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Clinical implications and utility of field cancerization.
Dakubo GD, Jakupciak JP, Birch-Machin MA, Parr RL. Dakubo GD, et al. Cancer Cell Int. 2007 Mar 15;7:2. doi: 10.1186/1475-2867-7-2. Cancer Cell Int. 2007. PMID: 17362521 Free PMC article.
The mitochondrial genome: a biosensor for early cancer detection?
Parr RL, Jakupciak JP, Birch-Machin MA, Dakubo GD. Parr RL, et al. Expert Opin Med Diagn. 2007 Oct;1(2):169-82. doi: 10.1517/17530059.1.2.169. Expert Opin Med Diagn. 2007. PMID: 23489304
Mitochondrial DNA as a potential tool for early cancer detection.
Parr RL, Dakubo GD, Thayer RE, McKenney K, Birch-Machin MA. Parr RL, et al. Hum Genomics. 2006 Jan;2(4):252-7. doi: 10.1186/1479-7364-2-4-252. Hum Genomics. 2006. PMID: 16460650 Free PMC article.
Somatic mitochondrial DNA mutations in prostate cancer and normal appearing adjacent glands in comparison to age-matched prostate samples without malignant histology.
Parr RL, Dakubo GD, Crandall KA, Maki J, Reguly B, Aguirre A, Wittock R, Robinson K, Alexander JS, Birch-Machin MA, Abdel-Malak M, Froberg MK, Diamandis EP, Thayer RE. Parr RL, et al. J Mol Diagn. 2006 Jul;8(3):312-9. doi: 10.2353/jmoldx.2006.050112. J Mol Diagn. 2006. PMID: 16825503 Free PMC article.
Real-time PCR analysis of a 3895 bp mitochondrial DNA deletion in nonmelanoma skin cancer and its use as a quantitative marker for sunlight exposure in human skin.
Harbottle A, Birch-Machin MA. Harbottle A, et al. Br J Cancer. 2006 Jun 19;94(12):1887-93. doi: 10.1038/sj.bjc.6603178. Epub 2006 May 23. Br J Cancer. 2006. PMID: 16721366 Free PMC article.
Mitochondrial DNA damage in non-melanoma skin cancer.
Durham SE, Krishnan KJ, Betts J, Birch-Machin MA. Durham SE, et al. Br J Cancer. 2003 Jan 13;88(1):90-5. doi: 10.1038/sj.bjc.6600773. Br J Cancer. 2003. PMID: 12556965 Free PMC article.
Using mitochondrial DNA as a biosensor of early cancer development.
Birch-Machin MA. Birch-Machin MA. Br J Cancer. 2005 Aug 8;93(3):271-2. doi: 10.1038/sj.bjc.6602711. Br J Cancer. 2005. PMID: 16079782 Free PMC article. Review. No abstract available.
Real-time polymerase chain reaction analysis of a 3895-bp mitochondrial DNA deletion in epithelial swabs and its use as a quantitative marker for sunlight exposure in human skin.
Harbottle A, Maki J, Reguly B, Wittock R, Robinson K, Parr R, Birch-Machin MA. Harbottle A, et al. Br J Dermatol. 2010 Dec;163(6):1291-5. doi: 10.1111/j.1365-2133.2010.10001.x. Epub 2010 Nov 8. Br J Dermatol. 2010. PMID: 20731654
A maternal line study investigating the 4977-bp mitochondrial DNA deletion.
Thayer RE, Wittock R, Parr R, Zullo S, Birch-Machin MA. Thayer RE, et al. Exp Gerontol. 2003 May;38(5):567-71. doi: 10.1016/s0531-5565(03)00033-0. Exp Gerontol. 2003. PMID: 12742534
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