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A monoclonal antibody to O-acetyl-GD2 ganglioside and not to GD2 shows potent anti-tumor activity without peripheral nervous system cross-reactivity.
Alvarez-Rueda N, Desselle A, Cochonneau D, Chaumette T, Clemenceau B, Leprieur S, Bougras G, Supiot S, Mussini JM, Barbet J, Saba J, Paris F, Aubry J, Birklé S. Alvarez-Rueda N, et al. Among authors: birkle s. PLoS One. 2011;6(9):e25220. doi: 10.1371/journal.pone.0025220. Epub 2011 Sep 22. PLoS One. 2011. PMID: 21966461 Free PMC article.
Anti-Gb3 monoclonal antibody inhibits angiogenesis and tumor development.
Desselle A, Chaumette T, Gaugler MH, Cochonneau D, Fleurence J, Dubois N, Hulin P, Aubry J, Birklé S, Paris F. Desselle A, et al. Among authors: birkle s. PLoS One. 2012;7(11):e45423. doi: 10.1371/journal.pone.0045423. Epub 2012 Nov 26. PLoS One. 2012. PMID: 23189121 Free PMC article.
Chimeric antibody c.8B6 to O-acetyl-GD2 mediates the same efficient anti-neuroblastoma effects as therapeutic ch14.18 antibody to GD2 without antibody induced allodynia.
Terme M, Dorvillius M, Cochonneau D, Chaumette T, Xiao W, Diccianni MB, Barbet J, Yu AL, Paris F, Sorkin LS, Birklé S. Terme M, et al. Among authors: birkle s. PLoS One. 2014 Feb 10;9(2):e87210. doi: 10.1371/journal.pone.0087210. eCollection 2014. PLoS One. 2014. PMID: 24520328 Free PMC article.
Targeting O-Acetyl-GD2 Ganglioside for Cancer Immunotherapy.
Fleurence J, Fougeray S, Bahri M, Cochonneau D, Clémenceau B, Paris F, Heczey A, Birklé S. Fleurence J, et al. Among authors: birkle s. J Immunol Res. 2017;2017:5604891. doi: 10.1155/2017/5604891. Epub 2017 Jan 5. J Immunol Res. 2017. PMID: 28154831 Free PMC article. Review.
Impairing temozolomide resistance driven by glioma stem-like cells with adjuvant immunotherapy targeting O-acetyl GD2 ganglioside.
Fleurence J, Bahri M, Fougeray S, Faraj S, Vermeulen S, Pinault E, Geraldo F, Oliver L, Véziers J, Marquet P, Rabé M, Gratas C, Vallette F, Pecqueur C, Paris F, Birklé S. Fleurence J, et al. Among authors: birkle s. Int J Cancer. 2020 Jan 15;146(2):424-438. doi: 10.1002/ijc.32533. Epub 2019 Jul 13. Int J Cancer. 2020. PMID: 31241171 Free article.
33 results