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Granzyme A Deficiency Breaks Immune Tolerance and Promotes Autoimmune Diabetes Through a Type I Interferon-Dependent Pathway.
Mollah ZUA, Quah HS, Graham KL, Jhala G, Krishnamurthy B, Dharma JFM, Chee J, Trivedi PM, Pappas EG, Mackin L, Chu EPF, Akazawa S, Fynch S, Hodson C, Deans AJ, Trapani JA, Chong MMW, Bird PI, Brodnicki TC, Thomas HE, Kay TWH. Mollah ZUA, et al. Among authors: bird pi. Diabetes. 2017 Dec;66(12):3041-3050. doi: 10.2337/db17-0517. Epub 2017 Jul 21. Diabetes. 2017. PMID: 28733313
Cathepsin H is an additional convertase of pro-granzyme B.
D'Angelo ME, Bird PI, Peters C, Reinheckel T, Trapani JA, Sutton VR. D'Angelo ME, et al. Among authors: bird pi. J Biol Chem. 2010 Jul 2;285(27):20514-9. doi: 10.1074/jbc.M109.094573. Epub 2010 Apr 30. J Biol Chem. 2010. PMID: 20435891 Free PMC article.
A role for granzyme M in TLR4-driven inflammation and endotoxicosis.
Anthony DA, Andrews DM, Chow M, Watt SV, House C, Akira S, Bird PI, Trapani JA, Smyth MJ. Anthony DA, et al. Among authors: bird pi. J Immunol. 2010 Aug 1;185(3):1794-803. doi: 10.4049/jimmunol.1000430. Epub 2010 Jun 28. J Immunol. 2010. PMID: 20585036
A central role for Bid in granzyme B-induced apoptosis.
Waterhouse NJ, Sedelies KA, Browne KA, Wowk ME, Newbold A, Sutton VR, Clarke CJ, Oliaro J, Lindemann RK, Bird PI, Johnstone RW, Trapani JA. Waterhouse NJ, et al. Among authors: bird pi. J Biol Chem. 2005 Feb 11;280(6):4476-82. doi: 10.1074/jbc.M410985200. Epub 2004 Dec 1. J Biol Chem. 2005. PMID: 15574417 Free article.
202 results