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Failure to detect human cytomegalovirus DNA in peripheral blood leukocytes of healthy blood donors by the polymerase chain reaction.
Bitsch A, Kirchner H, Dupke R, Bein G. Bitsch A, et al. Transfusion. 1992 Sep;32(7):612-7. doi: 10.1046/j.1537-2995.1992.32792391032.x. Transfusion. 1992. PMID: 1325693
The transmission of cytomegalovirus (CMV) by blood transfusion may have a major effect on certain immunocompromised patients. ...A highly sensitive and specific PCR assay was developed for the detection of CMV DNA in peripheral blood leukocytes. With this protocol, …
The transmission of cytomegalovirus (CMV) by blood transfusion may have a major effect on certain immunocompromised patients. ...A
A longitudinal prospective study of cytomegalovirus pp65 antigenemia in renal transplant recipients.
Bein G, Bitsch A, Hoyer J, Steinhoff J, Fricke L, Machnik H, Dennin R, Kirchner H. Bein G, et al. Transpl Int. 1993;6(4):185-90. doi: 10.1007/BF00337097. Transpl Int. 1993. PMID: 8394089
Cytomegalovirus (CMV)-encoded pp65 antigen in peripheral blood leukocytes (CMV antigenemia) was investigated in 1017 serial samples from 64 patients for 16 weeks after renal transplantation in a prospective study. ...The sensitivity in defining a CMV syndrome was 10 …
Cytomegalovirus (CMV)-encoded pp65 antigen in peripheral blood leukocytes (CMV antigenemia) was investigated in 1017 serial samples from 64 …
The long persistence of CMV DNA in the blood of renal transplant patients after recovery from CMV infection.
Bitsch A, Kirchner H, Dennin R, Hoyer J, Fricke L, Steinhoff J, Sack K, Bein G. Bitsch A, et al. Transplantation. 1993 Jul;56(1):108-13. doi: 10.1097/00007890-199307000-00020. Transplantation. 1993. PMID: 8392761
In 41 renal transplant patients the PCR assay yielded a sensitivity of 100% compared with 87.5% of the antigenemia assay. Specificities reached 67% and 92.5%, respectively. ...Even after successful treatment of symptomatic CMV disease, DNA was present for a period o …
In 41 renal transplant patients the PCR assay yielded a sensitivity of 100% compared with 87.5% of the antigenemia assay. Specificiti …
Cytomegalovirus transcripts in peripheral blood leukocytes of actively infected transplant patients detected by reverse transcription-polymerase chain reaction.
Bitsch A, Kirchner H, Dupke R, Bein G. Bitsch A, et al. J Infect Dis. 1993 Mar;167(3):740-3. doi: 10.1093/infdis/167.3.740. J Infect Dis. 1993. PMID: 8382724
In an effort to examine human cytomegalovirus (CMV) infections on the transcript level in vivo, a reverse transcription-polymerase chain reaction (RT-PCR) for the detection of CMV mRNA in human peripheral blood leukocytes (PBL) was developed. ...These findings suggest that …
In an effort to examine human cytomegalovirus (CMV) infections on the transcript level in vivo, a reverse transcription-polymerase ch …
Detection and quantification of latently infected B lymphocytes in Epstein-Barr virus-seropositive, healthy individuals by polymerase chain reaction.
Wagner HJ, Bein G, Bitsch A, Kirchner H. Wagner HJ, et al. J Clin Microbiol. 1992 Nov;30(11):2826-9. doi: 10.1128/JCM.30.11.2826-2829.1992. J Clin Microbiol. 1992. PMID: 1333480 Free PMC article.
We designed a highly sensitive and specific polymerase chain reaction assay for the detection of Epstein-Barr virus (EBV)-related sequences in B-cell DNA of EBV-seropositive healthy individuals. ...When the results of amplifying the diluted plasmid were used as a se …
We designed a highly sensitive and specific polymerase chain reaction assay for the detection of Epstein-Barr virus (EBV)-related seq …
The role of nongenotoxic mechanisms in arylamine carcinogenesis.
Neumann HG, Ambs S, Bitsch A. Neumann HG, et al. Environ Health Perspect. 1994 Oct;102 Suppl 6(Suppl 6):173-6. doi: 10.1289/ehp.94102s6173. Environ Health Perspect. 1994. PMID: 7889843 Free PMC article.
The growth of preneoplastic nodules during the feeding of a carcinogenic 2-acetylaminofluorene (2-AAF) regimen is preceded by several alterations in the physiologic homeostasis. ...
The growth of preneoplastic nodules during the feeding of a carcinogenic 2-acetylaminofluorene (2-AAF) regimen is preceded by several …
Dose response of early effects related to tumor promotion of 2-acetylaminofluorene.
Bitsch A, Hadjiolov N, Klöhn PC, Bergmann O, Zwirner-Baier I, Neumann HG. Bitsch A, et al. Toxicol Sci. 2000 May;55(1):44-51. doi: 10.1093/toxsci/55.1.44. Toxicol Sci. 2000. PMID: 10788558
These mitochondrial effects are thought to trigger apoptosis and regenerative proliferation, which alters the liver lobule in a cirrhosis-like manner. A situation is generated which favors the growth of initiated cells. To test this sequence of events, the dose depe …
These mitochondrial effects are thought to trigger apoptosis and regenerative proliferation, which alters the liver lobule in a cirrh …
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