-HCH), a highly persistent organochlorine insecticide is neurotoxic at acute doses and has been reported to induce oxidative stress in cells and tissues. ...Thus, the results show that omega3 and N.O might prevent oxidative …
Lindane (gamma-hexachlorocyclohexane, gamma-HCH), a highly persistent organochlorine insecticide is neurotoxic at acute doses and has …
Toxicity of lindane induced by oxidative stress and intestinal damage in Caenorhabditis elegans.
Yu Y, Hua X, Chen H, Wang Y, Li Z, Han Y, Xiang M. Yu Y, et al. Environ Pollut. 2020 Sep;264:114731. doi: 10.1016/j.envpol.2020.114731. Epub 2020 May 6. Environ Pollut. 2020. PMID: 32416425
Lindane, a lipophilic pollutant, may be toxic to organisms. To explore the toxic effects of lindane and the underlying mechanisms of this toxicity, the animal model Caenorhabditis elegans (C. elegans) was exposed to lindane for 3 d at environmentally relevant concentration …
Lindane, a lipophilic pollutant, may be toxic to organisms. To explore the toxic effects of lindane and the underlying mechanisms of …
beta-Hexachlorocyclohexane: A Small Molecule with a Big Impact on Human Cellular Biochemistry.
Rubini E, Paglia G, Cannella D, Macone A, Di Sotto A, Gullì M, Altieri F, Eufemi M. Rubini E, et al. Biomedicines. 2020 Nov 16;8(11):505. doi: 10.3390/biomedicines8110505. Biomedicines. 2020. PMID: 33207735 Free PMC article.
Organochlorine pesticides (OCPs) belong to a heterogeneous class of organic compounds blacklisted by the Stockholm Convention in 2009 due to their harmful impact on human health. Among OCPs, beta-hexachlorocyclohexane (beta-HCH) is one of the most widespread and, at the sa …
Organochlorine pesticides (OCPs) belong to a heterogeneous class of organic compounds blacklisted by the Stockholm Convention in 2009 due to …
Mechanistic insights of hepatoprotective effects of curcumin: Therapeutic updates and future prospects.
Khan H, Ullah H, Nabavi SM. Khan H, et al. Food Chem Toxicol. 2019 Feb;124:182-191. doi: 10.1016/j.fct.2018.12.002. Epub 2018 Dec 5. Food Chem Toxicol. 2019. PMID: 30529260 Review.
Curcumin, the active ingredient of turmeric and exhibits therapeutic potential for the treatment of diabetes, cardiovascular disorders and various types of cancers. Curcumin is strong anti-oxidant and anti-inflammatory effects and thus it possesses hepatoprotective propert …
Curcumin, the active ingredient of turmeric and exhibits therapeutic potential for the treatment of diabetes, cardiovascular disorders and v …
The greening of pesticide-environment interactions: some personal observations.
Casida JE. Casida JE. Environ Health Perspect. 2012 Apr;120(4):487-93. doi: 10.1289/ehp.1104405. Epub 2012 Jan 18. Environ Health Perspect. 2012. PMID: 22472325 Free PMC article.
Here I consider some aspects of the discovery, development, and use of ecofriendly or green pesticides (i.e., pesticides that are safe, effective, and biodegradable with minimal adverse secondary effects on the environment). ...Topics considered here include the nee …
Here I consider some aspects of the discovery, development, and use of ecofriendly or green pesticides (i.e., pesticides that are safe, e
Protective effect of the natural product, chaetoglobosin K, on lindane- and dieldrin-induced changes in astroglia: identification of activated signaling pathways.
Sidorova TS, Matesic DF. Sidorova TS, et al. Pharm Res. 2008 Jun;25(6):1297-308. doi: 10.1007/s11095-007-9487-x. Pharm Res. 2008. PMID: 18040759
PURPOSE: The purpose of the present study was to identify the biochemical mechanism(s) of the preventative and reversal effects of Chaetoglobosin K (ChK), a bioactive natural product, on inhibition of gap junction-mediated communication and connexin phosphorylation …
PURPOSE: The purpose of the present study was to identify the biochemical mechanism(s) of the preventative and reversal effects
Influence of hyperthyroidism on lindane-induced hepatotoxicity in the rat.
Videla LA, Smok G, Troncoso P, Simon KA, Junqueira VB, Fernández V. Videla LA, et al. Biochem Pharmacol. 1995 Nov 9;50(10):1557-65. doi: 10.1016/0006-2952(95)02025-x. Biochem Pharmacol. 1995. PMID: 7503757
These parameters were increased further by joint T3 and lindane administration in a magnitude exceeding the sum of the effects produced by the separate treatments. In addition, hyperthyroidism led to Kupffer cell hyperplasia and significant increases in serum glutamate oxa …
These parameters were increased further by joint T3 and lindane administration in a magnitude exceeding the sum of the effects produc …
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