Bitsch F - Search Results

1

Allosteric non-bisphosphonate FPPS inhibitors identified by fragment-based discovery.

Jahnke W, Rondeau JM, Cotesta S, Marzinzik A, Pellé X, Geiser M, Strauss A, Götte M, Bitsch F, Hemmig R, Henry C, Lehmann S, Glickman JF, Roddy TP, Stout SJ, Green JR. Jahnke W, et al. Among authors: bitsch f. Nat Chem Biol. 2010 Sep;6(9):660-6. doi: 10.1038/nchembio.421. Epub 2010 Aug 15. Nat Chem Biol. 2010. PMID: 20711197

2

Structural basis for the exceptional in vivo efficacy of bisphosphonate drugs.

Rondeau JM, Bitsch F, Bourgier E, Geiser M, Hemmig R, Kroemer M, Lehmann S, Ramage P, Rieffel S, Strauss A, Green JR, Jahnke W. Rondeau JM, et al. Among authors: bitsch f. ChemMedChem. 2006 Feb;1(2):267-73. doi: 10.1002/cmdc.200500059. ChemMedChem. 2006. PMID: 16892359

3

Evidence for ligand-independent transcriptional activation of the human estrogen-related receptor alpha (ERRalpha): crystal structure of ERRalpha ligand binding domain in complex with peroxisome proliferator-activated receptor coactivator-1alpha.

Kallen J, Schlaeppi JM, Bitsch F, Filipuzzi I, Schilb A, Riou V, Graham A, Strauss A, Geiser M, Fournier B. Kallen J, et al. Among authors: bitsch f. J Biol Chem. 2004 Nov 19;279(47):49330-7. doi: 10.1074/jbc.M407999200. Epub 2004 Aug 26. J Biol Chem. 2004. PMID: 15337744 Free article.

4

Efficient uniform isotope labeling of Abl kinase expressed in Baculovirus-infected insect cells.

Strauss A, Bitsch F, Fendrich G, Graff P, Knecht R, Meyhack B, Jahnke W. Strauss A, et al. Among authors: bitsch f. J Biomol NMR. 2005 Apr;31(4):343-9. doi: 10.1007/s10858-005-2451-3. J Biomol NMR. 2005. PMID: 15929001

5

Amino-acid-type selective isotope labeling of proteins expressed in Baculovirus-infected insect cells useful for NMR studies.

Strauss A, Bitsch F, Cutting B, Fendrich G, Graff P, Liebetanz J, Zurini M, Jahnke W. Strauss A, et al. Among authors: bitsch f. J Biomol NMR. 2003 Aug;26(4):367-72. doi: 10.1023/a:1024013111478. J Biomol NMR. 2003. PMID: 12815263

6

X-ray structure of the hRORalpha LBD at 1.63 A: structural and functional data that cholesterol or a cholesterol derivative is the natural ligand of RORalpha.

Kallen JA, Schlaeppi JM, Bitsch F, Geisse S, Geiser M, Delhon I, Fournier B. Kallen JA, et al. Among authors: bitsch f. Structure. 2002 Dec;10(12):1697-707. doi: 10.1016/s0969-2126(02)00912-7. Structure. 2002. PMID: 12467577 Free article.

7

Novel beta-lactam derivatives: potent and selective inhibitors of the chymotrypsin-like activity of the human 20S proteasome.

Imbach P, Lang M, García-Echeverría C, Guagnano V, Noorani M, Roesel J, Bitsch F, Rihs G, Furet P. Imbach P, et al. Among authors: bitsch f. Bioorg Med Chem Lett. 2007 Jan 15;17(2):358-62. doi: 10.1016/j.bmcl.2006.10.047. Epub 2006 Oct 24. Bioorg Med Chem Lett. 2007. PMID: 17095212

8

Crystal structure of the human RORalpha Ligand binding domain in complex with cholesterol sulfate at 2.2 A.

Kallen J, Schlaeppi JM, Bitsch F, Delhon I, Fournier B. Kallen J, et al. Among authors: bitsch f. J Biol Chem. 2004 Apr 2;279(14):14033-8. doi: 10.1074/jbc.M400302200. Epub 2004 Jan 13. J Biol Chem. 2004. PMID: 14722075 Free article.

9

Identification of natural ligands of retinoic acid receptor-related orphan receptor alpha ligand-binding domain expressed in Sf9 cells--a mass spectrometry approach.

Bitsch F, Aichholz R, Kallen J, Geisse S, Fournier B, Schlaeppi JM. Bitsch F, et al. Anal Biochem. 2003 Dec 1;323(1):139-49. doi: 10.1016/j.ab.2003.08.029. Anal Biochem. 2003. PMID: 14622968

10

Optimization of the anti-(human CD3) immunotoxin DT389-scFv(UCHT1) N-terminal sequence to yield a homogeneous protein.

Hexham JM, King V, Dudas D, Graff P, Mahnke M, Wang YK, Goetschy JF, Plattner D, Zurini M, Bitsch F, Lake P, Digan ME. Hexham JM, et al. Among authors: bitsch f. Biotechnol Appl Biochem. 2001 Dec;34(3):183-7. doi: 10.1042/ba20010073. Biotechnol Appl Biochem. 2001. PMID: 11730486

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

43 results

Search Page