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Therapeutic potential of a synthetic lethal interaction between the MYC proto-oncogene and inhibition of aurora-B kinase.
Yang D, Liu H, Goga A, Kim S, Yuneva M, Bishop JM. Yang D, et al. Proc Natl Acad Sci U S A. 2010 Aug 3;107(31):13836-41. doi: 10.1073/pnas.1008366107. Epub 2010 Jul 19. Proc Natl Acad Sci U S A. 2010. PMID: 20643922 Free PMC article.
The protooncogene MYC can break B cell tolerance.
Refaeli Y, Field KA, Turner BC, Trumpp A, Bishop JM. Refaeli Y, et al. Proc Natl Acad Sci U S A. 2005 Mar 15;102(11):4097-102. doi: 10.1073/pnas.0409832102. Epub 2005 Mar 7. Proc Natl Acad Sci U S A. 2005. PMID: 15753301 Free PMC article.
A screen for genes that suppress loss of contact inhibition: identification of ING4 as a candidate tumor suppressor gene in human cancer.
Kim S, Chin K, Gray JW, Bishop JM. Kim S, et al. Proc Natl Acad Sci U S A. 2004 Nov 16;101(46):16251-6. doi: 10.1073/pnas.0407158101. Epub 2004 Nov 4. Proc Natl Acad Sci U S A. 2004. PMID: 15528276 Free PMC article.
Negative control of the Myc protein by the stress-responsive kinase Pak2.
Huang Z, Traugh JA, Bishop JM. Huang Z, et al. Mol Cell Biol. 2004 Feb;24(4):1582-94. doi: 10.1128/mcb.24.4.1582-1594.2004. Mol Cell Biol. 2004. PMID: 14749374 Free PMC article.
Inhibition of CDK1 as a potential therapy for tumors over-expressing MYC.
Goga A, Yang D, Tward AD, Morgan DO, Bishop JM. Goga A, et al. Nat Med. 2007 Jul;13(7):820-7. doi: 10.1038/nm1606. Epub 2007 Jun 24. Nat Med. 2007. PMID: 17589519
MET and MYC cooperate in mammary tumorigenesis.
Welm AL, Kim S, Welm BE, Bishop JM. Welm AL, et al. Proc Natl Acad Sci U S A. 2005 Mar 22;102(12):4324-9. doi: 10.1073/pnas.0500470102. Epub 2005 Feb 28. Proc Natl Acad Sci U S A. 2005. PMID: 15738393 Free PMC article.
MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancer.
Shachaf CM, Kopelman AM, Arvanitis C, Karlsson A, Beer S, Mandl S, Bachmann MH, Borowsky AD, Ruebner B, Cardiff RD, Yang Q, Bishop JM, Contag CH, Felsher DW. Shachaf CM, et al. Nature. 2004 Oct 28;431(7012):1112-7. doi: 10.1038/nature03043. Epub 2004 Oct 10. Nature. 2004. PMID: 15475948
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