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CpG islands.
Antequera F, Bird A. Antequera F, et al. EXS. 1993;64:169-85. doi: 10.1007/978-3-0348-9118-9_8. EXS. 1993. PMID: 8418949 Review. No abstract available.
Transcriptional repression by methylation of CpG.
Meehan R, Lewis J, Cross S, Nan X, Jeppesen P, Bird A. Meehan R, et al. J Cell Sci Suppl. 1992;16:9-14. doi: 10.1242/jcs.1992.supplement_16.2. J Cell Sci Suppl. 1992. PMID: 1297654 Review.
Repression of genes by DNA methylation depends on CpG density and promoter strength: evidence for involvement of a methyl-CpG binding protein.
Boyes J, Bird A. Boyes J, et al. EMBO J. 1992 Jan;11(1):327-33. EMBO J. 1992. PMID: 1310933 Free PMC article.
Repression of transcription from densely methylated genes can be mediated by the methyl-CpG binding protein MeCP-1 (Boyes and Bird, 1991). ...This complex can be disrupted by a strong promoter, thereby allowing the methylated gene to be transcribed....
Repression of transcription from densely methylated genes can be mediated by the methyl-CpG binding protein MeCP-1 (Boyes and Bird, 1 …
Use of restriction endonucleases to detect and isolate genes from mammalian cells.
Bickmore WA, Bird AP. Bickmore WA, et al. Methods Enzymol. 1992;216:224-44. doi: 10.1016/0076-6879(92)16024-e. Methods Enzymol. 1992. PMID: 1336093 No abstract available.
The essentials of DNA methylation.
Bird A. Bird A. Cell. 1992 Jul 10;70(1):5-8. doi: 10.1016/0092-8674(92)90526-i. Cell. 1992. PMID: 1377983 Review. No abstract available.
Characterization of MeCP2, a vertebrate DNA binding protein with affinity for methylated DNA.
Meehan RR, Lewis JD, Bird AP. Meehan RR, et al. Nucleic Acids Res. 1992 Oct 11;20(19):5085-92. doi: 10.1093/nar/20.19.5085. Nucleic Acids Res. 1992. PMID: 1408825 Free PMC article.
DNAs containing thymidine which has a methyl group at position 5 are not ligands for the MeCPs. The possible role of MeCP2 in methylation-associated gene inactivation was tested in in vitro transcription extracts. ...
DNAs containing thymidine which has a methyl group at position 5 are not ligands for the MeCPs. The possible role of MeCP2 in methyla …
Purification, sequence, and cellular localization of a novel chromosomal protein that binds to methylated DNA.
Lewis JD, Meehan RR, Henzel WJ, Maurer-Fogy I, Jeppesen P, Klein F, Bird A. Lewis JD, et al. Cell. 1992 Jun 12;69(6):905-14. doi: 10.1016/0092-8674(92)90610-o. Cell. 1992. PMID: 1606614
Here we report the identification, purification, and cDNA cloning of a novel MeCP called MeCP2. Unlike MeCP1, the new protein is able to bind to DNA that contains a single methyl-CpG pair. ...In mouse, for example, MeCP2 is concentrated in pericentromeric heterochro …
Here we report the identification, purification, and cDNA cloning of a novel MeCP called MeCP2. Unlike MeCP1, the new protein is able …
DNA methylation and chromatin structure.
Lewis J, Bird A. Lewis J, et al. FEBS Lett. 1991 Jul 22;285(2):155-9. doi: 10.1016/0014-5793(91)80795-5. FEBS Lett. 1991. PMID: 1855583 Review.
A protein (MeCP) which binds specifically to methylated DNA has been identified. The properties of MeCP could account for the effects of DNA methylation on both chromatin and transcription....
A protein (MeCP) which binds specifically to methylated DNA has been identified. The properties of MeCP could account for the effects
DNA methylation inhibits transcription indirectly via a methyl-CpG binding protein.
Boyes J, Bird A. Boyes J, et al. Cell. 1991 Mar 22;64(6):1123-34. doi: 10.1016/0092-8674(91)90267-3. Cell. 1991. PMID: 2004419
The mediator of repression had properties indistinguishable from those of a methyl-CpG binding protein (MeCP-1) that has been previously identified. ...
The mediator of repression had properties indistinguishable from those of a methyl-CpG binding protein (MeCP-1) that has been previou …
1,319 results
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