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The stimulatory G protein of adenylyl cyclase, Gs, also stimulates dihydropyridine-sensitive Ca2+ channels. Evidence for direct regulation independent of phosphorylation by cAMP-dependent protein kinase or stimulation by a dihydropyridine agonist.
Yatani A, Imoto Y, Codina J, Hamilton SL, Brown AM, Birnbaumer L. Yatani A, et al. Among authors: birnbaumer l. J Biol Chem. 1988 Jul 15;263(20):9887-95. J Biol Chem. 1988. PMID: 2454923
We demonstrated recently that purified preparations of Gs, the stimulatory G protein of adenylyl cyclase, can stabilize Ca2+ channels in inside-out cardiac ventricle membrane patches stimulated prior to excision by the beta-adrenergic agonist isoprenaline or by the dihydropyridin …
We demonstrated recently that purified preparations of Gs, the stimulatory G protein of adenylyl cyclase, can stabilize Ca2+ channels in ins …
Hormone-stimulated desensitization of hormone-dependent adenylyl cyclase. Dual action of luteninizing hormone on pig graafian follicle membranes.
Bockaert J, Hunzicker-Dunn M, Birnbaumer L. Bockaert J, et al. Among authors: birnbaumer l. J Biol Chem. 1976 May 10;251(9):2653-63. J Biol Chem. 1976. PMID: 816796
LH-stimulated desensitization was detected also in washed membrane particles derived from dissected rabbit Graafian follicles, whose adenylyl cyclase becomes desensitized in vivo within minutes after human chorionic gonadotropin injection (Hunzicker-Dunn, M., and Birnbaumer
LH-stimulated desensitization was detected also in washed membrane particles derived from dissected rabbit Graafian follicles, whose adenyly …
Guanosine 5'-O-(3-thiotriphosphate) reduces ADP-ribosylation of the inhibitory guanine nucleotide-binding regulatory protein of adenylyl cyclase (Ni) by pertussis toxin without causing dissociation of the subunits of Ni. Evidence of existence of heterotrimeric pt+ and pt- conformations of Ni.
Mattera R, Codina J, Sekura RD, Birnbaumer L. Mattera R, et al. Among authors: birnbaumer l. J Biol Chem. 1987 Aug 15;262(23):11247-51. J Biol Chem. 1987. PMID: 3112155
Two effects were discerned: a stimulation of the ADP-ribosyltransferase activity of the toxin, akin to what was described for ATP and GDP in a previous report (Mattera, R., Codina, J., Sekura, R., and Birnbaumer, L. (1986) J. Biol. Chem. 261, 11173-11179), and a dec …
Two effects were discerned: a stimulation of the ADP-ribosyltransferase activity of the toxin, akin to what was described for ATP and GDP in …
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