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Arsenic induces apoptosis in mouse liver is mitochondria dependent and is abrogated by N-acetylcysteine.
Santra A, Chowdhury A, Ghatak S, Biswas A, Dhali GK. Santra A, et al. Toxicol Appl Pharmacol. 2007 Apr 15;220(2):146-55. doi: 10.1016/j.taap.2006.12.029. Epub 2007 Jan 9. Toxicol Appl Pharmacol. 2007. PMID: 17303202
Arsenicosis, caused by arsenic contamination of drinking water supplies, is a major public health problem in India and Bangladesh. ...Pretreatment of NAC to arsenic-treated mice abrogated all these alteration suggesting a glutathione (GSH)-dependent mechanism. ...
Arsenicosis, caused by arsenic contamination of drinking water supplies, is a major public health problem in India and Bangladesh. .. …
Oxidative stress and hepatic stellate cell activation are key events in arsenic induced liver fibrosis in mice.
Ghatak S, Biswas A, Dhali GK, Chowdhury A, Boyer JL, Santra A. Ghatak S, et al. Toxicol Appl Pharmacol. 2011 Feb 15;251(1):59-69. doi: 10.1016/j.taap.2010.11.016. Epub 2010 Dec 4. Toxicol Appl Pharmacol. 2011. PMID: 21134390 Free PMC article.
We evaluated hepatic fibrogenesis after long term arsenic exposure in a murine model. BALB/c mice were exposed to arsenic by daily gavages of 6 μg/gm body weight for 1 year and were evaluated for markers of hepatic oxidative stress and fibrosis, as well as pro-inflammatory …
We evaluated hepatic fibrogenesis after long term arsenic exposure in a murine model. BALB/c mice were exposed to arsenic by daily ga …
Isoniazid and Rifampicin Produce Hepatic Fibrosis through an Oxidative Stress-Dependent Mechanism.
Biswas A, Santra S, Bishnu D, Dhali GK, Chowdhury A, Santra A. Biswas A, et al. Int J Hepatol. 2020 Apr 23;2020:6987295. doi: 10.1155/2020/6987295. eCollection 2020. Int J Hepatol. 2020. PMID: 32373368 Free PMC article.
METHODS: A combined dose of INH (50 mg) and RMP (100 mg) per kg body weight per day was administered to mice by oral gavage, 6 days a week, for 4 to 24 weeks for the assessment of liver injury, oxidative stress, and development of hepatic fibrosis, including demonst …
METHODS: A combined dose of INH (50 mg) and RMP (100 mg) per kg body weight per day was administered to mice by oral gavage, 6 days …
Redundancy in information transmission in a two-step cascade.
Biswas A, Banik SK. Biswas A, et al. Phys Rev E. 2016 May;93(5):052422. doi: 10.1103/PhysRevE.93.052422. Epub 2016 May 31. Phys Rev E. 2016. PMID: 27300938
We present a stochastic framework to study signal transmission in a generic two-step cascade S→X→Y. Starting from a set of Langevin equations obeying Gaussian noise processes we calculate the variance and covariance while considering both linear and nonlinear …
We present a stochastic framework to study signal transmission in a generic two-step cascade S→X→Y. Starting from a set …
Multivariate information processing characterizes fitness of a cascaded gene-transcription machinery.
Biswas A. Biswas A. Chaos. 2019 Jun;29(6):063108. doi: 10.1063/1.5092447. Chaos. 2019. PMID: 31266314
We report that a genetic two-step activation cascade processes diverse flavors of information, e.g., synergy, redundancy, and unique information. ...
We report that a genetic two-step activation cascade processes diverse flavors of information, e.g., synergy, redundancy, and unique …
Interplay of synergy and redundancy in diamond motif.
Biswas A, Banik SK. Biswas A, et al. Chaos. 2018 Oct;28(10):103102. doi: 10.1063/1.5044606. Chaos. 2018. PMID: 30384656
In the current study, we use this formalism to obtain a comprehensive understanding of the relative information processing mechanism in a diamond motif and two of its sub-motifs, namely, bifurcation and integration motif embedded within the diamond motif. ...Accordi …
In the current study, we use this formalism to obtain a comprehensive understanding of the relative information processing mechanism …
Impact of trainee-driven Antimicrobial Stewardship Program in a high burden resource-limited setting.
Banerjee S, Gupta N, Ray Y, Kodan P, Khot WY, Fazal F, Nyas VKM, Soneja M, Vikram N, Biswas A, Kapil A, Wig N. Banerjee S, et al. Among authors: biswas a. Infez Med. 2020 Sep 1;28(3):367-372. Infez Med. 2020. PMID: 32920572 Free article.
Enhanced accumulation of reduced glutathione by Scopoletin improves survivability of dopaminergic neurons in Parkinson's model.
Pradhan P, Majhi O, Biswas A, Joshi VK, Sinha D. Pradhan P, et al. Among authors: biswas a. Cell Death Dis. 2020 Sep 10;11(9):739. doi: 10.1038/s41419-020-02942-8. Cell Death Dis. 2020. PMID: 32913179
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